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Index > Protein center > CRADD(Gene name) > Human
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  • CRADD (Gene name),
  • Death domain-containing protein CRADD (Protein name ),  CRADD_HUMAN from NCBI database.
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  • General Annotation
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  • Gene name:
    CRADD(RAIDD);
    Protein name:
    Death domain-containing protein CRADD;
    Alternative:
    RIP-associated protein with a death domain;Caspase and RIP adapter with death domain;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with LRDD.
    Function:
    Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    199
    Sequence:
    50:
    MEARDKQVLR | SLRLELGAEV | LVEGLVLQYL | YQEGILTENH | IQEINAQTTG | 
    100:
    LRKTMLLLDI | LPSRGPKAFD | TFLDSLQEFP | WVREKLKKAR | EEAMTDLPAG | 
    150:
    DRLTGIPSHI | LNSSPSDRQI | NQLAQRLGPE | WEPMVLSLGL | SQTDIYRCKA | 
    199:
    NHPHNVQSQV | VEAFIRWRQR | FGKQATFQSL | HNGLRAVEVD | PSLLLHMLE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    KEGG:
    Pfam:
    SMR:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Death domain-containing protein CRADD
    ELISA Kit for Human Death domain-containing protein CRADD
    CLIA Kit for Human Death domain-containing protein CRADD
    CLIA Kit for Human Death domain-containing protein CRADD
    Polyclonal Antibody for Human Death domain-containing protein CRADD
    Polyclonal Antibody for Human Death domain-containing protein CRADD
    Monoclonal Antibody for Human Death domain-containing protein CRADD
    Monoclonal Antibody for Human Death domain-containing protein CRADD
    Protein for Human Death domain-containing protein CRADD
    Protein for Human Death domain-containing protein CRADD

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP."
      Ahmad M. , Srinivasula S.M. , Wang L. , Talanian R.V. , Litwack G. , Fernandes-Alnemri T. , Alnemri E.S.
      Cancer Res.57:615-619(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "RAIDD is a new 'death' adaptor molecule."
      Duan H. , Dixit V.M.
      Nature385:86-89(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Brain.
    4. 4.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Colon.
    6. 6.
      "The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress."
      Tinel A. , Tschopp J.
      Science304:843-846(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PIDD
    7. 7.
      "Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage."
      Vakifahmetoglu H. , Olsson M. , Orrenius S. , Zhivotovsky B.
      Oncogene25:5683-5692(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PIDD
    8. 8.
      "Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment."
      Chou J.J. , Matsuo H. , Duan H. , Wagner G.
      Cell94:171-180(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1-100
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MRT34 ARG-128
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