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Index > Protein center > CNKSR2(Gene name) > Human
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  • CNKSR2 (Gene name),
  • Connector enhancer of kinase suppressor of ras 2 (Protein name ),  CNKR2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CNKSR2(CNK2;KIAA0902;KSR2);
    Protein name:
    Connector enhancer of kinase suppressor of ras 2(Connector enhancer of KSR 2);
    Alternative:
    CNK homolog protein 2(CNK2);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with RAF1, RAB2L and RAL GTPase proteins.
    Function:
    May function as an adapter protein or regulator of Ras signaling pathways.
    Subcellular Location:
    Cytoplasm Membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    1034
    Sequence:
    50:
    MALIMEPVSK | WSPSQVVDWM | KGLDDCLQQY | IKNFEREKIS | GDQLLRITHQ | 
    100:
    ELEDLGVSRI | GHQELILEAV | DLLCALNYGL | ETENLKTLSH | KLNASAKNLQ | 
    150:
    NFITGRRRSG | HYDGRTSRKL | PNDFLTSVVD | LIGAAKSLLA | WLDRSPFAAV | 
    200:
    TDYSVTRNNV | IQLCLELTTI | VQQDCTVYET | ENKILHVCKT | LSGVCDHIIS | 
    250:
    LSSDPLVSQS | AHLEVIQLAN | IKPSEGLGMY | IKSTYDGLHV | ITGTTENSPA | 
    300:
    DRCKKIHAGD | EVIQVNHQTV | VGWQLKNLVN | ALREDPSGVI | LTLKKRPQSM | 
    350:
    LTSAPALLKN | MRWKPLALQP | LIPRSPTSSV | ATPSSTISTP | TKRDSSALQD | 
    400:
    LYIPPPPAEP | YIPRDEKGNL | PCEDLRGHMV | GKPVHKGSES | PNSFLDQEYR | 
    450:
    KRFNIVEEDT | VLYCYEYEKG | RSSSQGRRES | TPTYGKLRPI | SMPVEYNWVG | 
    500:
    DYEDPNKMKR | DSRRENSLLR | YMSNEKIAQE | EYMFQRNSKK | DTGKKSKKKG | 
    550:
    DKSNSPTHYS | LLPSLQMDAL | RQDIMGTPVP | ETTLYHTFQQ | SSLQHKSKKK | 
    600:
    NKGPIAGKSK | RRISCKDLGR | GDCEGWLWKK | KDAKSYFSQK | WKKYWFVLKD | 
    650:
    ASLYWYINEE | DEKAEGFISL | PEFKIDRASE | CRKKYAFKAC | HPKIKSFYFA | 
    700:
    AEHLDDMNRW | LNRINMLTAG | YAERERIKQE | QDYWSESDKE | EADTPSTPKQ | 
    750:
    DSPPPPYDTY | PRPPSMSCAS | PYVEAKHSRL | SSTETSQSQS | SHEEFRQEVT | 
    800:
    GSSAVSPIRK | TASQRRSWQD | LIETPLTSSG | LHYLQTLPLE | DSVFSDSAAI | 
    850:
    SPEHRRQSTL | PTQKCHLQDH | YGPYPLAESE | RMQVLNGNGG | KPRSFTLPRD | 
    900:
    SGFNHCCLNA | PVSACDPQDD | VQPPEVEEEE | EEEEEEGEAA | GENIGEKSES | 
    950:
    REEKLGDSLQ | DLYRALEQAS | LSPLGEHRIS | TKMEYKLSFI | KRCNDPVMNE | 
    1000:
    KLHRLRILKS | TLKAREGEVA | IIDKVLDNPD | LTSKEFQQWK | QMYLDLFLDI | 
    1034:
    CQNTTSNDPL | SISSEVDVIT | SSLAHTHSYI | ETHV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    MIM:
    KEGG:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Connector enhancer of KSR 2
    ELISA Kit for Human Connector enhancer of KSR 2
    ELISA Kit for Human Connector enhancer of KSR 2
    CLIA Kit for Human Connector enhancer of KSR 2
    CLIA Kit for Human Connector enhancer of KSR 2
    CLIA Kit for Human Connector enhancer of KSR 2
    Polyclonal Antibody for Human Connector enhancer of KSR 2
    Polyclonal Antibody for Human Connector enhancer of KSR 2
    Polyclonal Antibody for Human Connector enhancer of KSR 2
    Monoclonal Antibody for Human Connector enhancer of KSR 2
    Monoclonal Antibody for Human Connector enhancer of KSR 2
    Monoclonal Antibody for Human Connector enhancer of KSR 2
    Protein for Human Connector enhancer of KSR 2
    Protein for Human Connector enhancer of KSR 2
    Protein for Human Connector enhancer of KSR 2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf."
      Lanigan T.M. , Liu A. , Huang Y.Z. , Mei L. , Margolis B. , Guan K.-L.
      FASEB J.17:2048-2060(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);FUNCTION;INTERACTION WITH RAF1; RAB2L AND RAL GTPASE PROTEINS;PHOSPHORYLATION
      tissue: Fetal brain.
    2. 2.
      "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Ishikawa K. , Suyama M. , Kikuno R. , Hirosawa M. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
      DNA Res.5:355-364(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Brain.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Brain.
    4. 4.
      "The DNA sequence of the human X chromosome."
      Ross M.T. , Grafham D.V. , Coffey A.J. , Scherer S. , McLay K. , Muzny D. , Platzer M. , Howell G.R. , Burrows C. , Bird C.P. , Frankish A. , Lovell F.L. , Howe K.L. , Ashurst J.L. , Fulton R.S. , Sudbrak R. , Wen G. , Jones M.C. , more...
      Nature434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 4)
      tissue: Brain.
      tissue: Testis.
    7. 7.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-908;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    8. 8.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-908;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      "Solution structure of the N-terminal SAM-domain of human KIAA0902 protein (connector enhancer of kinase suppressor of RAS 2)."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2007-07) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 8-79
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] HIS-46
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