Gene name:
Creb3l4 (Aibzip) ;
Protein name:
Cyclic AMP-responsive element-binding protein 3-like protein 4 (cAMP-responsive element-binding protein 3-like protein 4) ;
Alternative:
Androgen-induced basic leucine zipper protein (AIbZIP) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Binds DNA as a dimer. Forms a heterodimer with CREM isoform Delta.
Function:
Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements. Increases the binding of CREM isoform Delta with CRE. The CREM isoform Delta-CREB3L4 heterodimer functions through CRE but not through UPRE and may recruit HIRA to CRE to regulate histone exchange.
Subcellular Location:
Processed cyclic AMP-responsive element-binding protein 3-like protein 4
Nucleus
Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus.
Protein Attributes:
50:
MELGCPELLE | PPEDIFSTGS | FLELGFNGPP | SKVPGLQKSE | SDDFLNLFID |
100:
PNMIRCSETS | PGSDSGVSED | PGSPAPQAPS | SPALYEVVYE | AGALQGTQRE |
150:
AGPTFGLISI | QIDQWSPAFM | VPGACTVSDL | PSEAHRHILP | RVSTIAPPPP |
200:
AALLSCQRLF | LTDEEKHLLG | QEGVTLPSHL | PLTKAEERIL | KKIRRKIRNK |
250:
QSAQDSRRRK | KEYIDGLESR | VAACSEQNQK | LQRKVQELER | QNISLVAQVH |
300:
QLQKFTAQTS | SRAAQTSTCV | LILLFSLALI | ILPSFSPFQS | QPEARSEGYQ |
350:
LHGVISRNIL | THEDMTESPE | SPVLKANLEE | LPQVPATNGS | TKMAHLKMRV |
367:
KARPTGPIRG | MVHADEM
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Rat cAMP-responsive element-binding protein 3-like protein 4
ELISA Kit for Rat cAMP-responsive element-binding protein 3-like protein 4
ELISA Kit for Rat cAMP-responsive element-binding protein 3-like protein 4
CLIA Kit for Rat cAMP-responsive element-binding protein 3-like protein 4
CLIA Kit for Rat cAMP-responsive element-binding protein 3-like protein 4
CLIA Kit for Rat cAMP-responsive element-binding protein 3-like protein 4
Polyclonal Antibody for Rat cAMP-responsive element-binding protein 3-like protein 4
Polyclonal Antibody for Rat cAMP-responsive element-binding protein 3-like protein 4
Polyclonal Antibody for Rat cAMP-responsive element-binding protein 3-like protein 4
Monoclonal Antibody for Rat cAMP-responsive element-binding protein 3-like protein 4
Monoclonal Antibody for Rat cAMP-responsive element-binding protein 3-like protein 4
Monoclonal Antibody for Rat cAMP-responsive element-binding protein 3-like protein 4
Protein for Rat cAMP-responsive element-binding protein 3-like protein 4
Protein for Rat cAMP-responsive element-binding protein 3-like protein 4
Protein for Rat cAMP-responsive element-binding protein 3-like protein 4
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
strain :
Sprague-Dawley .
tissue :
Prostate .