Gene name:
Ctnnd1 (Catns;Kiaa0384) ;
Protein name:
Catenin delta-1 ;
Alternative:
p120 catenin (p120(ctn)) ;Cadherin-associated Src substrate (CAS) ;p120(cas) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Belongs to a multiprotein cell-cell adhesion complex that also contains E-cadherin, alpha-catenin, beta-catenin, and gamma-catenin. Binds to the C-terminal fragment of PSEN1 and mutually competes for E-cadherin (By similarity). Interacts with ZBTB33. Interacts with GLIS2 and FER. Interacts with NANOS1 (via N-terminal region).
Function:
May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors (By similarity). Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway. Promotes GLIS2 C-terminal cleavage.
Subcellular Location:
Cytoplasm
Nucleus
Cell membrane
Interaction with GLIS2 promotes nuclear translocation. NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
Protein Attributes:
50:
MDDSEVESTA | SILASVKEQE | AQFEKLTRAL | EEERRHVSAQ | LERVRVSPQD |
100:
ANSLMANGTL | TRRHQNGRFV | GDADLERQKF | SDLKLNGPQD | HNHLLYSTIP |
150:
RMQEPGQIVE | TYTEEDPEGA | MSVVSVETTD | DGTTRRTETT | VKKVVKTMTT |
200:
RTVQPVPMGP | DGLPVDASAV | SNNYIQTLGR | DFRKNGNGGP | GPYVGQAGTA |
250:
TLPRNFHYPP | DGYGRHYEDG | YPGGSDNYGS | LSRVTRIEER | YRPSMEGYRA |
300:
PSRQDVYGPQ | PQVRVGGSSV | DLHRFHPEPY | GLEDDQRSMG | YDDLDYGMMS |
350:
DYGTARRTGT | PSDPRRRLRS | YEDMIGEEVP | PDQYYWAPLA | QHERGSLASL |
400:
DSLRKGMPPP | SNWRQPELPE | VIAMLGFRLD | AVKSNAAAYL | QHLCYRNDKV |
450:
KTDVRKLKGI | PILVGLLDHP | KKEVHLGACG | ALKNISFGRD | QDNKIAIKNC |
500:
DGVPALVRLL | RKARDMDLTE | VITGTLWNLS | SHDSIKMEIV | DHALHALTDE |
550:
VIIPHSGWER | EPNEDCKPRH | IEWESVLTNT | AGCLRNVSSE | RSEARRKLRE |
600:
CDGLVDALIF | IVQAEIGQKD | SDSKLVENCV | CLLRNLSYQV | HREIPQAERY |
650:
QEALPTVANS | TGPHAASCFG | AKKGKDEWFS | RGKKPTEDPA | NDTVDFPKRT |
700:
SPARGYELLF | QPEVVRIYIS | LLKESKTPAI | LEASAGAIQN | LCAGRWTYGR |
750:
YIRSALRQEK | ALSAIAELLT | SEHERVVKAA | SGALRNLAVD | ARNKELIGKH |
800:
AIPNLVKNLP | GGQQNSSWNF | SEDTVVSILN | TINEVIAENL | EAAKKLRETQ |
850:
GIEKLVLINK | SGNRSEKEVR | AAALVLQTIW | GYKELRKPLE | KEGWKKSDFQ |
900:
VNLNNASRSQ | SSHSYDDSTL | PLIDRNQKSD | KKPDREEIPM | SNMGSNTKSL |
938:
DNNYSTLNER | GDHNRTLDRS | GDLGDMEPLK | GAPLMQKI
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Mouse Catenin delta-1
ELISA Kit for Mouse Catenin delta-1
CLIA Kit for Mouse Catenin delta-1
CLIA Kit for Mouse Catenin delta-1
Polyclonal Antibody for Mouse Catenin delta-1
Polyclonal Antibody for Mouse Catenin delta-1
Monoclonal Antibody for Mouse Catenin delta-1
Monoclonal Antibody for Mouse Catenin delta-1
Protein for Mouse Catenin delta-1
Protein for Mouse Catenin delta-1
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
strain :
Swiss .
2.
Reynolds A.B.
Submitted (1992-12) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
tissue :
Brain .
4.
"The transcriptional landscape of the mammalian genome."
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Science309:1559-1563(2005)
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[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
strain :
C57BL/6J .
tissue :
Testis .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
C57BL/6 .
tissue :
Brain .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH ZBTB33
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH ZBTB33
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;NUCLEAR LOCALIZATION SIGNAL;SUBCELLULAR LOCATION;MUTAGENESIS OF 622-LYS-LYS-623
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ERRATUM
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-217; TYR-221 AND TYR-280;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-904;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Mast cell .
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH GLIS2;FUNCTION;SUBCELLULAR LOCATION
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-230; SER-252; SER-288; SER-349; SER-847; SER-857; TYR-865 AND SER-899;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-349;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-228; TYR-257; SER-349; SER-352 AND TYR-904;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic fibroblast .