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Index > Protein center > COA1(Gene name) > Human
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  • COA1 (Gene name),
  • Cytochrome c oxidase assembly factor 1 homolog (Protein name ),  COA1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    COA1(C7orf44;MITRAC15);
    Protein name:
    Cytochrome c oxidase assembly factor 1 homolog;
    Alternative:
    Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with COX17 and COA6. Component of some MITRAC complex.
    Function:
    Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for assembly of mitochondrial respiratory chain complex I and complex IV.
    Subcellular Location:
    Mitochondrion inner membrane Single-pass membrane protein
    Protein Attributes:
    Sequence length:
    146
    Sequence:
    50:
    MMWQKYAGSR | RSMPLGARIL | FHGVFYAGGF | AIVYYLIQKF | HSRALYYKLA | 
    100:
    VEQLQSHPEA | QEALGPPLNI | HYLKLIDREN | FVDIVDAKLK | IPVSGSKSEG | 
    146:
    LLYVHSSRGG | PFQRWHLDEV | FLELKDGQQI | PVFKLSGENG | DEVKKE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    KEGG:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Cytochrome c oxidase assembly factor 1 homolog
    CLIA Kit for Human Cytochrome c oxidase assembly factor 1 homolog
    Polyclonal Antibody for Human Cytochrome c oxidase assembly factor 1 homolog
    Monoclonal Antibody for Human Cytochrome c oxidase assembly factor 1 homolog
    Protein for Human Cytochrome c oxidase assembly factor 1 homolog

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Embryo.
      tissue: Uterus.
    2. 2.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Skin.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    6. 6.
      "MITRAC links mitochondrial protein translocation to respiratory-chain assembly and translational regulation."
      Mick D.U. , Dennerlein S. , Wiese H. , Reinhold R. , Pacheu-Grau D. , Lorenzi I. , Sasarman F. , Weraarpachai W. , Shoubridge E.A. , Warscheid B. , Rehling P.
      Cell151:1528-1541(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;IDENTIFICATION IN SOME MITRAC COMPLEX;TOPOLOGY
    7. 7.
      "Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase."
      Szklarczyk R. , Wanschers B.F. , Cuypers T.D. , Esseling J.J. , Riemersma M. , van den Brand M.A. , Gloerich J. , Lasonder E. , van den Heuvel L.P. , Nijtmans L.G. , Huynen M.A.
      Genome Biol.13:RESEARCH0012.1-RESEARCH0012.14(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH COX17 AND COA6;SUBCELLULAR LOCATION
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