Gene name:
CSNK2A3(CSNK2A1P);
Protein name:
Casein kinase II subunit alpha 3(CK II alpha 3);
Alternative:
Casein kinase II alpha 1 polypeptide pseudogene;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Heterotetramer composed of two catalytic subunits (alpha chain and/or alpha' chain) and two regulatory subunits (beta chains) (By similarity). Interacts with PML.
Function:
Probable catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Amplification-dependent oncogene; promotes cell proliferation and tumorigenesis by down-regulating expression of the tumor suppressor protein, PML. May play a role in the pathogenesis of the lung cancer development and progression.
Subcellular Location:
N/A
Protein Attributes:
50:
MSGPVPSRAR | VYTDVNTHRP | REYWDYESHV | VEWGNQDDYQ | LVRKLGRGKY |
100:
SEVFEAINIT | NNEKVVVKIL | KPVKKKKIKR | EIKILENLRG | GPNIITLADI |
150:
VKDPVSRTPA | LVFEHVNNTD | FKQLYQTLTD | YDIRFYMYEI | LKALDYCHSM |
200:
GIMHRDVKPH | NVMIDHEHRK | LRLIDWGLAE | FYHPGQEYNV | RVASRYFKGP |
250:
ELLVDYQMYD | YSLDMWRLGC | MLASMIFRKE | PFFHGRDNYD | QLVRIAKFLG |
300:
TEDLYGYIDK | YNIELDPRFN | DILGRHSRKR | WERFVHSENQ | HLVSPEALDF |
350:
LDKLLRYDHQ | SRLTAREAME | HPYFYTVVKD | QARMGSSSMP | GGSTPVSSAN |
391:
VMSGISSVPT | PSPLGPLAGS | PVIAAANPLG | MPVPAATGAQ | Q
Vaild Sequence:
Related Databases
Uniprot:
