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Index > Protein center > MT-CO1(Gene name) > Bovine
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  • MT-CO1 (Gene name),
  • Cytochrome c oxidase subunit 1 (Protein name ),  COX1_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MT-CO1(COI;COXI;MTCO1);
    Protein name:
    Cytochrome c oxidase subunit 1;
    Alternative:
    Cytochrome c oxidase polypeptide I;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
    Subcellular Location:
    Mitochondrion inner membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    514
    Sequence:
    50:
    MFINRWLFST | NHKDIGTLYL | LFGAWAGMVG | TALSLLIRAE | LGQPGTLLGD | 
    100:
    DQIYNVVVTA | HAFVMIFFMV | MPIMIGGFGN | WLVPLMIGAP | DMAFPRMNNM | 
    150:
    SFWLLPPSFL | LLLASSMVEA | GAGTGWTVYP | PLAGNLAHAG | ASVDLTIFSL | 
    200:
    HLAGVSSILG | AINFITTIIN | MKPPAMSQYQ | TPLFVWSVMI | TAVLLLLSLP | 
    250:
    VLAAGITMLL | TDRNLNTTFF | DPAGGGDPIL | YQHLFWFFGH | PEVYILILPG | 
    300:
    FGMISHIVTY | YSGKKEPFGY | MGMVWAMMSI | GFLGFIVWAH | HMFTVGMDVD | 
    350:
    TRAYFTSATM | IIAIPTGVKV | FSWLATLHGG | NIKWSPAMMW | ALGFIFLFTV | 
    400:
    GGLTGIVLAN | SSLDIVLHDT | YYVVAHFHYV | LSMGAVFAIM | GGFVHWFPLF | 
    450:
    SGYTLNDTWA | KIHFAIMFVG | VNMTFFPQHF | LGLSGMPRRY | SDYPDAYTMW | 
    500:
    NTISSMGSFI | SLTAVMLMVF | IIWEAFASKR | EVLTVDLTTT | NLEWLNGCPP | 
    514:
    PYHTFEEPTY | VNLK
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Cytochrome c oxidase subunit 1
    Cat.:
    E8727h
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    96T
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    ELISA Kit for Bovine Cytochrome c oxidase subunit 1
    MSDS:
    Please sign in first.
    ELISA Kit for Bovine Cytochrome c oxidase subunit 1
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    Please sign in first.
    ELISA Kit for Bovine Cytochrome c oxidase subunit 1
    Cat.:
    E8727b
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    Packing:
    96T
    ELISA Kit for Bovine Cytochrome c oxidase subunit 1
    Cat.:
    E8727p
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    Packing:
    96T
    ELISA Kit for Bovine Cytochrome c oxidase subunit 1
    MSDS:
    Please sign in first.
    CLIA Kit for Bovine Cytochrome c oxidase subunit 1
    Cat.:
    U8727b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine Cytochrome c oxidase subunit 1
    MSDS:
    Please sign in first.
    CLIA Kit for Bovine Cytochrome c oxidase subunit 1
    MSDS:
    Please sign in first.
    CLIA Kit for Bovine Cytochrome c oxidase subunit 1
    MSDS:
    Please sign in first.
    CLIA Kit for Bovine Cytochrome c oxidase subunit 1
    Cat.:
    U8727h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine Cytochrome c oxidase subunit 1
    Cat.:
    U8727p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine Cytochrome c oxidase subunit 1
    Cat.:
    P8727Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Cytochrome c oxidase subunit 1
    Polyclonal Antibody for Bovine Cytochrome c oxidase subunit 1
    Polyclonal Antibody for Bovine Cytochrome c oxidase subunit 1
    Polyclonal Antibody for Bovine Cytochrome c oxidase subunit 1
    Polyclonal Antibody for Bovine Cytochrome c oxidase subunit 1
    Monoclonal Antibody for Bovine Cytochrome c oxidase subunit 1
    Monoclonal Antibody for Bovine Cytochrome c oxidase subunit 1
    Monoclonal Antibody for Bovine Cytochrome c oxidase subunit 1
    Monoclonal Antibody for Bovine Cytochrome c oxidase subunit 1
    Monoclonal Antibody for Bovine Cytochrome c oxidase subunit 1
    Monoclonal Antibody for Bovine Cytochrome c oxidase subunit 1
    Protein for Bovine Cytochrome c oxidase subunit 1
    Protein for Bovine Cytochrome c oxidase subunit 1
    Protein for Bovine Cytochrome c oxidase subunit 1
    Protein for Bovine Cytochrome c oxidase subunit 1
    Protein for Bovine Cytochrome c oxidase subunit 1
    Protein for Bovine Cytochrome c oxidase subunit 1

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    Recovery
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    Linearity
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    References
    1. 1.
      "Complete sequence of bovine mitochondrial DNA. Conserved features of the mammalian mitochondrial genome."
      Anderson S. , de Bruijn M.H.L. , Coulson A.R. , Eperon I.C. , Sanger F. , Young I.G.
      J. Mol. Biol.156:683-717(1982) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Heart.
    2. 2.
      "Studies on cytochrome-c oxidase, XIV. The amino-acid sequence of subunit I -- proteinchemical methods for the analysis of a large hydrophobic membrane protein."
      Hensel S. , Buse G.
      Biol. Chem. Hoppe-Seyler371:411-422(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE;FORMYLATION AT MET-1
      tissue: Heart.
    3. 3.
      "Bos taurus mitochondrial protein coding regions."
      Wettstein P.J.
      Submitted (2002-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: 65.
      strain: 66.
      strain: D.
      strain: F.
    4. 4.
      "Evidence for a copper-coordinated histidine-tyrosine cross-link in the active site of cytochrome oxidase."
      Buse G. , Soulimane T. , Dewor M. , Meyer H.E. , Blueggel M.
      Protein Sci.8:985-990(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: COVALENT BOND
    5. 5.
      "The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 A."
      Tsukihara T. , Aoyama H. , Yamashita E. , Tomizaki T. , Yamaguchi H. , Shinzawa-Itoh K. , Nakashima R. , Yaono R. , Yoshikawa S.
      Science272:1136-1144(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS)
    6. 6.
      "Structure analysis of bovine heart cytochrome c oxidase at 2.8 A resolution."
      Tomizaki T. , Yamashita E. , Yamaguchi H. , Aoyama H. , Tsukihara T. , Shinzawa-Itoh K. , Nakashima R. , Yaono R. , Yoshikawa S.
      Acta Crystallogr. D55:31-45(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS)
      tissue: Heart.
    7. 7.
      "X-ray structure of azide-bound fully oxidized cytochrome c oxidase from bovine heart at 2.9 A resolution."
      Fei M.J. , Yamashita E. , Inoue N. , Yao M. , Yamaguchi H. , Tsukihara T. , Shinzawa-Itoh K. , Nakashima R. , Yoshikawa S.
      Acta Crystallogr. D56:529-535(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS)
      tissue: Heart.
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