Gene name:
Cntnap1 (Caspr;Nrxn4) ;
Protein name:
Contactin-associated protein 1 (Caspr;Caspr1) ;
Alternative:
Neurexin-4 ;Neurexin IV ;p190 ;Paranodin ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with contactin in cis form.
Function:
Seems to play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the paranodal region of the axo-glial junction. In association with contactin may have a role in the signaling between axons and myelinating glial cells.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MMSLRLFSIL | LAAVVSGAQG | WGYYGCNEEL | VGPLYARSLG | ASSYYGLFTT |
100:
ARFARLHGIS | GWSPRIGDPN | PWLQIDLMKK | HRIRAVATQG | AFNSWDWVTR |
150:
YMLLYGDRVD | SWTPFYQQGH | NATFFGNVND | SAVVRHDLHY | HFTARYIRIV |
200:
PLAWNPRGKI | GLRLGIYGCP | YTSNILYFDG | DDAISYRFQR | GASQSLWDVF |
250:
AFSFKTEEKD | GLLLHTEGSQ | GDYVTLELQG | AHLLLHMSLG | SSPIQPRPGH |
300:
TTVSAGGVLN | DLSWHYVRVD | RYGREANLTL | DGYVHRFVLN | GDFERLNLEN |
350:
EIFIGGLVGA | ARKNLAYRHN | FRGCIENVIY | NRINIAEMAV | QRHSRITFEG |
400:
NVAFRCLDPV | PHPINFGGPH | NFVQVPGFPR | RGRLAVSFRF | RTWDLTGLLL |
450:
FSRLGDGLGH | VELMLSEGQV | NVSIAQTGRK | KLQFAAGYRL | NDGFWHEVNF |
500:
VAQENHAVIS | IDDVEGAEVR | VSYPLLIRTG | TSYFFGGCPK | PASRWGCHSN |
550:
QTAFHGCMEL | LKVDGQLVNL | TLVEFRKLGY | FAEVLFDTCG | ITDRCSPNMC |
600:
EHDGRCYQSW | DDFICYCELT | GYKGVTCHEP | LYKESCEAYR | LSGKYSGNYT |
650:
IDPDGSGPLK | PFVVYCDIRE | NRAWTVVRHD | RLWTTRVTGS | SMDRPFLGAI |
700:
QYWNASWEEV | SALANASQHC | EQWIEFSCYN | SRLLNTAGGY | PYSFWIGRNE |
750:
EQHFYWGGSQ | PGIQRCACGL | DQSCIDPALH | CNCDADQPQW | RTDKGLLTFV |
800:
DHLPVTQVVI | GDTNRSSSEA | QFFLRPLRCY | GDRNSWNTIS | FRTGAALRFP |
850:
PIRANHSLDV | SFYFRTSAPS | GVFLENMGGP | FCQWRRPYVR | VELNTSRDVV |
900:
FAFDIGNGDE | NLTVHSDDFE | FNDDEWHLVR | AEINVKQARL | RVDHRPWVLR |
950:
PMPLQTYIWL | EYDQPLYVGS | AELKRRPFVG | CLRAMRLNGV | TLNLEGRANA |
1000:
SEGTFPNCTG | HCTHPRFPCF | HGGRCVERYS | YYTCDCDLTA | FDGPYCNHDI |
1050:
GGFFETGTWM | RYNLQSALRS | AAQEFSHMLS | RPVPGYEPGY | IPGYDTPGYV |
1100:
PGYHGPGYRL | PDYPRPGRPV | PGYRGPVYNV | TGEEVSFSFS | TSSAPAVLLY |
1150:
VSSFVRDYMA | VLIKEDGTLQ | LRYQLGTSPY | VYQLTTRPVT | DGQPHSVNIT |
1200:
RVYRNLFIQV | DYFPLTEQKF | SLLVDSQLDS | PKALYLGRVM | ETGVIDPEIQ |
1250:
RYNTPGFSGC | LSGVRFNNVA | PLKTHFRTPR | PMTAELAEAM | RVQGELSESN |
1300:
CGAMPRLVSE | VPPELDPWYL | PPDFPYYHDD | GWIAILLGFL | VAFLLLGLVG |
1350:
MLVLFYLQNH | RYKGSYHTNE | PKATHDSHPG | GKAPLPPSGP | AQAPAPTPAP |
1381:
TQVPTPAPAP | ASGPGPRDQN | LPQILEESRS | E
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Polyclonal Antibody for Rat Caspr
Polyclonal Antibody for Rat Caspr
Polyclonal Antibody for Rat Caspr
Monoclonal Antibody for Rat Caspr
Monoclonal Antibody for Rat Caspr
Monoclonal Antibody for Rat Caspr
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH CONTACTIN
tissue :
Pituitary tumor .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Sprague-Dawley .
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CHARACTERIZATION
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY