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Index > Protein center > CXCL11(Gene name) > Human
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  • CXCL11 (Gene name),
  • C-X-C motif chemokine 11 (Protein name ),  CXL11_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CXCL11(ITAC;SCYB11;SCYB9B);
    Protein name:
    C-X-C motif chemokine 11;
    Alternative:
    H174;Beta-R1;Interferon-inducible T-cell alpha chemoattractant(I-TAC);Interferon gamma-inducible protein 9(IP-9);Small-inducible cytokine B11;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    94
    Sequence:
    50:
    MSVKGMAIAL | AVILCATVVQ | GFPMFKRGRC | LCIGPGVKAV | KVADIEKASI | 
    94:
    MYPSNNCDKI | EVIITLKENK | GQRCLNPKSK | QARLIIKKVE | RKNF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    SMR:
    UniGene:
    Pfam:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human C-X-C motif chemokine 11
    Cat.:
    E1081h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human C-X-C motif chemokine 11
    Cat.:
    E1081m
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human C-X-C motif chemokine 11
    Cat.:
    E1081b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human C-X-C motif chemokine 11
    Cat.:
    U1081m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human C-X-C motif chemokine 11
    Cat.:
    U1081h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human C-X-C motif chemokine 11
    Cat.:
    U1081b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human C-X-C motif chemokine 11
    Cat.:
    P1081Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human C-X-C motif chemokine 11
    Polyclonal Antibody for Human C-X-C motif chemokine 11
    Cat.:
    P1081Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human C-X-C motif chemokine 11
    Monoclonal Antibody for Human C-X-C motif chemokine 11
    Monoclonal Antibody for Human C-X-C motif chemokine 11
    Protein for Human C-X-C motif chemokine 11
    Protein for Human C-X-C motif chemokine 11
    Protein for Human C-X-C motif chemokine 11

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Characterization of beta-R1, a gene that is selectively induced by interferon beta (IFN-beta) compared with IFN-alpha."
      Rani M.R.S. , Foster G.R. , Leung S. , Leaman D. , Stark G.R. , Ransohoff R.M.
      J. Biol. Chem.271:22878-22884(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Astrocyte.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Peripheral blood monocyte.
    3. 3.
      "Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3."
      Cole K.E. , Strick C.A. , Paradis T.J. , Ogborne K.T. , Loetscher M. , Gladue R.P. , Lin W. , Boyd J.G. , Moser B. , Wood D.E. , Sahagan B.G. , Neote K.
      J. Exp. Med.187:2009-2021(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Fetal astrocyte.
    4. 4.
      "Human IP-9: a keratinocyte derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3)."
      Tensen C.P. , Flier J. , van der Raaij-Helmer E.M.H. , Sampat-Sardjoepersad S. , van der Schors R.C. , Leurs R. , Scheper R.J. , Boorsma D.M. , Willemze R.
      J. Invest. Dermatol.112:716-722(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 22-38;MASS SPECTROMETRY
      tissue: Keratinocyte.
    5. 5.
      "Structure and expression of the human small cytokine B subfamily member 11 (SCYB11/formerly SCYB9B, alias I-TAC) gene cloned from IFN-gamma-treated human monocytes (THP-1)."
      Laich A.M. , Meyer M. , Werner E.R. , Werner-Felmayer G.
      J. Interferon Cytokine Res.19:505-513(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
      tissue: Myeloma.
    6. 6.
      "Genomic organization, sequence and transcriptional regulation of the human CXCL 11 gene."
      Tensen C.P. , Flier J. , Rampersad S. , Sampat-Sardjoepersad S. , Scheper R.J. , Boorsma D.M. , Willemze R.
      Biochim. Biophys. Acta1446:167-172(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Keratinocyte.
    7. 7.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Bone marrow.
      tissue: Brain.
      tissue: Liver.
    9. 9.
      "The human gene encoding SCYB9B, a putative novel CXC chemokine, maps to human chromosome 4q21 like the closely related genes for MIG (SCYB9) and INP10 (SCYB10)."
      Erdel M. , Laich A. , Utermann G. , Werner E.R. , Werner-Felmayer G.
      Cytogenet. Cell Genet.81:271-272(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] OF 28-84
    10. 10.
      "Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation."
      Loos T. , Mortier A. , Gouwy M. , Ronsse I. , Put W. , Lenaerts J.P. , Van Damme J. , Proost P.
      Blood112:2648-2656(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CITRULLINATION AT ARG-27
    11. 11.
      "NMR structure of CXCR3 binding chemokine CXCL11 (ITAC)."
      Booth V. , Clark-Lewis I. , Sykes B.D.
      Protein Sci.13:2022-2028(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 22-94;DISULFIDE BONDS
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