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Index > Protein center > COPG2(Gene name) > Human
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  • COPG2 (Gene name),
  • Coatomer subunit gamma-2 (Protein name ),  COPG2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    COPG2;
    Protein name:
    Coatomer subunit gamma-2;
    Alternative:
    Gamma-2-coat protein(Gamma-2-COP);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Oligomeric complex. Binds to CDC42.
    Function:
    The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
    Subcellular Location:
    Cytoplasm Golgi apparatus membrane Peripheral membrane protein Cytoplasmic side Cytoplasmic vesicle COPI-coated vesicle membrane Peripheral membrane protein Cytoplasmic side The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
    Protein Attributes:
    Sequence length:
    871
    Sequence:
    50:
    MIKKFDKKDE | ESGSGSNPFQ | HLEKSAVLQE | ARIFNETPIN | PRRCLHILTK | 
    100:
    ILYLLNQGEH | FGTTEATEAF | FAMTRLFQSN | DQTLRRMCYL | TIKEMATISE | 
    150:
    DVIIVTSSLT | KDMTGKEDVY | RGPAIRALCR | ITDGTMLQAI | ERYMKQAIVD | 
    200:
    KVSSVSSSAL | VSSLHMMKIS | YDVVKRWINE | AQEAASSDNI | MVQYHALGVL | 
    250:
    YHLRKNDRLA | VSKMLNKFTK | SGLKSQFAYC | MLIRIASRLL | KETEDGHESP | 
    300:
    LFDFIESCLR | NKHEMVIYEA | ASAIIHLPNC | TARELAPAVS | VLQLFCSSPK | 
    350:
    PALRYAAVRT | LNKVAMKHPS | AVTACNLDLE | NLITDSNRSI | ATLAITTLLK | 
    400:
    TGSESSVDRL | MKQISSFVSE | ISDEFKVVVV | QAISALCQKY | PRKHSVMMTF | 
    450:
    LSNMLRDDGG | FEYKRAIVDC | IISIVEENPE | SKEAGLAHLC | EFIEDCEHTV | 
    500:
    LATKILHLLG | KEGPRTPVPS | KYIRFIFNRV | VLENEAVRAA | AVSALAKFGA | 
    550:
    QNESLLPSIL | VLLQRCMMDT | DDEVRDRATF | YLNVLQQRQM | ALNATYIFNG | 
    600:
    LTVSVPGMEK | ALHQYTLEPS | EKPFDMKSIP | LAMAPVFEQK | AEITLVATKP | 
    650:
    EKLAPSRQDI | FQEQLAAIPE | FLNIGPLFKS | SEPVQLTEAE | TEYFVRCIKH | 
    700:
    MFTNHIVFQF | DCTNTLNDQL | LEKVTVQMEP | SDSYEVLSCI | PAPSLPYNQP | 
    750:
    GICYTLVRLP | DDDPTAVAGS | FSCTMKFTVR | DCDPNTGVPD | EDGYDDEYVL | 
    800:
    EDLEVTVSDH | IQKVLKPNFA | AAWEEVGDTF | EKEETFALSS | TKTLEEAVNN | 
    850:
    IITFLGMQPC | ERSDKVPENK | NSHSLYLAGI | FRGGYDLLVR | SRLALADGVT | 
    871:
    MQVTVRSKER | TPVDVILASV | G
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    Pfam:
    UniGene:
    SMR:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Coatomer subunit gamma-2
    ELISA Kit for Human Coatomer subunit gamma-2
    ELISA Kit for Human Coatomer subunit gamma-2
    ELISA Kit for Human Coatomer subunit gamma-2
    CLIA Kit for Human Coatomer subunit gamma-2
    CLIA Kit for Human Coatomer subunit gamma-2
    CLIA Kit for Human Coatomer subunit gamma-2
    CLIA Kit for Human Coatomer subunit gamma-2
    Polyclonal Antibody for Human Coatomer subunit gamma-2
    Polyclonal Antibody for Human Coatomer subunit gamma-2
    Polyclonal Antibody for Human Coatomer subunit gamma-2
    Polyclonal Antibody for Human Coatomer subunit gamma-2
    Monoclonal Antibody for Human Coatomer subunit gamma-2
    Monoclonal Antibody for Human Coatomer subunit gamma-2
    Monoclonal Antibody for Human Coatomer subunit gamma-2
    Monoclonal Antibody for Human Coatomer subunit gamma-2
    Protein for Human Coatomer subunit gamma-2
    Protein for Human Coatomer subunit gamma-2
    Protein for Human Coatomer subunit gamma-2
    Protein for Human Coatomer subunit gamma-2

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    Precision
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    Linearity
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    References
    1. 1.
      "Newly identified coatomer subunits reveal multiple copy complexes acting in the early secretory pathway."
      Whitney J.A. , Godzich M. , Kreis T.E.
      Submitted (1999-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Gamma2-COP, a novel imprinted gene on chromosome 7q32, defines a new imprinting cluster in the human genome."
      Blagitko N. , Schulz U. , Schinzel A.A. , Ropers H.-H. , Kalscheuer V.M.
      Hum. Mol. Genet.8:2387-2396(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Identification and characterization of novel isoforms of COP I subunits."
      Futatsumori M. , Kasai K. , Takatsu H. , Shin H.-W. , Nakayama K.
      J. Biochem.128:793-801(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    5. 5.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7-871 (ISOFORM 1)
      tissue: Brain.
      tissue: Eye.
    8. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH JAGN1
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