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Index > Protein center > CNKSR1(Gene name) > Human
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  • CNKSR1 (Gene name),
  • Connector enhancer of kinase suppressor of ras 1 (Protein name ),  CNKR1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CNKSR1(CNK1);
    Protein name:
    Connector enhancer of kinase suppressor of ras 1(Connector enhancer of KSR 1);
    Alternative:
    Connector enhancer of KSR-like;CNK homolog protein 1(CNK1;hCNK1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with RHO and RALGDS.
    Function:
    May function as an adapter protein or regulator of Ras signaling pathways.
    Subcellular Location:
    Cytoplasm Membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    720
    Sequence:
    50:
    MEPVETWTPG | KVATWLRGLD | DSLQDYPFED | WQLPGKNLLQ | LCPQSLEALA | 
    100:
    VRSLGHQELI | LGGVEQLQAL | SSRLQTENLQ | SLTEGLLGAT | HDFQSIVQGC | 
    150:
    LGDCAKTPID | VLCAAVELLH | EADALLFWLS | RYLFSHLNDF | SACQEIRDLL | 
    200:
    EELSQVLHED | GPAAEKEGTV | LRICSHVAGI | CHNILVCCPK | ELLEQKAVLE | 
    250:
    QVQLDSPLGL | EIHTTSNCQH | FVSQVDTQVP | TDSRLQIQPG | DEVVQINEQV | 
    300:
    VVREERDMVG | WPRKNMVREL | LREPAGLSLV | LKKIPIPETP | PQTPPQVLDS | 
    350:
    PHQRSPSLSL | APLSPRAPSE | DVFAFDLSSN | PSPGPSPAWT | DSASLGPEPL | 
    400:
    PIPPEPPAIL | PAGVAGTPGL | PESPDKSPVG | RKKSKGLATR | LSRRRVSCRE | 
    450:
    LGRPDCDGWL | LLRKAPGGFM | GPRWRRRWFV | LKGHTLYWYR | QPQDEKAEGL | 
    500:
    INVSNYSLES | GHDQKKKYVF | QLTHDVYKPF | IFAADTLTDL | SMWVRHLITC | 
    550:
    ISKYQSPGRA | PPPREEDCYS | ETEAEDPDDE | AGSHSASPSP | AQAGSPLHGD | 
    600:
    TSPAATPTQR | SPRTSFGSLT | DSSEEALEGM | VRGLRQGGVS | LLGQPQPLTQ | 
    650:
    EQWRSSFMRR | NRDPQLNERV | HRVRALQSTL | KAKLQELQVL | EEVLGDPELT | 
    700:
    GEKFRQWKEQ | NRELYSEGLG | AWGVAQAEGS | SHILTSDSTE | QSPHSLPSDP | 
    720:
    EEHSHLCPLT | SESSLRPPDL | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    MIM:
    UniGene:
    SMR:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Connector enhancer of KSR 1
    CLIA Kit for Human Connector enhancer of KSR 1
    Polyclonal Antibody for Human Connector enhancer of KSR 1
    Monoclonal Antibody for Human Connector enhancer of KSR 1
    Protein for Human Connector enhancer of KSR 1

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "CNK, a RAF-binding multidomain protein required for RAS signaling."
      Therrien M. , Wong A.M. , Rubin G.M.
      Cell95:343-353(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Neuroepithelium.
    2. 2.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    3. 3.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Placenta.
    6. 6.
      "Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways."
      Jaffe A.B. , Aspenstroem P. , Hall A.
      Mol. Cell. Biol.24:1736-1746(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RHO AND RALGDS;MUTAGENESIS OF TRP-493
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-314;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 8.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-314;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      "Solution structure of the SAM domain of human connector enhancer of KSR-like protein CNK1."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2005-07) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1-78
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