Protein name:
Cyclic nucleotide-gated cation channel beta-1 ;
Alternative:
Cyclic nucleotide-gated cation channel 4 (CNG channel 4;CNG-4;CNG4) ;240 kDa protein of rod photoreceptor CNG-channel ;Cyclic nucleotide-gated cation channel modulatory subunit ;Cyclic nucleotide-gated cation channel gamma ;Glutamic acid-rich protein (GARP) ;Cyclic nucleotide-gated channel beta-1 (CNG channel beta-1) ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Heterooligomeric complex with CNGA1.
Function:
Subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MLGWVQRVLP | QPPGTPQKTK | QEEEGTEPEP | ELEPKPETAP | EETELEEVSL |
100:
PPEEPCVGKE | VAAVTLGPQG | TQETALTPPT | SLQAQVSVAP | EAHSSPRGWV |
150:
LTWLRKGVEK | VVPQPAHSSR | PSQNIAAGLE | SPDQQAGAQI | LGQCGTGGSD |
200:
EPSEPSRAED | PGPGPWLLRW | FEQNLEKMLP | QPPKISEGWR | DEPTDAALGP |
250:
EPPGPALEIK | PMLQAQESPS | LPAPGPPEPE | EEPIPEPQPT | IQASSLPPPQ |
300:
DSARLMAWIL | HRLEMALPQP | VIRGKGGEQE | SDAPVTCDVQ | TISILPGEQE |
350:
ESHLILEEVD | PHWEEDEHQE | GSTSTSPRTS | EAAPADEEKG | KVVEQTPREL |
400:
PRIQEEKEDE | EEEKEDGEEE | EEEGREKEEE | EGEEKEEEEG | REKEEEEGEK |
450:
KEEEGREKEE | EEGGEKEDEE | GREKEEEEGR | GKEEEEGGEK | EEEEGRGKEE |
500:
VEGREEEEDE | EEEQDHSVLL | DSYLVPQSEE | DRSEESETQD | QSEVGGAQAQ |
550:
GEVGGAQALS | EESETQDQSE | VGGAQDQSEV | GGAQAQGEVG | GAQEQDGVGG |
600:
AQDQSTSHQE | LQEEALADSS | GVPATEEHPE | LQVEDADADS | RPLIAEENPP |
650:
SPVQLPLSPA | KSDTLAVPGS | ATGSLRKRLP | SQDDEAEELK | MLSPAASPVV |
700:
AWSDPTSPQG | TDDQDRATST | ASQNSAIIND | RLQELVKLFK | ERTEKVKEKL |
750:
IDPDVTSDEE | SPKPSPAKKA | PEPAPEVKPA | EAGQVEEEHY | CEMLCCKFKR |
800:
RPWKKYQFPQ | SIDPLTNLMY | ILWLFFVVLA | WNWNCWLIPV | RWAFPYQTPD |
850:
NIHLWLLMDY | LCDLIYLLDI | TVFQMRLQFV | RGGDIITDKK | EMRNNYVKSQ |
900:
RFKMDMLCLL | PLDLLYLKFG | VNPLLRLPRC | LKYMAFFEFN | NRLESILSKA |
950:
YVYRVIRTTA | YLLYSLHLNS | CLYYWASAYE | GLGSTHWVYD | GVGNSYIRCY |
1000:
YWAVKTLITI | GGLPDPRTLF | EIVFQGLNYF | TGVFAFSVMI | GQMRDVVGAA |
1050:
TAGQTYYRSC | MDSTVKYMNF | YKIPRSVQNR | VKTWYEYTWH | SQGMLDESEL |
1100:
MVQLPDKMRL | DLAIDVNYSI | VSKVALFQGC | DRQMIFDMLK | RLRSVVYLPN |
1150:
DYVCKKGEIG | REMYIIQAGQ | VQVLGGPDGK | SVLVTLKAGS | VFGEISLLAV |
1200:
GGGNRRTANV | VAHGFTNLFI | LDKKDLNEIL | VHYPESQKLL | RKKARRMLRN |
1250:
NNKPKEKSVL | ILPPRAGTPK | LFNAALAAAG | KMGAKGGRGG | RLALLRARLK |
1300:
ELAALEAAAR | QQQLLEQAKS | SEDAAVGEEG | SASPEQPPRP | EPPAPEAPAP |
1350:
EPTAPEPLAP | EAPAPEAPAP | SSPPPASQER | PEGDKDAARP | EEHPVRIHVT |
1394:
LGPDPSEQIL | LVEVPEKQEE | KEKKEEETEE | KEEGEEARKE | KEEE
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
ELISA Kit for Bovine Cyclic nucleotide-gated cation channel beta-1
ELISA Kit for Bovine Cyclic nucleotide-gated cation channel beta-1
CLIA Kit for Bovine Cyclic nucleotide-gated cation channel beta-1
CLIA Kit for Bovine Cyclic nucleotide-gated cation channel beta-1
Polyclonal Antibody for Bovine Cyclic nucleotide-gated cation channel beta-1
Polyclonal Antibody for Bovine Cyclic nucleotide-gated cation channel beta-1
Monoclonal Antibody for Bovine Cyclic nucleotide-gated cation channel beta-1
Monoclonal Antibody for Bovine Cyclic nucleotide-gated cation channel beta-1
Protein for Bovine Cyclic nucleotide-gated cation channel beta-1
Protein for Bovine Cyclic nucleotide-gated cation channel beta-1
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
"A 240 kDa protein represents the complete beta subunit of the cyclic nucleotide-gated channel from rod photoreceptor."
Koerschen H.G.
,
Illing M.
,
Seifert R.
,
Sesti F.
,
Williams A.
,
Gotzes S.
,
Colville C.
,
Mueller F.
,
Dose A.
,
Godde M.
,
Molday L.
,
Kaupp U.B.
,
Molday R.S.
Neuron15:627-636(1995)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM CNG4A);PARTIAL PROTEIN SEQUENCE
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM CNG4C);ALTERNATIVE SPLICING (ISOFORMS CNG4D AND CNG4E)
tissue :
Testis .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM GARP1)
tissue :
Retina .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ALTERNATIVE SPLICING (ISOFORMS GARP1 AND GARP2)
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBUNIT