Creb3l4 ELISA Kit for Mouse(Mus musculus) | EIAab.comCreb3l4 ELISA Kit for Mouse(Mus musculus) | EIAab.com

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Creb3l4 (Gene name),

Cyclic AMP-responsive element-binding protein 3-like protein 4 (Protein name ), CR3L4_MOUSE from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Related Databases

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Gene name:

Creb3l4(Atce1;Jal;Tisp40);

Protein name:

Cyclic AMP-responsive element-binding protein 3-like protein 4(cAMP-responsive element-binding protein 3-like protein 4);

Alternative:

Transcript induced in spermiogenesis protein 40(Tisp40);Attaching to CRE-like 1(ATCE1;Acre1);mJAL;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Binds DNA as a dimer (By similarity). Forms a heterodimer with CREM isoform Tau.

Function:

Transcriptional activator that may play a role in the unfolded protein response of the testis. Proposed to be involved in spermiogenesis. May be involved in regulating the maturation of sperm head nuclei. Alternatively proposed to be a paternally delivered transcription factor that may function in early zygotic gene activation. Increases the binding of CREM isoform Tau with CRE. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE but not through UPRE and may recruit HIRA to CRE to regulate histone exchange.

Subcellular Location:

Processed cyclic AMP-responsive element-binding protein 3-like protein 4 Nucleus Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus.

Protein Attributes:

Sequence length:

370

Sequence:

50:

MELGCPELLE | PPEDIFSTGS | FLELGFNGPA | SKVPVTRGLQ | KSEPDDFLNL |

100:

FIDPNMIHCS | ETSPGRDSGV | SEDPGSPAQQ | ASSSPALYEV | VYDSGTLQGT |

150:

QREAGPTFGL | ISIQIDQWTP | ALMVPDACTV | SGLPSDSHRH | ILPRVSTRAP |

200:

APPAAMPSCQ | HHLFLTDEEK | QLLAQEGITL | PSHLPLTKAE | ERILKKIRRK |

250:

IRNKQSAQDS | RRRKKEYLDG | LESRVAACSE | QNQKLQRKVQ | ELERQNIFLM |

300:

EQVRQLQKLT | AQTSSRAAQT | STCVLILLFS | LALIILPSFS | PFQGQSEARP |

350:

EDYQLHGVIS | RNILTHENVT | ENLESPVLKS | KLEELPEAPT | TNGSTKTHLK |

370:

MRVKARPPGQ | IRGMVHTDEM |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

KEGG:

Pfam:

String:

STRING:

10090.ENSMUSP00000102992

SMR:

Uniprot:

FOR

ELISA Kit for Mouse cAMP-responsive element-binding protein 3-like protein 4

ELISA Kit for Mouse cAMP-responsive element-binding protein 3-like protein 4

ELISA Kit for Mouse cAMP-responsive element-binding protein 3-like protein 4

CLIA Kit for Mouse cAMP-responsive element-binding protein 3-like protein 4

CLIA Kit for Mouse cAMP-responsive element-binding protein 3-like protein 4

CLIA Kit for Mouse cAMP-responsive element-binding protein 3-like protein 4

Polyclonal Antibody for Mouse cAMP-responsive element-binding protein 3-like protein 4

Polyclonal Antibody for Mouse cAMP-responsive element-binding protein 3-like protein 4

Polyclonal Antibody for Mouse cAMP-responsive element-binding protein 3-like protein 4

Monoclonal Antibody for Mouse cAMP-responsive element-binding protein 3-like protein 4

Monoclonal Antibody for Mouse cAMP-responsive element-binding protein 3-like protein 4

Monoclonal Antibody for Mouse cAMP-responsive element-binding protein 3-like protein 4

Protein for Mouse cAMP-responsive element-binding protein 3-like protein 4

Protein for Mouse cAMP-responsive element-binding protein 3-like protein 4

Protein for Mouse cAMP-responsive element-binding protein 3-like protein 4

R&D Technical Data

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Precision

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Recovery

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Linearity

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References

1.

"Use of stepwise subtraction to comprehensively isolate mouse genes whose transcription is up-regulated during spermiogenesis."
Fujii T. , Tamura K. , Masai K. , Tanaka H. , Nishimune Y. , Nojima H.
EMBO Rep.3:367-372(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue: Testis.
2.

"Atce1: a novel mouse cyclic adenosine 3',5'-monophosphate-responsive element-binding protein-like gene exclusively expressed in postmeiotic spermatids."
Stelzer G. , Don J.
Endocrinology143:1578-1588(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY;DNA-BINDING
3.

"Tisp40, a spermatid specific bZip transcription factor, functions by binding to the unfolded protein response element via the Rip pathway."
Nagamori I. , Yabuta N. , Fujii T. , Tanaka H. , Yomogida K. , Nishimune Y. , Nojima H.
Genes Cells10:575-594(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);PROTEOLYTIC PROCESSING;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;MUTAGENESIS OF LEU-283 AND ARG-311
tissue: Testis.
4.

"Homo sapiens and Mus musculus JAL gene."
Fujita K. , Hatakeyama S. , Ishikawa F.
Submitted (2000-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
5.

"Mouse Acre1 contains CRE binding domain."
Guo J.H. , Dai F.Y. , Yu L.
Submitted (2001-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
6.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain: C57BL/6J.
strain: NOD.
tissue: Pituitary.
tissue: Testis.
tissue: Thymus.
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain: FVB/N.
tissue: Salivary gland.
8.

"Reduction of spermatogenesis but not fertility in Creb3l4-deficient mice."
Adham I.M. , Eck T.J. , Mierau K. , Muller N. , Sallam M.A. , Paprotta I. , Schubert S. , Hoyer-Fender S. , Engel W.
Mol. Cell. Biol.25:7657-7664(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
9.

"The enigma of ATCE1, an acrosome-associated transcription factor."
Gil S. , Yosef D. , Golan N. , Don J.
Dev. Biol.298:201-211(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
10.

"The testes-specific bZip type transcription factor Tisp40 plays a role in ER stress responses and chromatin packaging during spermiogenesis."
Nagamori I. , Yomogida K. , Ikawa M. , Okabe M. , Yabuta N. , Nojima H.
Genes Cells11:1161-1171(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
11.

"Stage-specific expression of the Atce1/Tisp40alpha isoform of CREB3L4 in mouse spermatids."
El-Alfy M. , Azzi L. , Lessard J. , Lavergne E. , Pelletier M. , Labrie C.
J. Androl.27:686-694(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
12.

"Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation."
Nagamori I. , Yomogida K. , Adams P.D. , Sassone-Corsi P. , Nojima H.
J. Biol. Chem.281:15073-15081(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CREM

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