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Index > Protein center > Cntnap1(Gene name) > Rat
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  • Cntnap1 (Gene name),
  • Contactin-associated protein 1 (Protein name ),  CNTP1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Cntnap1(Caspr;Nrxn4);
    Protein name:
    Contactin-associated protein 1(Caspr;Caspr1);
    Alternative:
    Neurexin-4;Neurexin IV;p190;Paranodin;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with contactin in cis form.
    Function:
    Seems to play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the paranodal region of the axo-glial junction. In association with contactin may have a role in the signaling between axons and myelinating glial cells.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    1381
    Sequence:
    50:
    MMSLRLFSIL | LAAVVSGAQG | WGYYGCNEEL | VGPLYARSLG | ASSYYGLFTT | 
    100:
    ARFARLHGIS | GWSPRIGDPN | PWLQIDLMKK | HRIRAVATQG | AFNSWDWVTR | 
    150:
    YMLLYGDRVD | SWTPFYQQGH | NATFFGNVND | SAVVRHDLHY | HFTARYIRIV | 
    200:
    PLAWNPRGKI | GLRLGIYGCP | YTSNILYFDG | DDAISYRFQR | GASQSLWDVF | 
    250:
    AFSFKTEEKD | GLLLHTEGSQ | GDYVTLELQG | AHLLLHMSLG | SSPIQPRPGH | 
    300:
    TTVSAGGVLN | DLSWHYVRVD | RYGREANLTL | DGYVHRFVLN | GDFERLNLEN | 
    350:
    EIFIGGLVGA | ARKNLAYRHN | FRGCIENVIY | NRINIAEMAV | QRHSRITFEG | 
    400:
    NVAFRCLDPV | PHPINFGGPH | NFVQVPGFPR | RGRLAVSFRF | RTWDLTGLLL | 
    450:
    FSRLGDGLGH | VELMLSEGQV | NVSIAQTGRK | KLQFAAGYRL | NDGFWHEVNF | 
    500:
    VAQENHAVIS | IDDVEGAEVR | VSYPLLIRTG | TSYFFGGCPK | PASRWGCHSN | 
    550:
    QTAFHGCMEL | LKVDGQLVNL | TLVEFRKLGY | FAEVLFDTCG | ITDRCSPNMC | 
    600:
    EHDGRCYQSW | DDFICYCELT | GYKGVTCHEP | LYKESCEAYR | LSGKYSGNYT | 
    650:
    IDPDGSGPLK | PFVVYCDIRE | NRAWTVVRHD | RLWTTRVTGS | SMDRPFLGAI | 
    700:
    QYWNASWEEV | SALANASQHC | EQWIEFSCYN | SRLLNTAGGY | PYSFWIGRNE | 
    750:
    EQHFYWGGSQ | PGIQRCACGL | DQSCIDPALH | CNCDADQPQW | RTDKGLLTFV | 
    800:
    DHLPVTQVVI | GDTNRSSSEA | QFFLRPLRCY | GDRNSWNTIS | FRTGAALRFP | 
    850:
    PIRANHSLDV | SFYFRTSAPS | GVFLENMGGP | FCQWRRPYVR | VELNTSRDVV | 
    900:
    FAFDIGNGDE | NLTVHSDDFE | FNDDEWHLVR | AEINVKQARL | RVDHRPWVLR | 
    950:
    PMPLQTYIWL | EYDQPLYVGS | AELKRRPFVG | CLRAMRLNGV | TLNLEGRANA | 
    1000:
    SEGTFPNCTG | HCTHPRFPCF | HGGRCVERYS | YYTCDCDLTA | FDGPYCNHDI | 
    1050:
    GGFFETGTWM | RYNLQSALRS | AAQEFSHMLS | RPVPGYEPGY | IPGYDTPGYV | 
    1100:
    PGYHGPGYRL | PDYPRPGRPV | PGYRGPVYNV | TGEEVSFSFS | TSSAPAVLLY | 
    1150:
    VSSFVRDYMA | VLIKEDGTLQ | LRYQLGTSPY | VYQLTTRPVT | DGQPHSVNIT | 
    1200:
    RVYRNLFIQV | DYFPLTEQKF | SLLVDSQLDS | PKALYLGRVM | ETGVIDPEIQ | 
    1250:
    RYNTPGFSGC | LSGVRFNNVA | PLKTHFRTPR | PMTAELAEAM | RVQGELSESN | 
    1300:
    CGAMPRLVSE | VPPELDPWYL | PPDFPYYHDD | GWIAILLGFL | VAFLLLGLVG | 
    1350:
    MLVLFYLQNH | RYKGSYHTNE | PKATHDSHPG | GKAPLPPSGP | AQAPAPTPAP | 
    1381:
    TQVPTPAPAP | ASGPGPRDQN | LPQILEESRS | E
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Caspr
    ELISA Kit for Rat Caspr
    ELISA Kit for Rat Caspr
    CLIA Kit for Rat Caspr
    CLIA Kit for Rat Caspr
    CLIA Kit for Rat Caspr
    Polyclonal Antibody for Rat Caspr
    Polyclonal Antibody for Rat Caspr
    Polyclonal Antibody for Rat Caspr
    Monoclonal Antibody for Rat Caspr
    Monoclonal Antibody for Rat Caspr
    Monoclonal Antibody for Rat Caspr
    Protein for Rat Caspr
    Protein for Rat Caspr
    Protein for Rat Caspr

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions."
      Peles E. , Nativ M. , Lustig M. , Grumet M. , Schilling J. , Martinez R. , Plowman G.D. , Schlessinger J.
      EMBO J.16:978-988(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH CONTACTIN
      tissue: Pituitary tumor.
    2. 2.
      "Paranodin, a glycoprotein of neuronal paranodal membranes."
      Menegoz M. , Gaspar P. , Le Bert M. , Galvez T. , Burgaya F. , Palfrey C. , Ezan P. , Arnos F. , Girault J.-A.
      Neuron19:319-331(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Brain.
    3. 3.
      "The axonal membrane protein Caspr, a homologue of neurexin IV, is a component of the septate-like paranodal junctions that assemble during myelination."
      Einheber S. , Zanazzi G. , Ching W. , Scherer S. , Milner T.A. , Peles E. , Salzer J.L.
      J. Cell Biol.139:1495-1506(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
    4. 4.
      "Internodal specializations of myelinated axons in the central nervous system."
      Arroyo E.J. , Xu T. , Poliak S. , Watson M. , Peles E. , Scherer S.S.
      Cell Tissue Res.305:53-66(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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