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Index > Protein center > Orai1(Gene name) > Mouse
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  • Orai1 (Gene name),
  • Calcium release-activated calcium channel protein 1 (Protein name ),  CRCM1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Orai1(Cracm1;Tmem142a);
    Protein name:
    Calcium release-activated calcium channel protein 1;
    Alternative:
    Transmembrane protein 142A;Protein orai-1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with STIM1 and STIM2. Interacts with EFCAB4B/CRACR2A; the interaction is direct and takes place in absence of Ca(2+). Forms a complex with EFCAB4B/CRACR2A and STIM1 at low concentration of Ca(2+), the complex dissociates at elevated Ca(2+) concentrations.
    Function:
    Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    304
    Sequence:
    50:
    MHPEPAPPPS | HSNPELPVSG | GSSTSGSRRS | RRRSGDGEPS | GAPPLPPPPP | 
    100:
    AVSYPDWIGQ | SYSEVMSLNE | HSMQALSWRK | LYLSRAKLKA | SSRTSALLSG | 
    150:
    FAMVAMVEVQ | LDTDHDYPPG | LLIVFSACTT | VLVAVHLFAL | MISTCILPNI | 
    200:
    EAVSNVHNLN | SVKESPHERM | HRHIELAWAF | STVIGTLLFL | AEVVLLCWVK | 
    250:
    FLPLKRQAGQ | PSPTKPPAES | VIVANHSDSS | GITPGEAAAI | ASTAIMVPCG | 
    300:
    LVFIVFAVHF | YRSLVSHKTD | RQFQELNELA | EFARLQDQLD | HRGDHSLTPG | 
    304:
    THYA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Calcium release-activated calcium channel protein 1
    Cat.:
    E15347r
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    96T
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    ELISA Kit for Mouse Calcium release-activated calcium channel protein 1
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    E15347h
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    96T
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    ELISA Kit for Mouse Calcium release-activated calcium channel protein 1
    Cat.:
    E15347m
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    96T
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    ELISA Kit for Mouse Calcium release-activated calcium channel protein 1
    Cat.:
    E15347c
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    Packing:
    96T
    CLIA Kit for Mouse Calcium release-activated calcium channel protein 1
    Cat.:
    U15347h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Calcium release-activated calcium channel protein 1
    Cat.:
    U15347r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Calcium release-activated calcium channel protein 1
    Cat.:
    U15347m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Calcium release-activated calcium channel protein 1
    Cat.:
    U15347c
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Calcium release-activated calcium channel protein 1
    Polyclonal Antibody for Mouse Calcium release-activated calcium channel protein 1
    Cat.:
    P15347Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Calcium release-activated calcium channel protein 1
    Cat.:
    P15347Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Calcium release-activated calcium channel protein 1
    Cat.:
    P15347Rb-h
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Calcium release-activated calcium channel protein 1
    Monoclonal Antibody for Mouse Calcium release-activated calcium channel protein 1
    Monoclonal Antibody for Mouse Calcium release-activated calcium channel protein 1
    Monoclonal Antibody for Mouse Calcium release-activated calcium channel protein 1
    Protein for Mouse Calcium release-activated calcium channel protein 1
    Protein for Mouse Calcium release-activated calcium channel protein 1
    Protein for Mouse Calcium release-activated calcium channel protein 1
    Protein for Mouse Calcium release-activated calcium channel protein 1

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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Mammary gland.
      tissue: Stomach.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 16-304
      strain: Czech II.
      tissue: Mammary gland.
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