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Index > Protein center > CNOT11(Gene name) > Human
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  • CNOT11 (Gene name),
  • CCR4-NOT transcription complex subunit 11 (Protein name ),  CNO11_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CNOT11(C40;C2orf29);
    Protein name:
    CCR4-NOT transcription complex subunit 11;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Component of the CCR4-NOT complex; distinct complexes seem to exist that differ in the participation of probably mutually exclusive catalytic subunits. CNOT10 and CNOT11 form a subcomplex docked to the CNOT1 scaffold.
    Function:
    Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function.
    Subcellular Location:
    Cytoplasm Nucleus
    Protein Attributes:
    Sequence length:
    510
    Sequence:
    50:
    MPGGGASAAS | GRLLTAAEQR | GSREAAGSAS | RSGFGGSGGG | RGGASGPGSG | 
    100:
    SGGPGGPAGR | MSLTPKELSS | LLSIISEEAG | GGSTFEGLST | AFHHYFSKAD | 
    150:
    HFRLGSVLVM | LLQQPDLLPS | AAQRLTALYL | LWEMYRTEPL | AANPFAASFA | 
    200:
    HLLNPAPPAR | GGQEPDRPPL | SGFLPPITPP | EKFFLSQLML | APPRELFKKT | 
    250:
    PRQIALMDVG | NMGQSVDISG | LQLALAERQS | ELPTQSKASF | PSILSDPDPD | 
    300:
    SSNSGFDSSV | ASQITEALVS | GPKPPIESHF | RPEFIRPPPP | LHICEDELAW | 
    350:
    LNPTEPDHAI | QWDKSMCVKN | STGVEIKRIM | AKAFKSPLSS | PQQTQLLGEL | 
    400:
    EKDPKLVYHI | GLTPAKLPDL | VENNPLVAIE | MLLKLMQSSQ | ITEYFSVLVN | 
    450:
    MDMSLHSMEV | VNRLTTAVDL | PPEFIHLYIS | NCISTCEQIK | DKYMQNRLVR | 
    500:
    LVCVFLQSLI | RNKIINVQDL | FIEVQAFCIE | FSRIREAAGL | FRLLKTLDTG | 
    510:
    ETPSETKMSK | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human CCR4-NOT transcription complex subunit 11
    ELISA Kit for Human CCR4-NOT transcription complex subunit 11
    ELISA Kit for Human CCR4-NOT transcription complex subunit 11
    CLIA Kit for Human CCR4-NOT transcription complex subunit 11
    CLIA Kit for Human CCR4-NOT transcription complex subunit 11
    CLIA Kit for Human CCR4-NOT transcription complex subunit 11
    Polyclonal Antibody for Human CCR4-NOT transcription complex subunit 11
    Polyclonal Antibody for Human CCR4-NOT transcription complex subunit 11
    Polyclonal Antibody for Human CCR4-NOT transcription complex subunit 11
    Monoclonal Antibody for Human CCR4-NOT transcription complex subunit 11
    Monoclonal Antibody for Human CCR4-NOT transcription complex subunit 11
    Monoclonal Antibody for Human CCR4-NOT transcription complex subunit 11
    Protein for Human CCR4-NOT transcription complex subunit 11
    Protein for Human CCR4-NOT transcription complex subunit 11
    Protein for Human CCR4-NOT transcription complex subunit 11

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Identification of differentially expressed genes associated with HER-2/neu overexpression in human breast cancer cells."
      Oh J.J. , Grosshans D.R. , Wong S.G. , Slamon D.J.
      Nucleic Acids Res.27:4008-4017(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Mammary gland.
    2. 2.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
      tissue: Colon.
    4. 4.
      "Human Ccr4-Not complexes contain variable deadenylase subunits."
      Lau N.C. , Kolkman A. , van Schaik F.M. , Mulder K.W. , Pijnappel W.W. , Heck A.J. , Timmers H.T.
      Biochem. J.422:443-453(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE CCR4-NOT COMPLEX;COMPOSITION OF THE CCR4-NOT COMPLEX
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    6. 6.
      "C2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complex."
      Mauxion F. , Preve B. , Seraphin B.
      RNA Biol.10:267-276(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE CCR4-NOT COMPLEX
    7. 7.
      "NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domain."
      Bawankar P. , Loh B. , Wohlbold L. , Schmidt S. , Izaurralde E.
      RNA Biol.10:228-244(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CNOT1 AND CNOT10
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