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Index > Protein center > CREB3L4(Gene name) > Human
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  • CREB3L4 (Gene name),
  • Cyclic AMP-responsive element-binding protein 3-like protein 4 (Protein name ),  CR3L4_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CREB3L4(AIBZIP;CREB4;JAL);
    Protein name:
    Cyclic AMP-responsive element-binding protein 3-like protein 4(cAMP-responsive element-binding protein 3-like protein 4);
    Alternative:
    Attaching to CRE-like 1(ATCE1);Androgen-induced basic leucine zipper protein(AIbZIP);Transcript induced in spermiogenesis protein 40(Tisp40);Cyclic AMP-responsive element-binding protein 4(CREB-4;cAMP-responsive element-binding protein 4);hJAL;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Binds DNA as a dimer.
    Function:
    Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements.
    Subcellular Location:
    Processed cyclic AMP-responsive element-binding protein 3-like protein 4 Nucleus Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus.
    Protein Attributes:
    Sequence length:
    395
    Sequence:
    50:
    MDLGIPDLLD | AWLEPPEDIF | STGSVLELGL | HCPPPEVPVT | RLQEQGLQGW | 
    100:
    KSGGDRGCGL | QESEPEDFLK | LFIDPNEVYC | SEASPGSDSG | ISEDPCHPDS | 
    150:
    PPAPRATSSP | MLYEVVYEAG | ALERMQGETG | PNVGLISIQL | DQWSPAFMVP | 
    200:
    DSCMVSELPF | DAHAHILPRA | GTVAPVPCTT | LLPCQTLFLT | DEEKRLLGQE | 
    250:
    GVSLPSHLPL | TKAEERVLKK | VRRKIRNKQS | AQDSRRRKKE | YIDGLESRVA | 
    300:
    ACSAQNQELQ | KKVQELERHN | ISLVAQLRQL | QTLIAQTSNK | AAQTSTCVLI | 
    350:
    LLFSLALIIL | PSFSPFQSRP | EAGSEDYQPH | GVTSRNILTH | KDVTENLETQ | 
    395:
    VVESRLREPP | GAKDANGSTR | TLLEKMGGKP | RPSGRIRSVL | HADEM
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    String:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human cAMP-responsive element-binding protein 3-like protein 4
    ELISA Kit for Human cAMP-responsive element-binding protein 3-like protein 4
    ELISA Kit for Human cAMP-responsive element-binding protein 3-like protein 4
    CLIA Kit for Human cAMP-responsive element-binding protein 3-like protein 4
    CLIA Kit for Human cAMP-responsive element-binding protein 3-like protein 4
    CLIA Kit for Human cAMP-responsive element-binding protein 3-like protein 4
    Polyclonal Antibody for Human cAMP-responsive element-binding protein 3-like protein 4
    Polyclonal Antibody for Human cAMP-responsive element-binding protein 3-like protein 4
    Polyclonal Antibody for Human cAMP-responsive element-binding protein 3-like protein 4
    Monoclonal Antibody for Human cAMP-responsive element-binding protein 3-like protein 4
    Monoclonal Antibody for Human cAMP-responsive element-binding protein 3-like protein 4
    Monoclonal Antibody for Human cAMP-responsive element-binding protein 3-like protein 4
    Protein for Human cAMP-responsive element-binding protein 3-like protein 4
    Protein for Human cAMP-responsive element-binding protein 3-like protein 4
    Protein for Human cAMP-responsive element-binding protein 3-like protein 4

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "AIbZIP, a novel bZIP gene located on chromosome 1q21.3 that is highly expressed in prostate tumors and of which the expression is up-regulated by androgens in LNCaP human prostate cancer cells."
      Qi H. , Fillion C. , Labrie Y. , Grenier J. , Fournier A. , Berger L. , El-Alfy M. , Labrie C.
      Cancer Res.62:721-733(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
    2. 2.
      "Molecular cloning and characterization of a novel human cAMP response element-binding (CREB) gene (CREB4)."
      Cao G. , Ni X. , Jiang M. , Ma Y. , Cheng H. , Guo L. , Ji C. , Gu S. , Xie Y. , Mao Y.
      J. Hum. Genet.47:373-376(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
    3. 3.
      "Homo sapiens and Mus musculus JAL gene."
      Fujita K. , Hatakeyama S. , Ishikawa F.
      Submitted (2000-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1)
    4. 4.
      "Human ATCE1 - a novel protein that contains a CRE binding domain."
      Guo J.H. , Dai F.Y. , Yu L.
      Submitted (2001-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Uterus.
    6. 6.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Skin.
    9. 9.
      "Tisp40, a spermatid specific bZip transcription factor, functions by binding to the unfolded protein response element via the Rip pathway."
      Nagamori I. , Yabuta N. , Fujii T. , Tanaka H. , Yomogida K. , Nishimune Y. , Nojima H.
      Genes Cells10:575-594(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TOPOLOGY;GLYCOSYLATION
    10. 10.
      "CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P."
      Stirling J. , O'hare P.
      Mol. Biol. Cell17:413-426(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;MUTAGENESIS OF ARG-335
    11. 11.
      "Evaluation of AIbZIP and Cdc47 as markers for human prostatic diseases."
      Levesque M.H. , El-Alfy M. , Berger L. , Labrie F. , Labrie C.
      Urology69:196-201(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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