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Index > Protein center > Ctnna2(Gene name) > Mouse
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  • Ctnna2 (Gene name),
  • Catenin alpha-2 (Protein name ),  CTNA2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Ctnna2(Catna2);
    Protein name:
    Catenin alpha-2;
    Alternative:
    Alpha N-catenin;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with ZNF639.
    Function:
    May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation.
    Subcellular Location:
    Cytoplasm Cytoplasm cytoskeleton Cell junction adherens junction Cell membrane Peripheral membrane protein Cytoplasmic side Cell projection axon
    Protein Attributes:
    Sequence length:
    953
    Sequence:
    50:
    MTSATSPIIL | KWDPKSLEIR | TLTVERLLEP | LVTQVTTLVN | TSNKGPSGKK | 
    100:
    KGRSKKAHVL | AASVEQATQN | FLEKGEQIAK | ESQDLKEELV | AAVEDVRKQG | 
    150:
    ETMRIASSEF | ADDPCSSVKR | GTMVRAARAL | LSAVTRLLIL | ADMADVMRLL | 
    200:
    SHLKIVEEAL | EAVKNATNEQ | DLANRFKEFG | KEMVKLNYVA | ARRQQELKDP | 
    250:
    HCRDEMAAAR | GALKKNATML | YTASQAFLRH | PDVAATRANR | DYVFKQVQEA | 
    300:
    IAGISSAAQA | TSPTDEAKGH | TGIGELAAAL | NEFDNKIILD | PMTFSEARFR | 
    350:
    PSLEERLESI | ISGAALMADS | SCTRDDRRER | IVAECNAVRQ | ALQDLLSEYM | 
    400:
    NNTGRKEKGD | PLNIAIDKMT | KKTRDLRRQL | RKAVMDHISD | SFLETNVPLL | 
    450:
    VLIEAAKSGN | EKEVKEYAQV | FREHANKLVE | VANLACSISN | NEEGVKLVRM | 
    500:
    AATQIDSLCP | QVINAALTLA | ARPQSKVAQD | NMDVFKDQWE | KQVRVLTEAV | 
    550:
    DDITSVDDFL | SVSENHILED | VNKCVIALQE | GDVDTLDRTA | GAIRGRAARV | 
    600:
    IHIINAEMEN | YEAGVYTEKV | LEATKLLSET | VMPRFAEQVE | VAIEALSANV | 
    650:
    PQPFEENEFI | DASRLVYDGV | RDIRKAVLMI | RTPEELEDDS | DFEQEDYDVR | 
    700:
    SRTSVQTEDD | QLIAGQSARA | IMAQLPQEEK | AKIAEQVEIF | HQEKSKLDAE | 
    750:
    VAKWDDSGND | IIVLAKQMCM | IMMEMTDFTR | GKGPLKNTSD | VINAAKKIAE | 
    800:
    AGSRMDKLAR | AVADQCPDSA | CKQDLLAYLQ | RIALYCHQLN | ICSKVKAEVQ | 
    850:
    NLGGELIVSG | TGVQSTFTTF | YEVDCDVIDG | GRASQLSTHL | PTCAEGAPIG | 
    900:
    SGSSDSSMLD | SATSLIQAAK | NLMNAVVLTV | KASYVASTKY | QKVYGTAAVN | 
    950:
    SPVVSWKMKA | PEKKPLVKRE | KPEEFQTRVR | RGSQKKHISP | VQALSEFKAM | 
    953:
    DSF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    KEGG:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Catenin alpha-2
    ELISA Kit for Mouse Catenin alpha-2
    ELISA Kit for Mouse Catenin alpha-2
    CLIA Kit for Mouse Catenin alpha-2
    CLIA Kit for Mouse Catenin alpha-2
    CLIA Kit for Mouse Catenin alpha-2
    Polyclonal Antibody for Mouse Catenin alpha-2
    Polyclonal Antibody for Mouse Catenin alpha-2
    Polyclonal Antibody for Mouse Catenin alpha-2
    Monoclonal Antibody for Mouse Catenin alpha-2
    Monoclonal Antibody for Mouse Catenin alpha-2
    Monoclonal Antibody for Mouse Catenin alpha-2
    Protein for Mouse Catenin alpha-2
    Protein for Mouse Catenin alpha-2
    Protein for Mouse Catenin alpha-2

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    Linearity
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    References
    1. 1.
      "Mouse alpha N-catenin: two isoforms, specific expression in the nervous system, and chromosomal localization of the gene."
      Uchida N. , Shimamura K. , Miyatani S. , Copeland N.G. , Gilbert D.J. , Jenkins N.A. , Takeichi M.
      Dev. Biol.163:75-85(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      strain: C57BL/6J.
      tissue: Visual cortex.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: C57BL/6.
      tissue: Brain.
    4. 4.
      "Deletion in Catna2, encoding alpha N-catenin, causes cerebellar and hippocampal lamination defects and impaired startle modulation."
      Park C. , Falls W. , Finger J.H. , Longo-Guess C.M. , Ackerman S.L.
      Nat. Genet.31:279-284(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION;DEVELOPMENTAL STAGE
    5. 5.
      "Cadherin regulates dendritic spine morphogenesis."
      Togashi H. , Abe K. , Mizoguchi A. , Takaoka K. , Chisaka O. , Takeichi M.
      Neuron35:77-89(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
    6. 6.
      "Phosphoproteomic analysis of the developing mouse brain."
      Ballif B.A. , Villen J. , Beausoleil S.A. , Schwartz D. , Gygi S.P.
      Mol. Cell. Proteomics3:1093-1101(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-640 AND SER-901;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic brain.
    7. 7.
      "Stability of dendritic spines and synaptic contacts is controlled by alpha N-catenin."
      Abe K. , Chisaka O. , Van Roy F. , Takeichi M.
      Nat. Neurosci.7:357-363(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
    8. 8.
      "Switching of alpha-catenin from alphaE-catenin in the cortical ventricular zone to alphaN-catenin II in the intermediate zone."
      Ajioka I. , Nakajima K.
      Brain Res. Dev. Brain Res.160:106-111(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
    9. 9.
      "Differential expression of alpha-E-catenin and alpha-N-catenin in the developing cerebral cortex."
      Stocker A.M. , Chenn A.
      Brain Res.1073:151-158(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE;SUBCELLULAR LOCATION
    10. 10.
      "Alpha N-catenin deficiency causes defects in axon migration and nuclear organization in restricted regions of the mouse brain."
      Uemura M. , Takeichi M.
      Dev. Dyn.235:2559-2566(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;SUBCELLULAR LOCATION
    11. 11.
      "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
      Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
      Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-640;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
    12. 12.
      "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations."
      Munton R.P. , Tweedie-Cullen R. , Livingstone-Zatchej M. , Weinandy F. , Waidelich M. , Longo D. , Gehrig P. , Potthast F. , Rutishauser D. , Gerrits B. , Panse C. , Schlapbach R. , Mansuy I.M.
      Mol. Cell. Proteomics6:283-293(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain cortex.
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