DAZ3 ELISA Kit for Human(Homo sapiens) | EIAab.comDAZ3 ELISA Kit for Human(Homo sapiens)

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DAZ3 (Gene name),

Deleted in azoospermia protein 3 (Protein name ), DAZ3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

DAZ3;

Protein name:

Deleted in azoospermia protein 3;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Forms a heterodimer with BOLL and DAZL. Interacts with PUM2, DAZAP1, DAZAP2, DZIP1 and DZIP3.

Function:

RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.

Subcellular Location:

Cytoplasm Nucleus Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.

Protein Attributes:

Sequence length:

486

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

486:

YNYQMPPQCP | VGEQRRNLWT | EAYKWWYLVC | LIQRRD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000371802

String:

Q9NR90

KEGG:

hsa:57054

MIM:

400027

UniGene:

Hs.592257

Pfam:

PF00076

SMR:

Q9NR90

Uniprot:

Q9NR90

FOR

ELISA Kit for Human Deleted in azoospermia protein 3

CLIA Kit for Human Deleted in azoospermia protein 3

Polyclonal Antibody for Human Deleted in azoospermia protein 3

Monoclonal Antibody for Human Deleted in azoospermia protein 3

Protein for Human Deleted in azoospermia protein 3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Four DAZ genes in two clusters found in the AZFc region of the human Y chromosome."
Saxena R. , de Vries J.W.A. , Repping S. , Alagappan R.K. , Skaletsky H. , Brown L.G. , Ma P. , Chen E. , Hoovers J.M.N. , Page D.C.
Genomics67:256-267(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);GENE STRUCTURE;GENE NOMENCLATURE;TISSUE SPECIFICITY
tissue: Testis.
2.

"The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes."
Skaletsky H. , Kuroda-Kawaguchi T. , Minx P.J. , Cordum H.S. , Hillier L.W. , Brown L.G. , Repping S. , Pyntikova T. , Ali J. , Bieri T. , Chinwalla A. , Delehaunty A. , Delehaunty K. , Du H. , Fewell G. , Fulton L. , Fulton R. , Graves T.A. , more...
Nature423:825-837(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
4.

"Identification of two novel proteins that interact with germ-cell-specific RNA-binding proteins DAZ and DAZL1."
Tsui S. , Dai T. , Roettger S. , Schempp W. , Salido E.C. , Yen P.H.
Genomics65:266-273(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DAZAP1 AND DAZAP2
5.

"DAZ family proteins exist throughout male germ cell development and transit from nucleus to cytoplasm at meiosis in humans and mice."
Reijo R.A. , Dorfman D.M. , Slee R. , Renshaw A.A. , Loughlin K.R. , Cooke H. , Page D.C.
Biol. Reprod.63:1490-1496(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
6.

"In vivo and in vitro analysis of homodimerisation activity of the mouse Dazl1 protein."
Ruggiu M. , Cooke H.J.
Gene252:119-126(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DAZL
7.

"A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans."
Xu E.Y. , Moore F.L. , Reijo Pera R.A.
Proc. Natl. Acad. Sci. U.S.A.98:7414-7419(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BOLL
8.

"Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins."
Moore F.L. , Jaruzelska J. , Fox M.S. , Urano J. , Firpo M.T. , Turek P.J. , Dorfman D.M. , Reijo Pera R.A.
Proc. Natl. Acad. Sci. U.S.A.100:538-543(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PUM2; DZIP1 AND DZIP3
9.

"Polymorphic DAZ gene family in polymorphic structure of AZFc locus: artwork or functional for human spermatogenesis?"
Vogt P.H. , Fernandes S.
APMIS111:115-127(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
10.

"Male infertility caused by a de novo partial deletion of the DAZ cluster on the Y chromosome."
Moro E. , Ferlin A. , Yen P.H. , Franchi P.G. , Palka G. , Foresta C.
J. Clin. Endocrinol. Metab.85:4069-4073(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN SPGFY2
11.

"Partial DAZ deletions in a family with five infertile brothers."
Gianotten J. , Hoffer M.J.V. , De Vries J.W.A. , Leschot N.J. , Gerris J. , van der Veen F.
Fertil. Steril.79:1652-1655(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN SPGFY2

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