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Index > Protein center > Csrp3(Gene name) > Mouse
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  • Csrp3 (Gene name),
  • Cysteine and glycine-rich protein 3 (Protein name ),  CSRP3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Csrp3(Clp;Mlp);
    Protein name:
    Cysteine and glycine-rich protein 3;
    Alternative:
    LIM domain protein, cardiac;Cysteine-rich protein 3(CRP3);Muscle LIM protein;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with LDHD (By similarity). Interacts with GLRX3.
    Function:
    Positive regulator of myogenesis. Plays a crucial and specific role in the organization of cytosolic structures in cardiomyocytes. Could play a role in mechanical stretch sensing. May be a scaffold protein that promotes the assembly of interacting proteins at Z-line structures. It is essential for calcineurin anchorage to the Z line. Required for stress-induced calcineurin-NFAT activation.
    Subcellular Location:
    Nucleus Cytoplasm Cytoplasm cytoskeleton Cytoplasm myofibril sarcomere Z line Mainly cytoplasmic. In the nucleus it associates with the actin cytoskeleton (Potential). In the Z line, found associated with GLRX3.
    Protein Attributes:
    Sequence length:
    194
    Sequence:
    50:
    MPNWGGGAKC | GACEKTVYHA | EEIQCNGRSF | HKTCFHCMAC | RKALDSTTVA | 
    100:
    AHESEIYCKV | CYGRRYGPKG | IGFGQGAGCL | STDTGEHLGL | QFQQSPKPAR | 
    150:
    AATTSNPSKF | SAKFGESEKC | PRCGKSVYAA | EKVMGGGKPW | HKTCFRCAIC | 
    194:
    GKSLESTNVT | DKDGELYCKV | CYAKNFGPTG | IGFGGLTQQV | EKKE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    SMR:
    KEGG:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Cysteine and glycine-rich protein 3
    Cat.:
    E15404h
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    96T
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    ELISA Kit for Mouse Cysteine and glycine-rich protein 3
    Cat.:
    E15404m
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    96T
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    ELISA Kit for Mouse Cysteine and glycine-rich protein 3
    Cat.:
    E15404r
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    96T
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    ELISA Kit for Mouse Cysteine and glycine-rich protein 3
    Cat.:
    E15404b
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    Packing:
    96T
    CLIA Kit for Mouse Cysteine and glycine-rich protein 3
    Cat.:
    U15404r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cysteine and glycine-rich protein 3
    Cat.:
    U15404m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cysteine and glycine-rich protein 3
    Cat.:
    U15404h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cysteine and glycine-rich protein 3
    Cat.:
    U15404b
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Cysteine and glycine-rich protein 3
    Cat.:
    P15404Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cysteine and glycine-rich protein 3
    Cat.:
    P15404Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cysteine and glycine-rich protein 3
    Polyclonal Antibody for Mouse Cysteine and glycine-rich protein 3
    Cat.:
    P15404Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Cysteine and glycine-rich protein 3
    Monoclonal Antibody for Mouse Cysteine and glycine-rich protein 3
    Monoclonal Antibody for Mouse Cysteine and glycine-rich protein 3
    Monoclonal Antibody for Mouse Cysteine and glycine-rich protein 3
    Protein for Mouse Cysteine and glycine-rich protein 3
    Protein for Mouse Cysteine and glycine-rich protein 3
    Protein for Mouse Cysteine and glycine-rich protein 3
    Protein for Mouse Cysteine and glycine-rich protein 3

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    References
    1. 1.
      "Murine MLP: cloning and expression in the embryonic head."
      Harrod G.V. , Kettunen P.J. , Jowett A.K.
      J. Craniofac. Genet. Dev. Biol.16:65-73(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: MF1.
      tissue: Mandible.
    2. 2.
      Hashimoto N. , Ogashiwa M.
      Submitted (1996-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C3H.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Liver.
    4. 4.
      "MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure."
      Arber S. , Hunter J.J. , Ross J. Jr. , Hongo M. , Sansig G. , Borg J. , Perriard J.C. , Chien K.R. , Caroni P.
      Cell88:393-403(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
      strain: 129/Sv.
    5. 5.
      "Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc."
      Heineke J. , Ruetten H. , Willenbockel C. , Gross S.C. , Naguib M. , Schaefer A. , Kempf T. , Hilfiker-Kleiner D. , Caroni P. , Kraft T. , Kaiser R.A. , Molkentin J.D. , Drexler H. , Wollert K.C.
      Proc. Natl. Acad. Sci. U.S.A.102:1655-1660(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
    6. 6.
      "PICOT attenuates cardiac hypertrophy by disrupting calcineurin-NFAT signaling."
      Jeong D. , Kim J.M. , Cha H. , Oh J.G. , Park J. , Yun S.H. , Ju E.S. , Jeon E.S. , Hajjar R.J. , Park W.J.
      Circ. Res.102:711-719(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GLRX3;SUBCELLULAR LOCATION
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF TRP-4
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