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Index > Protein center > COPRS(Gene name) > Bovine
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  • COPRS (Gene name),
  • Coordinator of PRMT5 and differentiation stimulator (Protein name ),  COPRS_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Vaild Sequence
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  • Gene name:
    COPRS(COPR5);
    Protein name:
    Coordinator of PRMT5 and differentiation stimulator;
    Alternative:
    Cooperator of PRMT5;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Interacts with PRMT5 (By similarity). Interacts with histone H4; specifically interacts with the N-terminus of histone H4 but not with histone H3 (By similarity). Interacts with CBFB (By similarity). Found in a complex with PRMT5, RUNX1 and CBFB.
    Function:
    Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression (By similarity). Plays a role in muscle cell differentiation by modulating the recruitment of PRMT5 to the promoter of genes involved in the coordination between cell cycle exit and muscle differentiation.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    185
    Sequence:
    50:
    MDPPTAGAQS | LGAAEQPRGL | QLPSGREAPP | SPGTAFAPAD | HSSQEKATEN | 
    100:
    ATDRLANGAQ | SIPHDSPAHG | EGTHCEEEGF | AEDDEDSDGE | PSPWELSEGM | 
    150:
    SGCLPKEQAG | DLFHEDWDLE | LKADQGNPYD | ADDIQGCLSQ | EVRPWVCCAP | 
    185:
    QGDMIYDPSW | HHPPPLIPHY | SKMVFETGQF | DDAED
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Coordinator of PRMT5 and differentiation stimulator
    ELISA Kit for Bovine Coordinator of PRMT5 and differentiation stimulator
    ELISA Kit for Bovine Coordinator of PRMT5 and differentiation stimulator
    CLIA Kit for Bovine Coordinator of PRMT5 and differentiation stimulator
    CLIA Kit for Bovine Coordinator of PRMT5 and differentiation stimulator
    CLIA Kit for Bovine Coordinator of PRMT5 and differentiation stimulator
    Polyclonal Antibody for Bovine Coordinator of PRMT5 and differentiation stimulator
    Polyclonal Antibody for Bovine Coordinator of PRMT5 and differentiation stimulator
    Polyclonal Antibody for Bovine Coordinator of PRMT5 and differentiation stimulator
    Monoclonal Antibody for Bovine Coordinator of PRMT5 and differentiation stimulator
    Monoclonal Antibody for Bovine Coordinator of PRMT5 and differentiation stimulator
    Monoclonal Antibody for Bovine Coordinator of PRMT5 and differentiation stimulator
    Protein for Bovine Coordinator of PRMT5 and differentiation stimulator
    Protein for Bovine Coordinator of PRMT5 and differentiation stimulator
    Protein for Bovine Coordinator of PRMT5 and differentiation stimulator

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2007-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Crossbred X Angus.
      tissue: Liver.
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