Dcp2 ELISA Kit for Mouse(Mus musculus) | EIAab.comDcp2 ELISA Kit for Mouse(Mus musculus)

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Dcp2 (Gene name),

mRNA-decapping enzyme 2 (Protein name ), DCP2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Dcp2;

Protein name:

mRNA-decapping enzyme 2;

Alternative:

mRNA-decapping enzyme 2;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Found in a mRNA decay complex with LSM1, LSM3, LSM4, EXOSC2, EXOSC4, EXOSC10, PARN, XRN1, CNOT6, UPF1, UPF2 and UPF3B. Forms a complex with DCP1A, EDC3, DDX6 and EDC4/HEDLS, within this complex directly interacts with EDC4/HEDLS. Interacts with DPC1B, UPF1, UPF2 and UPF3B. Associates with polysomes. Interacts (via N-terminus and C-terminus) with TRIM21 (via N-terminus and C-terminus).

Function:

Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Plays a role in replication-dependent histone mRNA degradation. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Has higher activity towards mRNAs that lack a poly(A) tail. Has no activity towards a cap structure lacking an RNA moiety.

Subcellular Location:

Cytoplasm P-body Nucleus Predominantly cytoplasmic, in processing bodies (PB). A minor amount is nuclear.

Protein Attributes:

Sequence length:

422

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