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Index > Protein center > CNIH1(Gene name) > Human
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  • CNIH1 (Gene name),
  • Protein cornichon homolog 1 (Protein name ),  CNIH1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CNIH1(UNQ155/PRO181;CNIH;CNIL);
    Protein name:
    Protein cornichon homolog 1(CNIH-1);
    Alternative:
    Protein cornichon homolog;Cornichon family AMPA receptor auxiliary protein 1;T-cell growth-associated molecule 77(TGAM77);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with AREG immature precursor and with immature TGFA, i.e. with a prosegment and lacking full N-glycosylation, but not with the fully N-glycosylated form. In the Golgi apparatus, may form a complex with GORASP55 and transmembrane TGFA.
    Function:
    Involved in the selective transport and maturation of TGF-alpha family proteins.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein Golgi apparatus membrane Located primarily in the ER; may cycle between the ER and the Golgi apparatus.
    Protein Attributes:
    Sequence length:
    144
    Sequence:
    50:
    MAFTFAAFCY | MLALLLTAAL | IFFAIWHIIA | FDELKTDYKN | PIDQCNTLNP | 
    100:
    LVLPEYLIHA | FFCVMFLCAA | EWLTLGLNMP | LLAYHIWRYM | SRPVMSGPGL | 
    144:
    YDPTTIMNAD | ILAYCQKEGW | CKLAFYLLAF | FYYLYGMIYV | LVSS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    MIM:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human CNIH-1
    ELISA Kit for Human CNIH-1
    ELISA Kit for Human CNIH-1
    CLIA Kit for Human CNIH-1
    CLIA Kit for Human CNIH-1
    CLIA Kit for Human CNIH-1
    Polyclonal Antibody for Human CNIH-1
    Polyclonal Antibody for Human CNIH-1
    Polyclonal Antibody for Human CNIH-1
    Monoclonal Antibody for Human CNIH-1
    Monoclonal Antibody for Human CNIH-1
    Monoclonal Antibody for Human CNIH-1
    Protein for Human CNIH-1
    Protein for Human CNIH-1
    Protein for Human CNIH-1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      Plisov S.Y. , Ivanov S.V. , Lerman M. , Perantoni A.O.
      Submitted (1998-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Carcinoma.
    2. 2.
      "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells."
      Zhang Q.-H. , Ye M. , Wu X.-Y. , Ren S.-X. , Zhao M. , Zhao C.-J. , Fu G. , Shen Y. , Fan H.-Y. , Lu G. , Zhong M. , Xu X.-R. , Han Z.-G. , Zhang J.-W. , Tao J. , Huang Q.-H. , Zhou J. , Hu G.-X. , more...
      Genome Res.10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Umbilical cord blood.
    3. 3.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "The DNA sequence and analysis of human chromosome 14."
      Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
      Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Pancreas.
    6. 6.
      "The human homolog of Drosophila cornichon protein is differentially expressed in alloactivated T-cells."
      Utku N. , Bulwin G.-C. , Beinke S. , Heinemann T. , Beato F. , Randall J. , Schnieders B. , Sandhoff K. , Volk H.-D. , Milford E. , Gullans S.R.
      Biochim. Biophys. Acta1449:203-210(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 11-144
    7. 7.
      "Cornichon regulates transport and secretion of TGFalpha-related proteins in metazoan cells."
      Perez Castro C. , Piscopo D. , Nakagawa T. , Derynck R.
      J. Cell Sci.120:2454-2466(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH AREG AND TGFA;SUBCELLULAR LOCATION
    8. 8.
      "Upregulation of cornichon transcripts in the dorsolateral prefrontal cortex in schizophrenia."
      Drummond J.B. , Simmons M. , Haroutunian V. , Meador-Woodruff J.H.
      NeuroReport23:1031-1034(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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