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Index > Protein center > Cep250(Gene name) > Mouse
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  • Cep250 (Gene name),
  • Centrosome-associated protein CEP250 (Protein name ),  CP250_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Cep250(Cep2;Inmp);
    Protein name:
    Centrosome-associated protein CEP250;
    Alternative:
    Centrosomal Nek2-associated protein 1(C-Nap1);250 kDa centrosomal protein(Cep250);Intranuclear matrix protein;Centrosomal protein 2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Monomer and homodimer (Probable). Forms a complex in vitro with both NEK2 kinase and the PPP1CC catalytic subunit of protein phosphatase 1 (PP1). Interacts with CEP135 (By similarity). Interacts with CROCC/rootletin.
    Function:
    Probably plays an important role in centrosome cohesion during interphase.
    Subcellular Location:
    Cytoplasm perinuclear region Cytoplasm cytoskeleton centrosome centriole Cytoplasm cytoskeleton cilium basal body Component of the core centrosome where it is found at the proximal ends of centrioles. In photoreceptors, found at the proximal ends of basal bodies.
    Protein Attributes:
    Sequence length:
    2414
    Sequence:
    50:
    METGSPGLNM | KPQSLQLVLE | GQVLALQQQM | AENQAASWRK | LKNSQEAQKR | 
    100:
    QATLVRKLQA | KVLQYRSWCQ | DLEKRLEATG | GLIPQRWESV | EEPNLEQLLI | 
    150:
    RLEEEQQRCE | SLVEVNTELR | LHMEKADVVN | KALQEDVEKL | TVDWSRARDE | 
    200:
    LVRKESQWRM | EQEFFKGYLR | GEHGRLLNLW | REVVTFRRHF | LKMKSATDRD | 
    250:
    LTELKAEHAR | LSGSLLTCCL | RLTLRAQSRE | SSGSGRTEES | EPARLLLLVA | 
    300:
    KTQALEKEAH | EKSQELMQLK | SHGDLEKAEL | QDRVTELSAL | LTQSQKQNED | 
    350:
    YEKMVKALRE | TMEILETNHA | ELMEHEASLS | RNAQEEKLSL | QQVIKAITQA | 
    400:
    LASVEEEDTV | TQSSGHEDSL | QSDCNGLSQF | DPQDPDRALT | LVQSVLTRRQ | 
    450:
    QAVQDLRQQL | SGCQEAMSFL | QQQHDQWEEE | GRALREKLQK | LTGERDALAG | 
    500:
    QTVGLQGEVD | SLSRERELLQ | KARGELQQQL | EVLEQEAWRL | RRMNMELQLQ | 
    550:
    GDSAQGEKLE | QQEELHLAVR | ERERLQETLV | GLEAKQSESL | SELLTLREAL | 
    600:
    ESSRLEGELL | KQERVEVAAA | LARAEQSIVE | LSGSENSLKA | EVADLRAAAV | 
    650:
    KLGALNEALA | LDKVELNQQL | LQLEQENQSL | CSRVEAAEQL | RSALQVDLAE | 
    700:
    AERRREALWE | KKTQLETQLQ | KAEEAGAELQ | AELRGTREEK | EELKDKLSEA | 
    750:
    HHQQETATAH | LEQLHQDAER | QEETLARAVQ | EKEALVRERA | ALEVRLQAVE | 
    800:
    RDRQDLTEHV | LGLRSAKEQL | ESNLFEAQQQ | NSVIQVTKGQ | LEVQIQTIIQ | 
    850:
    AKEVIQGEVK | CLKLELDAER | TRAEQEWDAV | ARQLAQAEQE | GQASLERQKV | 
    900:
    AHEEEVNRLQ | EKWEKERSWL | QQELDKTLET | LERERAELET | KLREQQTEME | 
    950:
    AIRAQREEER | SQADSALYQM | QLETEKERVS | LLETLLRTQK | ELADASQQLE | 
    1000:
    RLRQDMKIQK | LKEQETTGML | QAQLQETQQE | LKEAAQQHRD | DLAAFQKDKL | 
    1050:
    DLQKQVEDLM | SQLVAHDDSQ | RLVKEEIEEK | VKVAQECSRI | QKELEKENAS | 
    1100:
    LALSLVEKEK | RLLILQEADS | VRQQELSSLR | QDIQEAQEGQ | RELGVQVELL | 
    1150:
    RQEVKEKEAD | FVAREAQLLE | ELEASRVAEQ | QLRASLWAQE | AKATQLQLQL | 
    1200:
    RSTESQLEAL | VAEQQPENQA | QAQLASLCSV | LQQALGSACE | SRPELRGGGD | 
    1250:
    SAPTLWGPDP | DQNGASRLFK | RWSLPTALSP | EAVALALQKL | HQDVWKARQA | 
    1300:
    RDDLRDQVQK | LVQRLTDTEA | QKSQVHSELQ | DLQRQLSQSQ | EEKSKWEGRQ | 
    1350:
    NSLESELRDL | HETAASLQSR | LRQAELQKME | AQNDRELLQA | SKEKLSAQVE | 
    1400:
    HLQACVAEAQ | AQADAAAVLE | EDLRTARSAL | KLKNEELESE | RERAQALQEQ | 
    1450:
    GELKVAQGKA | LQENLALLAQ | TLSNREREVE | TLQAEVQELE | KQREMQKAAL | 
    1500:
    ELLSLDLKKR | SREVDLQQEQ | IQELEQCRSV | LEHLPMAVQE | REQKLSVQRD | 
    1550:
    QIRELENDRE | AQRSVLEHQL | LDLEQKAQVI | ESQRGQIQDL | KKQLGTLECL | 
    1600:
    ALELEESHHK | VESQQKMITE | LEGQREMQRV | ALTHLTLDLE | ERSQELQAQS | 
    1650:
    SQLHELENHS | THLAKELQER | DQEVTSQRQQ | IDELQKQQEQ | LAQALERKGQ | 
    1700:
    ELVLQKERIQ | VLEDQRTLQT | KILEEDLEQI | KHSLRERSQE | LASQWQLVHE | 
    1750:
    RADDGKSPSK | GQRGSLEHLK | LILRDKEKEV | ECQQERIQEL | QGHMGQLEQQ | 
    1800:
    LQGLHRKVGE | TSLLLTHREQ | ETATLQQHLQ | EAKEQGELRE | QVLQGQLEEA | 
    1850:
    QRDLAQRDHE | LETLRQEKQQ | TQDQEESMKL | KTSALQAALE | QAHATLKERQ | 
    1900:
    GELEEHREQV | RRLQEELEVE | GRQVRALEEV | LGDLRAESRE | HEKAVLALQQ | 
    1950:
    RCAEQAQEHE | AEARTLQDSW | LQAQATLTEQ | EQELAALRAE | NQYSRRQEEA | 
    2000:
    AVSQAEALQE | ALSKAQAALQ | EKEQSLLEQA | ELSHTLEAST | AALQATLDTC | 
    2050:
    QASARQLEEA | LRIREGEIQA | QALQHHEVTQ | HLQQELCQKK | EELRQLLEKA | 
    2100:
    GARRSQENGI | QEKQSLEQER | QEETRRLLES | LKELQLTVAQ | REEEILMLRE | 
    2150:
    ASSPRHRALP | AEKPALQPLP | AQQELERLQT | ALRQTEAREI | EWREKAQDLA | 
    2200:
    LSLAQSKASI | SSLQEITMFL | QASVLERESE | QQRLQEELVL | SRQALEEQQS | 
    2250:
    GGPHSTSRAD | QGPKVGQGSQ | SGEVETEPSP | GVEEKERLTQ | RLERLQQAVA | 
    2300:
    ELEVDRSKLQ | CHNAQLRTAL | EQVERERRKL | KRDSVRASRA | GSLEARETMT | 
    2350:
    SSPTQQDGRG | SQRGSSDSVL | VVELQREVAL | LRAQLALERK | QRQDYIARSV | 
    2400:
    QTSRELAGLH | HSLSHSLLTV | AQAPEATVLE | AETRKLDESL | NQSLTSPGPC | 
    2414:
    LLHPSLDTTQ | NTHR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Centrosome-associated protein CEP250
    ELISA Kit for Mouse Centrosome-associated protein CEP250
    CLIA Kit for Mouse Centrosome-associated protein CEP250
    CLIA Kit for Mouse Centrosome-associated protein CEP250
    Polyclonal Antibody for Mouse Centrosome-associated protein CEP250
    Polyclonal Antibody for Mouse Centrosome-associated protein CEP250
    Monoclonal Antibody for Mouse Centrosome-associated protein CEP250
    Monoclonal Antibody for Mouse Centrosome-associated protein CEP250
    Protein for Mouse Centrosome-associated protein CEP250
    Protein for Mouse Centrosome-associated protein CEP250

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Rootletin interacts with C-Nap1 and may function as a physical linker between the pair of centrioles/basal bodies in cells."
      Yang J. , Adamian M. , Li T.
      Mol. Biol. Cell17:1033-1040(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;INTERACTION WITH CROCC
      strain: C57BL/6 X 129/Sv.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-686 AND 1966-2414
      strain: C57BL/6J.
      tissue: Cerebellum.
      tissue: Corpora quadrigemina.
    4. 4.
      "INMP, a novel intranuclear matrix protein related to the family of intermediate filament-like proteins: molecular cloning and sequence analysis."
      Menz K. , Radomski N. , Jost E.
      Biochim. Biophys. Acta1309:14-20(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1806-2414
      tissue: Macrophage.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1872-2414
      strain: C57BL/6.
      tissue: Brain.
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