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Index > Protein center > Gja10(Gene name) > Mouse
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  • Gja10 (Gene name),
  • Gap junction alpha-10 protein (Protein name ),  CXA10_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Gja10;
    Protein name:
    Gap junction alpha-10 protein;
    Alternative:
    Connexin-57(Cx57);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    A connexon is composed of a hexamer of connexins.
    Function:
    One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Involved in tracer coupling between horizontal cells of the retina. May play a role in the regulation of horizontal cell patterning.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein Cell junction gap junction
    Protein Attributes:
    Sequence length:
    505
    Sequence:
    50:
    MGDWNLLGGI | LEEVHSHSTI | VGKIWLTILF | IFRMLVLGVA | AEDVWDDEQS | 
    100:
    AFACNTQQPG | CNNICYDDAF | PISLIRFWVL | QIIFVSSPSL | VYMGHALYRL | 
    150:
    RDFEKQRQKK | KLYLRAQMEN | PELDLEEQQR | VDKELRRLEE | QKRIHKVPLK | 
    200:
    GCLLRTYVLH | ILTRSVLEVG | FMIGQYILYG | FQMHPIYKCT | QAPCPNSVDC | 
    250:
    FVSRPTEKTI | FMLFMHSIAA | ISLLLNILEI | FHLGIRKIMR | ALDGKSSSGN | 
    300:
    TENETGPPFH | STNYSGTQQC | MICSSLPERI | SLLQANNKQQ | VIRVNIPRSK | 
    350:
    SMWQIPHPRQ | LEVDVSCGKR | DWAEKIESCA | QLHVHSPCPH | DRSARIQHPG | 
    400:
    QQPCHSVFGP | KNAMSQSWFG | TMTASQHRPS | SALETWERSQ | GPEASGRSLT | 
    450:
    DRQSHFQGSD | GSARESGVWT | DRLGPGSRKA | SFLSRLMSEK | GQRHSDSGSS | 
    500:
    RSLNSSCLDF | SHGENSPSPL | PSATGHRASM | VSKSSHVDSP | PHSSFIIHET | 
    505:
    YVYVY
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Gap junction alpha-10 protein
    ELISA Kit for Mouse Gap junction alpha-10 protein
    CLIA Kit for Mouse Gap junction alpha-10 protein
    CLIA Kit for Mouse Gap junction alpha-10 protein
    Polyclonal Antibody for Mouse Gap junction alpha-10 protein
    Polyclonal Antibody for Mouse Gap junction alpha-10 protein
    Monoclonal Antibody for Mouse Gap junction alpha-10 protein
    Monoclonal Antibody for Mouse Gap junction alpha-10 protein
    Protein for Mouse Gap junction alpha-10 protein
    Protein for Mouse Gap junction alpha-10 protein

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Molecular cloning and functional expression of the mouse gap junction gene connexin-57 in human HeLa cells."
      Manthey D. , Bukauskas F. , Kozak C. , Willecke K. , Lee C.G.
      J. Biol. Chem.274:14716-14723(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "Functional expression of connexin57 in horizontal cells of the mouse retina."
      Hombach S. , Janssen-Bienhold U. , Soehl G. , Schubert T. , Buessow H. , Ott T. , Weiler R. , Willecke K.
      Eur. J. Neurosci.19:2633-2640(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 478-505 (ISOFORM 2);FUNCTION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;DISRUPTION PHENOTYPE
    4. 4.
      "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues."
      Soehl G. , Nielsen P.A. , Eiberger J. , Willecke K.
      Cell Commun. Adhes.10:27-36(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    5. 5.
      "Horizontal cell receptive fields are reduced in connexin57-deficient mice."
      Shelley J. , Dedek K. , Schubert T. , Feigenspan A. , Schultz K. , Hombach S. , Willecke K. , Weiler R.
      Eur. J. Neurosci.23:3176-3186(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
    6. 6.
      "Spatial relationships of connexin36, connexin57 and zonula occludens-1 in the outer plexiform layer of mouse retina."
      Ciolofan C. , Lynn B.D. , Wellershaus K. , Willecke K. , Nagy J.I.
      Neuroscience148:473-488(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    7. 7.
      "Ganglion cell adaptability: does the coupling of horizontal cells play a role?"
      Dedek K. , Pandarinath C. , Alam N.M. , Wellershaus K. , Schubert T. , Willecke K. , Prusky G.T. , Weiler R. , Nirenberg S.
      PLoS ONE3:E1714-E1714(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
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