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Index > Protein center > GJA4(Gene name) > Human
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  • GJA4 (Gene name),
  • Gap junction alpha-4 protein (Protein name ),  CXA4_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GJA4;
    Protein name:
    Gap junction alpha-4 protein;
    Alternative:
    Connexin-37(Cx37);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    A connexon is composed of a hexamer of connexins.
    Function:
    One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein Cell junction gap junction
    Protein Attributes:
    Sequence length:
    333
    Sequence:
    50:
    MGDWGFLEKL | LDQVQEHSTV | VGKIWLTVLF | IFRILILGLA | GESVWGDEQS | 
    100:
    DFECNTAQPG | CTNVCYDQAF | PISHIRYWVL | QFLFVSTPTL | VYLGHVIYLS | 
    150:
    RREERLRQKE | GELRALPAKD | PQVERALAAV | ERQMAKISVA | EDGRLRIRGA | 
    200:
    LMGTYVASVL | CKSVLEAGFL | YGQWRLYGWT | MEPVFVCQRA | PCPYLVDCFV | 
    250:
    SRPTEKTIFI | IFMLVVGLIS | LVLNLLELVH | LLCRCLSRGM | RARQGQDAPP | 
    300:
    TQGTSSDPYT | DQVFFYLPVG | QGPSSPPCPT | YNGLSSSEQN | WANLTTEERL | 
    333:
    ASSRPPLFLD | PPPQNGQKPP | SRPSSSASKK | QYV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    SMR:
    Pfam:
    MIM:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Gap junction alpha-4 protein
    ELISA Kit for Human Gap junction alpha-4 protein
    ELISA Kit for Human Gap junction alpha-4 protein
    ELISA Kit for Human Gap junction alpha-4 protein
    ELISA Kit for Human Gap junction alpha-4 protein
    CLIA Kit for Human Gap junction alpha-4 protein
    CLIA Kit for Human Gap junction alpha-4 protein
    CLIA Kit for Human Gap junction alpha-4 protein
    CLIA Kit for Human Gap junction alpha-4 protein
    CLIA Kit for Human Gap junction alpha-4 protein
    Polyclonal Antibody for Human Gap junction alpha-4 protein
    Polyclonal Antibody for Human Gap junction alpha-4 protein
    Polyclonal Antibody for Human Gap junction alpha-4 protein
    Polyclonal Antibody for Human Gap junction alpha-4 protein
    Polyclonal Antibody for Human Gap junction alpha-4 protein
    Monoclonal Antibody for Human Gap junction alpha-4 protein
    Monoclonal Antibody for Human Gap junction alpha-4 protein
    Monoclonal Antibody for Human Gap junction alpha-4 protein
    Monoclonal Antibody for Human Gap junction alpha-4 protein
    Monoclonal Antibody for Human Gap junction alpha-4 protein
    Protein for Human Gap junction alpha-4 protein
    Protein for Human Gap junction alpha-4 protein
    Protein for Human Gap junction alpha-4 protein
    Protein for Human Gap junction alpha-4 protein
    Protein for Human Gap junction alpha-4 protein

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning and functional expression of human connexin37, an endothelial cell gap junction protein."
      Reed K.E. , Westphale E.M. , Larson D.M. , Wang H.-Z. , Veenstra R.D. , Beyer E.C.
      J. Clin. Invest.91:997-1004(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      Beyer E.C.
      Submitted (1999-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    3. 3.
      "A connexin 37 genotypic variant in atherosclerosis."
      van Zeijl L. , Cotgreave I.A.
      Submitted (1999-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS SER-71; VAL-128; ILE-130 AND SER-319
    4. 4.
      "Functional expression and biophysical properties of two polymorphic forms of human connexin37."
      Kumari S. , Varadaraj K. , Valiunas V. , Ramanan S.V. , Beyer E.C. , Brink P.R.
      Submitted (1999-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS ILE-130 AND SER-319
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Placenta.
    6. 6.
      "Connexin 37 mutation screening in anovulatory polycystic ovary syndrome."
      Lench N.J. , Williams G. , Williams E. , Gharani N. , Franks S.
      Submitted (1999-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    7. 7.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Ovary.
      tissue: Pancreas.
      tissue: Spleen.
    10. 10.
      "Human connexin 37 is polymorphic but not mutated in tumours."
      Krutovskikh V. , Mironov N. , Yamasaki H.
      Carcinogenesis17:1761-1763(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ILE-130
    11. 11.
      "A genetic polymorphism in connexin 37 as a prognostic marker for atherosclerotic plaque development."
      Boerma M. , Forsberg L. , Van Zeijl L. , Morgenstern R. , De Faire U. , Lemne C. , Erlinge D. , Thulin T. , Hong Y. , Cotgreave I.A.
      J. Intern. Med.246:211-218(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SER-319
    12. 12.
      "Human hemangiosarcomas have a common polymorphism but no mutations in the connexin37 gene."
      Saito T. , Krutovskikh V. , Marion M.J. , Ishak K.G. , Bennett W.P. , Yamasaki H.
      Int. J. Cancer86:67-70(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SER-319
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