Col8a2 ELISA Kit for Mouse(Mus musculus) | EIAab.comCol8a2 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Col8a2(Gene name) > Mouse

Col8a2 (Gene name),

Collagen alpha-2(VIII) chain (Protein name ), CO8A2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Col8a2;

Protein name:

Collagen alpha-2(VIII) chain;

Alternative:

Endothelial collagen;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homotrimers, or heterotrimers in association with alpha 2(VIII) type collagens. Four homotrimers can form a tetrhedron stabilized by central interacting C-terminal NC1 trimers.

Function:

Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in artherogenesis.

Subcellular Location:

Secreted extracellular space extracellular matrix basement membrane

Protein Attributes:

Sequence length:

699

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

699:

YLDQASGGAV | LQLRPNDQVW | VQMPSDQANG | LYSTEYIHSS | FSGFLLCPT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:329941

Pfam:

PF00386

UniGene:

Mm.296327

String:

P25318

SMR:

P25318

Uniprot:

P25318

FOR

ELISA Kit for Mouse Collagen alpha-2(VIII) chain

CLIA Kit for Mouse Collagen alpha-2(VIII) chain

Polyclonal Antibody for Mouse Collagen alpha-2(VIII) chain

Monoclonal Antibody for Mouse Collagen alpha-2(VIII) chain

Protein for Mouse Collagen alpha-2(VIII) chain

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain: C57BL/6.
tissue: Brain.
3.

"Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Kitamura H. , Nakagawa T. , Nagase T. , Ohara O. , Koga H.
DNA Res.11:127-135(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 60-699 (ISOFORM 1)
tissue: Embryonic tail.
4.

"The alpha 2(VIII) collagen gene. A novel member of the short chain collagen family located on the human chromosome 1."
Muragaki Y. , Jacenko O. , Apte S. , Mattei M.-G. , Ninomiya Y. , Olsen B.R.
J. Biol. Chem.266:7721-7727(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 530-699
5.

"Lack of type VIII collagen in mice ameliorates diabetic nephropathy."
Hopfer U. , Hopfer H. , Meyer-Schwesinger C. , Loeffler I. , Fukai N. , Olsen B.R. , Stahl R.A. , Wolf G.
Diabetes58:1672-1681(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;DISRUPTION PHENOTYPE;FUNCTION

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