Protein name:
Collagen alpha-1(XII) chain ;
Alternative:
Fibrochimerin ;
Organism:
Chicken (Gallus gallus).
General Annotation
Sub Unit:
Trimer of identical chains each containing 190 kDa of non-triple-helical sequences.
Function:
Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix.
Subcellular Location:
Secreted
extracellular space
extracellular matrix
Protein Attributes:
50:
MRTALCSAVA | ALCAAALLSS | IEAEVNPPSD | LNFTIIDEHN | VQMSWKRPPD |
100:
AIVGYRITVV | PTNDGPTKEF | TLSPSTTQTV | LSDLIPEIEY | VVSIASYDEV |
150:
EESLPVFGQL | TIQTGGPGIP | EEKKVEAQIQ | KCSISAMTDL | VFLVDGSWSV |
200:
GRNNFRYILD | FMVALVSAFD | IGEEKTRVGV | VQYSSDTRTE | FNLNQYFRRS |
250:
DLLDAIKRIP | YKGGNTMTGE | AIDYLVKNTF | TESAGARKGF | PKVAIVITDG |
300:
KAQDEVEIPA | RELRNIGVEV | FSLGIKAADA | KELKLIASQP | SLKHVFNVAN |
350:
FDGIVDIQNE | IILQVCSGVD | EQLGELVSGE | EVVEPASNLV | ATQISSKSVR |
400:
ITWDPSTSQI | TGYRVQFIPM | IAGGKQHVLS | VGPQTTALNV | KDLSPDTEYQ |
450:
INVYAMKGLT | PSEPITIMEK | TQQVKVQVEC | SRGVDVKADV | VFLVDGSYSI |
500:
GIANFVKVRA | FLEVLVKSFE | ISPRKVQISL | VQYSRDPHME | FSLNRYNRVK |
550:
DIIQAINTFP | YRGGSTNTGK | AMTYVREKVF | VTSKGSRPNV | PRVMILITDG |
600:
KSSDAFKEPA | IKLRDADVEI | FAVGVKDAVR | TELEAIASPP | AETHVYTVED |
650:
FDAFQRISFE | LTQSVCLRIE | QELAAIRKKS | YVPAKNMVFS | DVTSDSFKVS |
700:
WSAAGSEEKS | YLIKYKVAIG | GDEFIVSVPA | SSTSSVLTNL | LPETTYAVSV |
750:
IAEYEDGDGP | PLDGEETTLE | VKGAPRNLRI | TDETTDSFIV | GWTPAPGNVL |
800:
RYRLVYRPLT | GGERRQVTVS | ANERSTTLRN | LIPDTRYEVS | VIAEYQSGPG |
850:
NALNGYAKTD | EVRGNPRNLR | VSDATTSTTM | KLSWSAAPGK | VQHVLYNLHT |
900:
RYAGVETKEL | TVKGDTTSKE | LKGLDEATRY | ALTVSALYAS | GAGEALSGEG |
950:
ETLEERGSPR | NLITTDITDT | TVGLSWTPAP | GTVNNYRIVW | KSLYDDTMGE |
1000:
KRVPGNTVDA | VLDGLEPETK | YRISIYAAYS | SGEGDPVEGE | AFTDVSQSAR |
1050:
TVTVDNETEN | TMRVSVAALT | WEGLVLARVL | PNRSGGRQMF | GKVNASATSI |
1100:
VLKRLKPRTT | YDLSVVPIYD | FGQGKSRKAE | GTTASPFKPP | RNLRTSDSTM |
1150:
SSFRVTWEPA | PGRVKGYKVT | FHPTEDDRNL | GELVVGPYDS | TVVLEELRAG |
1200:
TTYKVNVFGM | FDGGESNPLV | GQEMTTLSDT | TTEPFLSRGL | ECRTRAEADI |
1250:
VLLVDGSWSI | GRPNFKTVRN | FISRIVEVFD | IGPDKVQIGL | AQYSGDPRTE |
1300:
WNLNAYRTKE | ALLDAVTNLP | YKGGNTLTGM | ALDFILKNNF | KQEAGLRPRA |
1350:
RKIGVLITDG | KSQDDVVTPS | RRLRDEGVEL | YAIGIKNADE | NELKQIATDP |
1400:
DDIHAYNVAD | FSFLASIGED | VTTNLCNSVK | GPGDLPPPSN | LVISEVTPHS |
1450:
FRLRWSPPPE | SVDRYRVEYY | PTTGGPPKQF | YVSRMETTTV | LKDLTPETEY |
1500:
IVNVFSVVED | ESSEPLIGRE | ITYPLSSVRN | LNVYDIGSTS | MRVRWEPVNG |
1550:
ATGYLLTYEP | VNATVPTTEK | EMRVGPSVNE | VQLVDLIPNT | EYTLTAYVLY |
1600:
GDITSDPLTS | QEVTLPLPGP | RGVTIRDVTH | STMNVLWDPA | PGKVRKYIIR |
1650:
YKIADEADVK | EVEIDRLKTS | TTLTDLSSQR | LYNVKVVAVY | DEGESLPVVA |
1700:
SCYSAVPSPV | NLRITEITKN | SFRGTWDHGA | PDVSLYRITW | GPYGRSEKAE |
1750:
SIVNGDVNSL | LFENLNPDTL | YEVSVTAIYP | DESETVDDLI | GSERTLPLVP |
1800:
ITTPAPKSGP | RNLQVYNATS | HSLTVKWDPA | SGRVQRYKII | YQPINGDGPE |
1850:
QSTMVGGRQN | SVVIQKLQPD | TPYAITVSSM | YADGEGGRMT | GRGRTKPLTT |
1900:
VKNMLVYDPT | TSTLNVRWDH | AEGNPRQYKV | FYRPTAGGAE | EMTTVPGNTN |
1950:
YVILRSLEPN | TPYTVTVVPV | FPEGDGGRTT | DTGRTLERGT | PRNIQVYNPT |
2000:
PNSMNVRWEP | APGPVQQYRV | NYSPLSGPRP | SESIVVPANT | RDVMLERLTP |
2050:
DTAYSINVIA | LYADGEGNPS | QAQGRTLPRS | GPRNLRVFDE | TTNSLSVQWD |
2100:
HADGPVQQYR | IIYSPTVGDP | IDEYTTVPGI | RNNVILQPLQ | SDTPYKITVV |
2150:
AVYEDGDGGQ | LTGNGRTVGL | LPPQNIYITD | EWYTRFRVSW | DPSPSPVLGY |
2200:
KIVYKPVGSN | EPMEVFVGEV | TSYTLHNLSP | STTYDVNVYA | QYDSGMSIPL |
2250:
TDQGTTLYLN | VTDLTTYKIG | WDTFCIRWSP | HRSATSYRLK | LNPADGSRGQ |
2300:
EITVRGSETS | HCFTGLSPDT | EYNATVFVQT | PNLEGPPVSV | REHTVLKPTE |
2350:
APTPPPTPPP | PPTIPPARDV | CRGAKADIVF | LTDASWSIGD | DNFNKVVKFV |
2400:
FNTVGAFDLI | NPAGIQVSLV | QYSDEAQSEF | KLNTFDDKAQ | ALGALQNVQY |
2450:
RGGNTRTGKA | LTFIKEKVLT | WESGMRRGVP | KVLVVVTDGR | SQDEVRKAAT |
2500:
VIQHSGFSVF | VVGVADVDYN | ELAKIASKPS | ERHVFIVDDF | DAFEKIQDNL |
2550:
VTFVCETATS | TCPLIYLEGY | TSPGFKMLES | YNLTEKHFAS | VQGVSLESGS |
2600:
FPSYVAYRLH | KNAFVSQPIR | EIHPEGLPQA | YTIIMLFRLL | PESPSEPFAI |
2650:
WQITDRDYKP | QVGVVLDPGS | KVLSFFNKDT | RGEVQTVTFD | NDEVKKIFYG |
2700:
SFHKVHIVVT | SSNVKIYIDC | SEILEKPIKE | AGNITTDGYE | ILGKLLKGDR |
2750:
RSATLEIQNF | DIVCSPVWTS | RDRCCDLPSM | RDEAKCPALP | NACTCTQDSV |
2800:
GPPGPPGPPG | GPGAKGPRGE | RGLTGSSGPP | GPRGETGPPG | PQGPPGPQGP |
2850:
NGLQIPGEPG | RQGMKGDAGQ | PGLPGRSGTP | GLPGPPGPVG | PPGERGFTGK |
2900:
DGPTGPRGPP | GPAGAPGVPG | VAGPSGKPGK | PGDRGTPGTP | GMKGEKGDRG |
2950:
DIASQNMMRA | VARQVCEQLI | NGQMSRFNQM | LNQIPNDYYS | NRNQPGPPGP |
3000:
PGPPGAAGTR | GEPGPGGRPG | FPGPPGVQGP | PGERGMPGEK | GERGTGSQGP |
3050:
RGLPGPPGPQ | GESRTGPPGS | TGSRGPPGPP | GRPGNAGIRG | PPGPPGYCDS |
3100:
SQCASIPYNG | QGFPEPYVPE | SGPYQPEGEP | FIVPMESERR | EDEYEDYGVE |
3124:
MHSPEYPEHM | RWKRSLSRKA | KRKP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rabbit
Chicken
Human
Bovine
Rat
Mouse
ELISA Kit for Chicken Collagen alpha-1(XII) chain
ELISA Kit for Chicken Collagen alpha-1(XII) chain
ELISA Kit for Chicken Collagen alpha-1(XII) chain
ELISA Kit for Chicken Collagen alpha-1(XII) chain
ELISA Kit for Chicken Collagen alpha-1(XII) chain
ELISA Kit for Chicken Collagen alpha-1(XII) chain
CLIA Kit for Chicken Collagen alpha-1(XII) chain
CLIA Kit for Chicken Collagen alpha-1(XII) chain
CLIA Kit for Chicken Collagen alpha-1(XII) chain
CLIA Kit for Chicken Collagen alpha-1(XII) chain
CLIA Kit for Chicken Collagen alpha-1(XII) chain
CLIA Kit for Chicken Collagen alpha-1(XII) chain
Polyclonal Antibody for Chicken Collagen alpha-1(XII) chain
Polyclonal Antibody for Chicken Collagen alpha-1(XII) chain
Polyclonal Antibody for Chicken Collagen alpha-1(XII) chain
Polyclonal Antibody for Chicken Collagen alpha-1(XII) chain
Polyclonal Antibody for Chicken Collagen alpha-1(XII) chain
Polyclonal Antibody for Chicken Collagen alpha-1(XII) chain
Monoclonal Antibody for Chicken Collagen alpha-1(XII) chain
Monoclonal Antibody for Chicken Collagen alpha-1(XII) chain
Monoclonal Antibody for Chicken Collagen alpha-1(XII) chain
Monoclonal Antibody for Chicken Collagen alpha-1(XII) chain
Monoclonal Antibody for Chicken Collagen alpha-1(XII) chain
Monoclonal Antibody for Chicken Collagen alpha-1(XII) chain
Protein for Chicken Collagen alpha-1(XII) chain
Protein for Chicken Collagen alpha-1(XII) chain
Protein for Chicken Collagen alpha-1(XII) chain
Protein for Chicken Collagen alpha-1(XII) chain
Protein for Chicken Collagen alpha-1(XII) chain
Protein for Chicken Collagen alpha-1(XII) chain
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"The complete primary structure of type XII collagen shows a chimeric molecule with reiterated fibronectin type III motifs, von Willebrand factor A motifs, a domain homologous to a noncollagenous region of type IX collagen, and short collagenous domains with an Arg-Gly-Asp site."
Yamagata M.
,
Yamada K.M.
,
Yamada S.S.
,
Shinomura T.
,
Tanaka H.
,
Nishida Y.
,
Obara M.
,
Kimata K.
J. Cell Biol.115:209-221(1991)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG)
strain :
White leghorn .
tissue :
Embryonic fibroblast .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 2456-3124;PROTEIN SEQUENCE OF 2772-2794 AND 2846-2873
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 2960-3076
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-1283 (ISOFORM SHORT);ALTERNATIVE SPLICING
tissue :
Embryo .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ALTERNATIVE SPLICING