Protein name:
Cation channel sperm-associated protein 4 (CatSper4) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Heterotetramer; possibly composed of CATSPER1, CATSPER2, CATSPER3 and CATSPER4 (Potential). Interacts with CATSPER1.
Function:
Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Activated by intracellular alkalinization. Contrary to the human ortholog, not activated by progesterone.
Subcellular Location:
Cell projection
cilium
flagellum membrane
Multi-pass membrane protein
Specifically located in the principal piece of sperm tail.
Protein Attributes:
50:
MSEKHKWWQQ | VENIDITHLG | PKRKAYELLG | RHEEQVLINR | RDVMEKKDAW |
100:
DVQEFITQMY | IKQLLRHPAF | QLLLAFLLLS | NAITIALRTN | SYLGQKHYEL |
150:
FSTIDDIVLT | ILICEVLLGW | LNGFWIFWKD | GWNILNFAIV | FILFMGFFIK |
200:
QLDMVAITYP | LRVLRLVHVC | MAVEPLARII | KVILQSMPDL | ANVMALILFF |
250:
MLVFSVFGVT | LFGAFVPKHF | QNMGVALYTL | FICITQDGWL | DIYTDFQMDE |
300:
REYAMEVGGA | IYFAVFITLG | AFIGLNLFVV | VVTTNLEQMM | KTGEEEGHLN |
350:
IKFTETEEDE | DWTDELPLVH | CTEARKDTST | VPKEPLVGGP | LSNLTEKTCD |
400:
NFCLVLEAIQ | ENLMEYKEIR | EELNMIVEEV | SSIRFNQEQQ | NVILHKYTSK |
442:
SATFLSEPPE | GANKQDLITA | LVSREKVSDS | NINMVNKHKF | SH
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse CatSper4
ELISA Kit for Mouse CatSper4
CLIA Kit for Mouse CatSper4
CLIA Kit for Mouse CatSper4
Polyclonal Antibody for Mouse CatSper4
Polyclonal Antibody for Mouse CatSper4
Monoclonal Antibody for Mouse CatSper4
Monoclonal Antibody for Mouse CatSper4
Protein for Mouse CatSper4
Protein for Mouse CatSper4
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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References
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Testis .
2.
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more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;TISSUE SPECIFICITY
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DEVELOPMENTAL STAGE
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;DISRUPTION PHENOTYPE
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INTERACTION WITH CATSPER1;DISRUPTION PHENOTYPE
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : LACK OF ACTIVATION BY PROGESTERONE AND PGE1
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION IN THE CATSPER COMPLEX
strain :
C57BL/6 .