Protein name:
Adapter molecule crk ;
Alternative:
p38 ;Proto-oncogene c-Crk ;
Organism:
Chicken (Gallus gallus).
General Annotation
Sub Unit:
Interacts with ABL1, C3G, SOS, MAP4K1, MAPK8 and DOCK1 via its first SH3 domain. Interacts with BCAR1, CBL, PXN and GAB1 via its SH2 domain upon stimulus-induced tyrosine phosphorylation. Interacts with several tyrosine-phosphorylated growth factor receptors such as EGFR, PDGFR and INSR via its SH2 domain.
Function:
May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling.
Subcellular Location:
Cytoplasm
Cell membrane
Translocated to the plasma membrane upon cell adhesion.
Protein Attributes:
50:
MAGQFDSEDR | GSWYWGRLSR | GDAVSLLQGQ | RHGTFLVRDS | GSIPGDFVLS |
100:
VSESSRVSHY | IVNSLGPAGG | RRAGGEGPGA | PGLNPTRFRI | GDQEFDSLPS |
150:
LLEFYKIHYL | DTTTLIEPVS | RSRQNSGVIL | RQEEVEYVRA | LFDFNGNDDE |
200:
DLPFKKGDIL | KIRDKPEEQW | WNAEDMDGKR | GMIPVPYVEK | CRPSSASVST |
250:
LTGGNQDSSH | PQPLGGPEPG | PYAQPSINTP | LPNLQNGPFY | ARVIQKRVPN |
300:
AYDKTALALE | VGELVKVTKI | NMSGQWEGEC | NGKRGHFPFT | HVRLLDQQNP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
Chicken
ELISA Kit for Chicken Adapter molecule crk
ELISA Kit for Chicken Adapter molecule crk
ELISA Kit for Chicken Adapter molecule crk
ELISA Kit for Chicken Adapter molecule crk
CLIA Kit for Chicken Adapter molecule crk
CLIA Kit for Chicken Adapter molecule crk
CLIA Kit for Chicken Adapter molecule crk
CLIA Kit for Chicken Adapter molecule crk
Polyclonal Antibody for Chicken Adapter molecule crk
Polyclonal Antibody for Chicken Adapter molecule crk
Polyclonal Antibody for Chicken Adapter molecule crk
Polyclonal Antibody for Chicken Adapter molecule crk
Monoclonal Antibody for Chicken Adapter molecule crk
Monoclonal Antibody for Chicken Adapter molecule crk
Monoclonal Antibody for Chicken Adapter molecule crk
Monoclonal Antibody for Chicken Adapter molecule crk
Protein for Chicken Adapter molecule crk
Protein for Chicken Adapter molecule crk
Protein for Chicken Adapter molecule crk
Protein for Chicken Adapter molecule crk
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 135-297;ISOMERIZATION AT PRO-238