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Index > Protein center > CTNNAL1(Gene name) > Human
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  • CTNNAL1 (Gene name),
  • Alpha-catulin (Protein name ),  CTNL1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CTNNAL1;
    Protein name:
    Alpha-catulin;
    Alternative:
    Catenin alpha-like protein 1;Alpha-catenin-related protein(ACRP);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with ARHGEF1.
    Function:
    May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).
    Subcellular Location:
    Cytoplasm cytoskeleton Cell membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    734
    Sequence:
    50:
    MAASPGPAGV | GGAGAVYGSG | SSGFALDSGL | EIKTRSVEQT | LLPLVSQITT | 
    100:
    LINHKDNTKK | SDKTLQAIQR | VGQAVNLAVG | RFVKVGEAIA | NENWDLKEEI | 
    150:
    NIACIEAKQA | GETIAALTDI | TNLNHLESDG | QITIFTDKTG | VIKAARLLLS | 
    200:
    SVTKVLLLAD | RVVIKQIITS | RNKVLATMER | LEKVNSFQEF | VQIFSQFGNE | 
    250:
    MVEFAHLSGD | RQNDLKDEKK | KAKMAAARAV | LEKCTMMLLT | ASKTCLRHPN | 
    300:
    CESAHKNKEG | VFDRMKVALD | KVIEIVTDCK | PNGETDISSI | SIFTGIKEFK | 
    350:
    MNIEALRENL | YFQSKENLSV | TLEVILERME | DFTDSAYTSH | EHRERILELS | 
    400:
    TQARMELQQL | ISVWIQAQSK | KTKSIAEELE | LSILKISHSL | NELKKELHST | 
    450:
    ATQLAADLLK | YHADHVVLKA | LKLTGVEGNL | EALAEYACKL | SEQKEQLVET | 
    500:
    CRLLRHISGT | EPLEITCIHA | EETFQVTGQQ | IISAAETLTL | HPSSKIAKEN | 
    550:
    LDVFCEAWES | QISDMSTLLR | EINDVFEGRR | GEKYGYLSLP | KPMKNNANLK | 
    600:
    SLKPDKPDSE | EQAKIAKLGL | KLGLLTSDAD | CEIEKWEDQE | NEIVQYGRNM | 
    650:
    SSMAYSLYLF | TRGEGPLKTS | QDLIHQLEVF | AAEGLKLTSS | VQAFSKQLKD | 
    700:
    DDKLMLLLEI | NKLIPLCHQL | QTVTKTSLQN | KVFLKVDKCI | TKTRSMMALL | 
    734:
    VQLLSLCYKL | LKKLQMENNG | WVSVTNKDTM | DSKT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    SMR:
    KEGG:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Alpha-catulin
    ELISA Kit for Human Alpha-catulin
    CLIA Kit for Human Alpha-catulin
    CLIA Kit for Human Alpha-catulin
    Polyclonal Antibody for Human Alpha-catulin
    Polyclonal Antibody for Human Alpha-catulin
    Monoclonal Antibody for Human Alpha-catulin
    Monoclonal Antibody for Human Alpha-catulin
    Protein for Human Alpha-catulin
    Protein for Human Alpha-catulin

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Identification and chromosomal localization of CTNNAL1, a novel protein homologous to alpha-catenin."
      Zhang J.-S. , Nelson M. , Wang L. , Liu W. , Qian C.-P. , Shridhar V. , Urrutia R. , Smith D.I.
      Genomics54:149-154(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;INDUCTION
      tissue: Pancreatic cancer.
    2. 2.
      "Human alpha-catulin, a novel alpha-catenin-like molecule with conserved genomic structure, but deviating alternative splicing."
      Janssens B. , Staes K. , van Roy F.M.
      Biochim. Biophys. Acta1447:341-347(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1 AND 2);TISSUE SPECIFICITY
    3. 3.
      Kishi M. , Nagafuchi A. , Tsukita S.
      Submitted (1997-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    4. 4.
      "Isolation of a novel alpha-catenin-like gene from the familial dysautonomia candidate region on 9q31."
      Slaugenhaupt S.A. , Liebert C.B. , Leyne M. , Mull J. , Gill S. , Chadwick B.P. , Maayan C. , Axelrod F.B. , Blumenfeld A. , Gusella J.F.
      Submitted (1998-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    5. 5.
      Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
      Submitted (2005-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Gastric mucosa.
    6. 6.
      NIEHS SNPs program
      Submitted (2004-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS THR-91; LYS-203; GLN-527; ASN-593 AND ARG-716
    7. 7.
      "Human protein factory for converting the transcriptome into an in vitro-expressed proteome."
      Goshima N. , Kawamura Y. , Fukumoto A. , Miura A. , Honma R. , Satoh R. , Wakamatsu A. , Yamamoto J. , Kimura K. , Nishikawa T. , Andoh T. , Iida Y. , Ishikawa K. , Ito E. , Kagawa N. , Kaminaga C. , Kanehori K. , Kawakami B. , more...
      Nat. Methods5:1011-1017(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    8. 8.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    10. 10.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 296-734 (ISOFORM 3)
      tissue: Brain.
    12. 12.
      "Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation."
      Park B. , Nguyen N.T. , Dutt P. , Merdek K.D. , Bashar M. , Sterpetti P. , Tosolini A. , Testa J.R. , Toksoz D.
      J. Biol. Chem.277:45361-45370(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;SUBCELLULAR LOCATION;INTERACTION WITH ARHGEF1
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-538;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
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