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Index > Protein center > Creb3l3(Gene name) > Mouse
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  • Creb3l3 (Gene name),
  • Cyclic AMP-responsive element-binding protein 3-like protein 3 (Protein name ),  CR3L3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Creb3l3(Crebh);
    Protein name:
    Cyclic AMP-responsive element-binding protein 3-like protein 3(cAMP-responsive element-binding protein 3-like protein 3);
    Alternative:
    Transcription factor CREB-H;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Binds DNA as a dimer. Probably homodimerizes. Probably forms a heterodimer with ATF6. Interacts with ATF6.
    Function:
    Transcription factor that may act during endoplasmic reticulum stress by activating unfolded protein response target genes. Activated in response to cAMP stimulation. Binds to the cAMP response element (CRE). Activates transcription through box-B element (By similarity). Activates transcription through CRE. Seems to function synergistically with ATF6. In acute inflammatory response, may activate expression of acute phase response (APR) genes. May be involved in growth suppression.
    Subcellular Location:
    Processed cyclic AMP-responsive element-binding protein 3-like protein 3 Nucleus Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus.
    Protein Attributes:
    Sequence length:
    479
    Sequence:
    50:
    MDGDIAAGKM | ASPVCAMAPL | DSMEVLDLLF | DRQDGILRNV | ELAEGWILAR | 
    100:
    EEQKVLLNSD | SDEFLNCILG | PGDSDPSSPL | WSPADSDSGI | SEDLPSDPQD | 
    150:
    TPPRSGTEPA | NTVARCHTRE | QGKGPCPSYL | PSTPCPEPPR | TQVQESSVAI | 
    200:
    DLDMWSTDTL | YPEEPAGSPS | RFNLTVKELL | LSGGSGDLQQ | HSLAASQLLG | 
    250:
    PGSGHCQELV | LTEDEKKLLA | KEGVTLPTQL | PLTKYEERVL | KKIRRKIRNK | 
    300:
    QSAQESRKKK | KEYIDGLENR | MSACTAQNQE | LQRKVLHLEK | QNLSLLEQLK | 
    350:
    HLQALVVQST | SKPAHAGTCI | AVLLLSFALI | ILPSISPFNS | NKVDSPGDFV | 
    400:
    PVRVFSRTLH | NHAASRVAPD | VTPGSEVPGP | WPDVGTPHKG | PSSGGLSADW | 
    450:
    GNFLEIPMLD | NLTEELDNST | LVLANSTEDL | GRATLLDWVA | SEPLLSPGRV | 
    479:
    GLEIPGEMWL | SWVPRWLRVR | LVQDALGVL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse cAMP-responsive element-binding protein 3-like protein 3
    ELISA Kit for Mouse cAMP-responsive element-binding protein 3-like protein 3
    ELISA Kit for Mouse cAMP-responsive element-binding protein 3-like protein 3
    ELISA Kit for Mouse cAMP-responsive element-binding protein 3-like protein 3
    CLIA Kit for Mouse cAMP-responsive element-binding protein 3-like protein 3
    CLIA Kit for Mouse cAMP-responsive element-binding protein 3-like protein 3
    CLIA Kit for Mouse cAMP-responsive element-binding protein 3-like protein 3
    CLIA Kit for Mouse cAMP-responsive element-binding protein 3-like protein 3
    Polyclonal Antibody for Mouse cAMP-responsive element-binding protein 3-like protein 3
    Polyclonal Antibody for Mouse cAMP-responsive element-binding protein 3-like protein 3
    Polyclonal Antibody for Mouse cAMP-responsive element-binding protein 3-like protein 3
    Polyclonal Antibody for Mouse cAMP-responsive element-binding protein 3-like protein 3
    Monoclonal Antibody for Mouse cAMP-responsive element-binding protein 3-like protein 3
    Monoclonal Antibody for Mouse cAMP-responsive element-binding protein 3-like protein 3
    Monoclonal Antibody for Mouse cAMP-responsive element-binding protein 3-like protein 3
    Monoclonal Antibody for Mouse cAMP-responsive element-binding protein 3-like protein 3
    Protein for Mouse cAMP-responsive element-binding protein 3-like protein 3
    Protein for Mouse cAMP-responsive element-binding protein 3-like protein 3
    Protein for Mouse cAMP-responsive element-binding protein 3-like protein 3
    Protein for Mouse cAMP-responsive element-binding protein 3-like protein 3

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    Linearity
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    References
    1. 1.
      "The liver-enriched transcription factor CREB-H is a growth suppressor protein underexpressed in hepatocellular carcinoma."
      Chin K.-T. , Zhou H.-J. , Wong C.-M. , Lee J.M.-F. , Chan C.-P. , Qiang B.-Q. , Yuan J.-G. , Ng I.-O. , Jin D.-Y.
      Nucleic Acids Res.33:1859-1873(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      strain: C57BL/10.
      tissue: Liver.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Ovary.
      tissue: Uterus.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Liver.
    4. 4.
      "Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response."
      Zhang K. , Shen X. , Wu J. , Sakaki K. , Saunders T. , Rutkowski D.T. , Back S.H. , Kaufman R.J.
      Cell124:587-599(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
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