COPS6 ELISA Kit for Pig(Sus scrofa) | EIAab.comCOPS6 ELISA Kit for Pig(Sus scrofa)

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COPS6 (Gene name),

COP9 signalosome complex subunit 6 (Protein name ), CSN6_PIG from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

COPS6;

Protein name:

COP9 signalosome complex subunit 6(SGN6;Signalosome subunit 6);

Alternative:

Organism:

Pig (Sus scrofa).

General Annotation

Sub Unit:

Component of the CSN complex, composed of COPS1/GPS1, COPS2, COPS3, COPS4, COPS5, COP6, COPS7 (COPS7A or COPS7B) and COPS8. In the complex, it probably interacts directly with COPS2, COPS4, COPS5 and COPS7 (COPS7A or COPS7B). Interacts with the translation initiation factor EIF3S6. Interacts weakly with RBX1.

Function:

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity.

Subcellular Location:

Cytoplasm Nucleus

Protein Attributes:

Sequence length:

323

Sequence:

50:

100:

150:

200:

250:

300:

323:

FVNKFNVLYD | RQGIGRRMRG | LFF

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Ssc.8359

KEGG:

ssc:100125954

Pfam:

PF01398

Uniprot:

A7TX81

FOR

ELISA Kit for Pig SGN6

CLIA Kit for Pig SGN6

Polyclonal Antibody for Pig SGN6

Monoclonal Antibody for Pig SGN6

Protein for Pig SGN6

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Chromosomal assignments of the porcine COPS2, COPS4, COPS5, COPS6, USP6 and USP10 genes involved in the ubiquitin-proteasome system."
Wu X. , Li K. , Yerle M. , Pan Y.C.
Anim. Genet.38:665-666(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Muscle.

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