Dazl ELISA Kit for Mouse(Mus musculus) | EIAab.comDazl ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Dazl(Gene name) > Mouse

Dazl (Gene name),

Deleted in azoospermia-like (Protein name ), DAZL_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Dazl(Dazl1;Dazla);

Protein name:

Deleted in azoospermia-like;

Alternative:

Deleted in azoospermia-like 1;DAZ-like autosomal;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer and heterodimer. Forms a heterodimer with DAZ. Interacts with BOLL, DAZAP1 and DAZAP2. Interacts with PUM2.

Function:

RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. May act by binding to the 3'-UTR of mRNA and thereby regulating the translation of key transcripts.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

298

Sequence:

50:

100:

150:

200:

250:

298:

SIQTVVSCLF | NPENRLRNSL | VTQDDYFKDK | RVHHFRRSRA | VLKSDHLC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q64368

UniGene:

Mm.280641

KEGG:

mmu:13164

Pfam:

PF00076

String:

Q64368

Uniprot:

Q64368

FOR

ELISA Kit for Mouse Deleted in azoospermia-like

CLIA Kit for Mouse Deleted in azoospermia-like

Polyclonal Antibody for Mouse Deleted in azoospermia-like

Monoclonal Antibody for Mouse Deleted in azoospermia-like

Protein for Mouse Deleted in azoospermia-like

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Isolation of a mouse homolog of the human DAZ (Deleted in Azoospermia) gene."
Maiwald R. , Luche R.M. , Epstein C.J.
Mamm. Genome7:628-628(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: CD-1.
tissue: Testis.
2.

"A murine homologue of the human DAZ gene is autosomal and expressed only in male and female gonads."
Cooke H.J. , Lee M. , Kerr S. , Ruggiu M.
Hum. Mol. Genet.5:513-516(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Testis.
3.

"Mouse autosomal homolog of DAZ, a candidate male sterility gene in humans, is expressed in male germ cells before and after puberty."
Reijo R.A. , Seligman J. , Dinulos M.B. , Jaffe T. , Brown L.G. , Disteche C.M. , Page D.C.
Genomics35:346-352(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: BALB/c.
tissue: Testis.
4.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6J.
tissue: Testis.
5.

"The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis."
Ruggiu M. , Speed R. , Taggart M. , McKay S.J. , Kilanowski F. , Saunders P.T.K. , Dorin J. , Cooke H.J.
Nature389:73-77(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
6.

"In vivo and in vitro analysis of homodimerisation activity of the mouse Dazl1 protein."
Ruggiu M. , Cooke H.J.
Gene252:119-126(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: HOMODIMERIZATION;INTERACTION WITH DAZ
7.

"The RNA-binding specificity of the mouse Dazl protein."
Venables J.P. , Ruggiu M. , Cooke H.J.
Nucleic Acids Res.29:2479-2483(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: RNA-BINDING;MUTAGENESIS OF PHE-43; TYR-82; PHE-84 AND PHE-87
8.

"Phosphoproteome analysis of mouse liver using immobilized metal affinity purification and linear ion trap mass spectrometry."
Jin W.-H. , Dai J. , Zhou H. , Xia Q.-C. , Zou H.-F. , Zeng R.
Rapid Commun. Mass Spectrom.18:2169-2176(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-276
9.

"Kinked beta-strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZL."
Jenkins H.T. , Malkova B. , Edwards T.A.
Proc. Natl. Acad. Sci. U.S.A.108:18266-18271(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.35 ANGSTROMS) OF 32-132 ALONE AND IN COMPLEX WITH RNA;FUNCTION;SUBUNIT

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