DCLRE1B ELISA Kit for Chicken(Gallus gallus) | EIAab.comDCLRE1B ELISA Kit for Chicken(Gallus gallus)

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Index > Protein center > DCLRE1B(Gene name) > Chicken

DCLRE1B (Gene name),

5' exonuclease Apollo (Protein name ), DCR1B_CHICK from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

DCLRE1B(SNM1B);

Protein name:

5' exonuclease Apollo;

Alternative:

SNM1 homolog B;DNA cross-link repair 1B protein;

Organism:

Chicken (Gallus gallus).

General Annotation

Sub Unit:

Interacts with TERF2; the interaction is direct.

Function:

5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase. Participates in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair, thereby ensuring that telomeres do not fuse. Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity: generates 3' single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres that are vulnerable to end-joining reactions and expose the telomere end in a manner that activates the DNA repair pathways (By similarity). May be required for DNA interstrand cross-link repair.

Subcellular Location:

Chromosome telomere Nucleus

Protein Attributes:

Sequence length:

457

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

457:

FIRWEPS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Gga.12786

Pfam:

PF07522

STRING:

9031.ENSGALP00000002949

String:

Q5QJC3

KEGG:

gga:428269

Uniprot:

Q5QJC3

FOR

ELISA Kit for Chicken 5' exonuclease Apollo

CLIA Kit for Chicken 5' exonuclease Apollo

Polyclonal Antibody for Chicken 5' exonuclease Apollo

Monoclonal Antibody for Chicken 5' exonuclease Apollo

Protein for Chicken 5' exonuclease Apollo

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation."
Ishiai M. , Kimura M. , Namikoshi K. , Yamazoe M. , Yamamoto K. , Arakawa H. , Agematsu K. , Matsushita N. , Takeda S. , Buerstedde J.-M. , Takata M.
Mol. Cell. Biol.24:10733-10741(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION

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