Gene name:
Creb3l2 (Ra69) ;
Protein name:
Cyclic AMP-responsive element-binding protein 3-like protein 2 (cAMP-responsive element-binding protein 3-like protein 2) ;
Alternative:
SCI-related protein Ra69 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Binds DNA as a dimer.
Function:
Transcriptional activator which is processed and activated during endoplasmic reticulum stress late phase. Binds to the cAMP response element (CRE) and activates transcription through CRE. Regulates the transcription of unfolded protein response target genes, preventing accumulation of unfolded proteins in damaged neurons. Also regulates the expression of SEC23A, accelerating protein trafficking from the ER to the Golgi thereby playing a key role in chondrocyte differentiation and formation of epiphyseal cartilage.
Subcellular Location:
Processed cyclic AMP-responsive element-binding protein 3-like protein 2
Nucleus
Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus.
Protein Attributes:
50:
MEVLESGEQS | VLQWDRKLSE | LSEPGETEAL | MYHTHFSELL | DEFSQNVLGQ |
100:
LLNDPFLSEK | SVSMEVEPSP | TSPAPLIQAE | HSYSLSEEPR | AQSPFTHVAA |
150:
SDGFNDEEVE | SEKWYLSTEF | PSATIKTEPI | TEEQPPGLVP | SVTLTITAIS |
200:
TPFEKEESPL | DMSAGGDSSC | QTLIPKIKLE | PHEVDQFLNF | SPKEASVDQL |
250:
HLPPTPPSSH | SSDSEGSLSP | NPRLHPFSLS | QAHSPGRAMP | RGPSALSTSP |
300:
LLTAPHKLQG | SGPLVLTEEE | KRTLIAEGYP | IPTKLPLTKS | EEKALKKIRR |
350:
KIKNKISAQE | SRRKKKEYMD | SLEKKVESCS | TENLELRKKV | EVLENTNRTL |
400:
LQQLQKLQTL | VMGKVSRTCK | LAGTQTGTCL | MVVVLCFAVA | FGSLFQGYGL |
450:
YPSATKMALP | SQHPLSEPYT | ASVVRSRNLL | IYEEHSSLEE | SSSPASAGEL |
500:
GGWDRGSSLL | RASSGLEALP | EVDLPHFIIS | KETSLEKSVL | LELQQHLVSS |
521:
KLEGNETLKV | VELERRVNAT | F
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Human
ELISA Kit for Rat cAMP-responsive element-binding protein 3-like protein 2
ELISA Kit for Rat cAMP-responsive element-binding protein 3-like protein 2
ELISA Kit for Rat cAMP-responsive element-binding protein 3-like protein 2
CLIA Kit for Rat cAMP-responsive element-binding protein 3-like protein 2
CLIA Kit for Rat cAMP-responsive element-binding protein 3-like protein 2
CLIA Kit for Rat cAMP-responsive element-binding protein 3-like protein 2
Polyclonal Antibody for Rat cAMP-responsive element-binding protein 3-like protein 2
Polyclonal Antibody for Rat cAMP-responsive element-binding protein 3-like protein 2
Polyclonal Antibody for Rat cAMP-responsive element-binding protein 3-like protein 2
Monoclonal Antibody for Rat cAMP-responsive element-binding protein 3-like protein 2
Monoclonal Antibody for Rat cAMP-responsive element-binding protein 3-like protein 2
Monoclonal Antibody for Rat cAMP-responsive element-binding protein 3-like protein 2
Protein for Rat cAMP-responsive element-binding protein 3-like protein 2
Protein for Rat cAMP-responsive element-binding protein 3-like protein 2
Protein for Rat cAMP-responsive element-binding protein 3-like protein 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Rattus norvegicus mRNA for SCI induced protein."
Liu S.
,
Ma Z.
Submitted (2004-02) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Wistar .