Protein name:
Cytochrome P450 26B1 ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Function:
Involved in the metabolism of retinoic acid (RA), rendering this classical morphogen inactive through oxidation. Involved in the specific inactivation of all-trans-retinoic acid (all-trans-RA), with a preference for the following substrates: all-trans-RA > 9-cis-RA > 13-cis-RA. Generates several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA, and 18-OH-RA. Esential for postnatal survival. Plays a central role in germ cell development: acts by degrading RA in the developing testis, preventing STRA8 expression, thereby leading to delay of meiosis. Required for the maintenance of the undifferentiated state of male germ cells during embryonic development in Sertoli cells, inducing arrest in G0 phase of the cell cycle and preventing meiotic entry. Plays a role in skeletal development, both at the level of patterning and in the ossification of bone and the establishment of some synovial joints.
Subcellular Location:
Endoplasmic reticulum membrane
Peripheral membrane protein
Microsome membrane
Peripheral membrane protein
Protein Attributes:
50:
MLFEGLELVS | ALATLAACLV | SVTLLLAVSQ | QLWQLRWAAT | RDKSCKLPIP |
100:
KGSMGFPLIG | ETGHWLLQGS | GFQSSRREKY | GNVFKTHLLG | RPLIRVTGAE |
150:
NVRKILMGEH | HLVSTEWPRS | TRMLLGPNTV | SNSIGDIHRN | KRKVFSKIFS |
200:
HEALESYLPK | IQLVIQDTLR | AWSSHPEAIN | VYQEAQKLTF | RMAIRVLLGF |
250:
SIPEEDLGHL | FEVYQQFVEN | VFSLPVDLPF | SGYRRGIQAR | QTLQKGLEKA |
300:
IREKLQCTQG | KDYSDALDIL | IESSKEHGKE | MTMQELKDGT | LELIFAAYAT |
350:
TASASTSLIM | QLLKHPAVLE | KLREELRAKG | LLHSGGCPCE | GTLRLDTLSG |
400:
LHYLDCVIKE | VMRLFTPVSG | GYRTVLQTFE | LDGFQIPKGW | SVMYSIRDTH |
450:
DTAPVFKDVN | VFDPDRFGQA | RSEDKDGRFH | YLPFGGGVRT | CLGKHLAKLF |
500:
LKVLAVELAS | TSRFELATRT | FPRITLVPVL | HPVDGLSVKF | FGLDSNQNKI |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Rat
Human
Mouse
ELISA Kit for Bovine Cytochrome P450 26B1
ELISA Kit for Bovine Cytochrome P450 26B1
ELISA Kit for Bovine Cytochrome P450 26B1
ELISA Kit for Bovine Cytochrome P450 26B1
CLIA Kit for Bovine Cytochrome P450 26B1
CLIA Kit for Bovine Cytochrome P450 26B1
CLIA Kit for Bovine Cytochrome P450 26B1
CLIA Kit for Bovine Cytochrome P450 26B1
Polyclonal Antibody for Bovine Cytochrome P450 26B1
Polyclonal Antibody for Bovine Cytochrome P450 26B1
Polyclonal Antibody for Bovine Cytochrome P450 26B1
Polyclonal Antibody for Bovine Cytochrome P450 26B1
Monoclonal Antibody for Bovine Cytochrome P450 26B1
Monoclonal Antibody for Bovine Cytochrome P450 26B1
Monoclonal Antibody for Bovine Cytochrome P450 26B1
Monoclonal Antibody for Bovine Cytochrome P450 26B1
Protein for Bovine Cytochrome P450 26B1
Protein for Bovine Cytochrome P450 26B1
Protein for Bovine Cytochrome P450 26B1
Protein for Bovine Cytochrome P450 26B1
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
"A whole-genome assembly of the domestic cow, Bos taurus."
Zimin A.V.
,
Delcher A.L.
,
Florea L.
,
Kelley D.R.
,
Schatz M.C.
,
Puiu D.
,
Hanrahan F.
,
Pertea G.
,
Van Tassell C.P.
,
Sonstegard T.S.
,
Marcais G.
,
Roberts M.
,
Subramanian P.
,
Yorke J.A.
,
Salzberg S.L.
Genome Biol.10:R42.01-R42.10(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
Hereford .