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Index > Protein center > Cyp51a1(Gene name) > Rat
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  • Cyp51a1 (Gene name),
  • Lanosterol 14-alpha demethylase (Protein name ),  CP51A_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Cyp51a1(Cyp51);
    Protein name:
    Lanosterol 14-alpha demethylase(LDM);
    Alternative:
    Cytochrome P450 51A1;CYPLI;Cytochrome P450LI;Cytochrome P450-14DM(Cytochrome P45014DM);Sterol 14-alpha demethylase;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
    Subcellular Location:
    Endoplasmic reticulum membrane Microsome membrane
    Protein Attributes:
    Sequence length:
    503
    Sequence:
    50:
    MVLLGLLQSG | GSVLGQAMEQ | VTGGNLLSTL | LIACAFTLSL | VYLFRLAVGH | 
    100:
    MVQLPAGAKS | PPYIYSPIPF | LGHAIAFGKS | PIEFLENAYE | KYGPVFSFTM | 
    150:
    VGKTFTYLLG | SDAAALLFNS | KNEDLNAEEV | YGRLTTPVFG | KGVAYDVPNA | 
    200:
    VFLEQKKILK | SGLNIAHFKQ | YVSIIEKEAK | EYFKSWGESG | ERNVFEALSE | 
    250:
    LIILTASHCL | HGKEIRSQLN | EKVAQLYADL | DGGFSHAAWL | LPGWLPLPSF | 
    300:
    RRRDRAHREI | KNIFYKAIQK | RRLSKEPAED | ILQTLLDSTY | KDGRPLTDDE | 
    350:
    IAGMLIGLLL | AGQHTSSTTS | AWMGFFLARD | KPLQDKCYLE | QKTVCGEDLP | 
    400:
    PLTYEQLKDL | NLLDRCIKET | LRLRPPIMTM | MRMAKTPQTV | AGYTIPPGHQ | 
    450:
    VCVSPTVNQR | LKDSWVERLD | FNPDRYLQDN | PASGEKFAYV | PFGAGRHRCI | 
    500:
    GENFAYVQIK | TIWSTMLRLY | EFDLINGYFP | SVNYTTMIHT | PENPVIRYKR | 
    503:
    RSK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat LDM
    ELISA Kit for Rat LDM
    ELISA Kit for Rat LDM
    ELISA Kit for Rat LDM
    ELISA Kit for Rat LDM
    CLIA Kit for Rat LDM
    CLIA Kit for Rat LDM
    CLIA Kit for Rat LDM
    CLIA Kit for Rat LDM
    CLIA Kit for Rat LDM
    Polyclonal Antibody for Rat LDM
    Polyclonal Antibody for Rat LDM
    Polyclonal Antibody for Rat LDM
    Polyclonal Antibody for Rat LDM
    Polyclonal Antibody for Rat LDM
    Monoclonal Antibody for Rat LDM
    Monoclonal Antibody for Rat LDM
    Monoclonal Antibody for Rat LDM
    Monoclonal Antibody for Rat LDM
    Monoclonal Antibody for Rat LDM
    Protein for Rat LDM
    Protein for Rat LDM
    Protein for Rat LDM
    Protein for Rat LDM
    Protein for Rat LDM

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    Precision
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    Linearity
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    References
    1. 1.
      "Occurrence of a P450 showing high homology to yeast lanosterol 14-demethylase (P450(14DM)) in the rat liver."
      Aoyama Y. , Funae Y. , Noshiro M. , Horiuchi T. , Yoshida Y.
      Biochem. Biophys. Res. Commun.201:1320-1326(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    2. 2.
      "Structural and evolutionary studies on sterol 14-demethylase P450 (CYP51), the most conserved P450 monooxygenase: I. Structural analyses of the gene and multiple sizes of mRNA."
      Noshiro M. , Aoyama Y. , Kawamoto T. , Gotoh O. , Horiuchi T. , Yoshida Y.
      J. Biochem.122:1114-1121(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
      strain: Wistar.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Kidney.
    4. 4.
      "Cloning and functional expression of the cDNA encoding rat lanosterol 14-alpha demethylase."
      Sloane D.L. , So O.Y. , Leung R. , Scarafia L.E. , Saldou N. , Jarnagin K. , Swinney D.C.
      Gene161:243-248(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 18-503
      tissue: Liver.
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