Gene name:
CNTNAP1 (CASPR;NRXN4) ;
Protein name:
Contactin-associated protein 1 (Caspr;Caspr1) ;
Alternative:
Neurexin-4 ;Neurexin IV ;p190 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with contactin in cis form.
Function:
Seems to play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the paranodal region of the axo-glial junction. In association with contactin may have a role in the signaling between axons and myelinating glial cells.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MMHLRLFCIL | LAAVSGAEGW | GYYGCDEELV | GPLYARSLGA | SSYYSLLTAP |
100:
RFARLHGISG | WSPRIGDPNP | WLQIDLMKKH | RIRAVATQGS | FNSWDWVTRY |
150:
MLLYGDRVDS | WTPFYQRGHN | STFFGNVNES | AVVRHDLHFH | FTARYIRIVP |
200:
LAWNPRGKIG | LRLGLYGCPY | KADILYFDGD | DAISYRFPRG | VSRSLWDVFA |
250:
FSFKTEEKDG | LLLHAEGAQG | DYVTLELEGA | HLLLHMSLGS | SPIQPRPGHT |
300:
TVSAGGVLND | QHWHYVRVDR | FGRDVNFTLD | GYVQRFILNG | DFERLNLDTE |
350:
MFIGGLVGAA | RKNLAYRHNF | RGCIENVIFN | RVNIADLAVR | RHSRITFEGK |
400:
VAFRCLDPVP | HPINFGGPHN | FVQVPGFPRR | GRLAVSFRFR | TWDLTGLLLF |
450:
SRLGDGLGHV | ELTLSEGQVN | VSIAQSGRKK | LQFAAGYRLN | DGFWHEVNFV |
500:
AQENHAVISI | DDVEGAEVRV | SYPLLIRTGT | SYFFGGCPKP | ASRWDCHSNQ |
550:
TAFHGCMELL | KVDGQLVNLT | LVEGRRLGFY | AEVLFDTCGI | TDRCSPNMCE |
600:
HDGRCYQSWD | DFICYCELTG | YKGETCHTPL | YKESCEAYRL | SGKTSGNFTI |
650:
DPDGSGPLKP | FVVYCDIREN | RAWTVVRHDR | LWTTRVTGSS | MERPFLGAIQ |
700:
YWNASWEEVS | ALANASQHCE | QWIEFSCYNS | RLLNTAGGYP | YSFWIGRNEE |
750:
QHFYWGGSQP | GIQRCACGLD | RSCVDPALYC | NCDADQPQWR | TDKGLLTFVD |
800:
HLPVTQVVIG | DTNRSTSEAQ | FFLRPLRCYG | DRNSWNTISF | HTGAALRFPP |
850:
IRANHSLDVS | FYFRTSAPSG | VFLENMGGPY | CQWRRPYVRV | ELNTSRDVVF |
900:
AFDVGNGDEN | LTVHSDDFEF | NDDEWHLVRA | EINVKQARLR | VDHRPWVLRP |
950:
MPLQTYIWME | YDQPLYVGSA | ELKRRPFVGC | LRAMRLNGVT | LNLEGRANAS |
1000:
EGTSPNCTGH | CAHPRLPCFH | GGRCVERYSY | YTCDCDLTAF | DGPYCNHDIG |
1050:
GFFEPGTWMR | YNLQSALRSA | AREFSHMLSR | PVPGYEPGYI | PGYDTPGYVP |
1100:
GYHGPGYRLP | DYPRPGRPVP | GYRGPVYNVT | GEEVSFSFST | SSAPAVLLYV |
1150:
SSFVRDYMAV | LIKDDGTLQL | RYQLGTSPYV | YQLTTRPVTD | GQPHSINITR |
1200:
VYRNLFIQVD | YFPLTEQKFS | LLVDSQLDSP | KALYLGRVME | TGVIDPEIQR |
1250:
YNTPGFSGCL | SGVRFNNVAP | LKTHFRTPRP | MTAELAEALR | VQGELSESNC |
1300:
GAMPRLVSEV | PPELDPWYLP | PDFPYYHDEG | WVAILLGFLV | AFLLLGLVGM |
1350:
LVLFYLQNHR | YKGSYHTNEP | KAAHEYHPGS | KPPLPTSGPA | QVPTPTAAPN |
1384:
QAPASAPAPA | PTPAPAPGPR | DQNLPQILEE | SRSE
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Human Caspr
ELISA Kit for Human Caspr
ELISA Kit for Human Caspr
Polyclonal Antibody for Human Caspr
Polyclonal Antibody for Human Caspr
Polyclonal Antibody for Human Caspr
Monoclonal Antibody for Human Caspr
Monoclonal Antibody for Human Caspr
Monoclonal Antibody for Human Caspr
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH CONTACTIN
tissue :
Neuroblastoma .