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Index > Protein center > CRK(Gene name) > Chicken
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  • CRK (Gene name),
  • Adapter molecule crk (Protein name ),  CRK_CHICK from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CRK;
    Protein name:
    Adapter molecule crk;
    Alternative:
    p38;Proto-oncogene c-Crk;
    Organism:
    Chicken (Gallus gallus). 
    General Annotation
    Sub Unit:
    Interacts with ABL1, C3G, SOS, MAP4K1, MAPK8 and DOCK1 via its first SH3 domain. Interacts with BCAR1, CBL, PXN and GAB1 via its SH2 domain upon stimulus-induced tyrosine phosphorylation. Interacts with several tyrosine-phosphorylated growth factor receptors such as EGFR, PDGFR and INSR via its SH2 domain.
    Function:
    May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling.
    Subcellular Location:
    Cytoplasm Cell membrane Translocated to the plasma membrane upon cell adhesion.
    Protein Attributes:
    Sequence length:
    305
    Sequence:
    50:
    MAGQFDSEDR | GSWYWGRLSR | GDAVSLLQGQ | RHGTFLVRDS | GSIPGDFVLS | 
    100:
    VSESSRVSHY | IVNSLGPAGG | RRAGGEGPGA | PGLNPTRFRI | GDQEFDSLPS | 
    150:
    LLEFYKIHYL | DTTTLIEPVS | RSRQNSGVIL | RQEEVEYVRA | LFDFNGNDDE | 
    200:
    DLPFKKGDIL | KIRDKPEEQW | WNAEDMDGKR | GMIPVPYVEK | CRPSSASVST | 
    250:
    LTGGNQDSSH | PQPLGGPEPG | PYAQPSINTP | LPNLQNGPFY | ARVIQKRVPN | 
    300:
    AYDKTALALE | VGELVKVTKI | NMSGQWEGEC | NGKRGHFPFT | HVRLLDQQNP | 
    305:
    DEDFS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Chicken Adapter molecule crk
    Cat.:
    E9658m
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Chicken Adapter molecule crk
    Cat.:
    E9658h
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    Packing:
    96T
    ELISA Kit for Chicken Adapter molecule crk
    Cat.:
    E9658r
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    Packing:
    96T
    ELISA Kit for Chicken Adapter molecule crk
    Cat.:
    E9658c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Chicken Adapter molecule crk
    Cat.:
    U9658c
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    Packing:
    96T
    CLIA Kit for Chicken Adapter molecule crk
    Cat.:
    U9658r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Chicken Adapter molecule crk
    Cat.:
    U9658h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Adapter molecule crk
    Cat.:
    U9658m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Chicken Adapter molecule crk
    Cat.:
    P9658Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken Adapter molecule crk
    Cat.:
    P9658Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken Adapter molecule crk
    Polyclonal Antibody for Chicken Adapter molecule crk
    Cat.:
    P9658Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Chicken Adapter molecule crk
    Monoclonal Antibody for Chicken Adapter molecule crk
    Monoclonal Antibody for Chicken Adapter molecule crk
    Monoclonal Antibody for Chicken Adapter molecule crk
    Protein for Chicken Adapter molecule crk
    Protein for Chicken Adapter molecule crk
    Protein for Chicken Adapter molecule crk
    Protein for Chicken Adapter molecule crk

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    Precision
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    References
    1. 1.
      "The product of the cellular crk gene consists primarily of SH2 and SH3 regions."
      Reichman C.T. , Mayer B.J. , Khawer S. , Hanafusa H.
      Cell Growth Differ.3:451-460(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Structural basis for regulation of the Crk signaling protein by a proline switch."
      Sarkar P. , Saleh T. , Tzeng S.R. , Birge R.B. , Kalodimos C.G.
      Nat. Chem. Biol.7:51-57(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 135-297;ISOMERIZATION AT PRO-238
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