DCXR ELISA Kit for Human(Homo sapiens) | EIAab.comDCXR ELISA Kit for Human(Homo sapiens)

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DCXR (Gene name),

L-xylulose reductase (Protein name ), DCXR_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

DCXR;

Protein name:

L-xylulose reductase(XR);

Alternative:

Dicarbonyl/L-xylulose reductase;Carbonyl reductase II;Sperm surface protein P34H;Kidney dicarbonyl reductase(kiDCR);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homotetramer.

Function:

Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.

Subcellular Location:

Membrane Peripheral membrane protein Probably recruited to membranes via an interaction with phosphatidylinositol.

Protein Attributes:

Sequence length:

244

Sequence:

50:

100:

150:

200:

244:

LNRIPLGKFA | EVEHVVNAIL | FLLSDRSGMT | TGSTLPVEGG | FWAC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q7Z4W1

KEGG:

hsa:51181

STRING:

9606.ENSP00000303356

Pfam:

PF00106

UniGene:

Hs.9857

SMR:

Q7Z4W1

MIM:

608347

Uniprot:

Q7Z4W1

FOR

ELISA Kit for Human XR

CLIA Kit for Human XR

Polyclonal Antibody for Human XR

Monoclonal Antibody for Human XR

Protein for Human XR

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"P34H sperm protein is preferentially expressed by the human corpus epididymidis."
Legare C. , Gaudreault C. , St Jacques S. , Sullivan R.
Endocrinology140:3318-3327(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
tissue: Epididymis.
2.

"Molecular characterization of mammalian dicarbonyl/L-xylulose reductase and its localization in kidney."
Nakagawa J. , Ishikura S. , Asami J. , Isaji T. , Usami N. , Hara A. , Sakurai T. , Tsuritani K. , Oda K. , Takahashi M. , Yoshimoto M. , Otsuka N. , Kitamura K.
J. Biol. Chem.277:17883-17891(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];ENZYME ACTIVITY;TISSUE SPECIFICITY;INVOLVEMENT IN PNTSU
3.

"Molecular cloning of human sperm surface protein P34H gene and semi-quantitative analysis of its expression in testis and epididymidis."
Xia X.Y. , Xu X.F. , Gao Y. , Huang Y.F.
Zhonghua Nan Ke Xue9:24-27(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Epididymis.
tissue: Liver.
tissue: Testis.
4.

"A novel gene expressed in the human adrenal gland."
Huang C. , Li Y. , Wu T. , Peng Y. , Gu Y. , Zhang L. , Jiang C. , Zhang C. , Han Z. , Wang Y. , Chen Z. , Fu G.
Submitted (1998-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Adrenal gland.
5.

"Cloning and characterization of a new human cDNA of carbonyl reductase."
Liu Q. , Yu L. , Zhao S.Y.
Submitted (1999-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
6.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.
tissue: Placenta.
8.

"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
Gevaert K. , Goethals M. , Martens L. , Van Damme J. , Staes A. , Thomas G.R. , Vandekerckhove J.
Nat. Biotechnol.21:566-569(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-8;ACETYLATION AT MET-1
tissue: Platelet.
9.

"The enzymatic defect in essential pentosuria."
Wang Y.M. , Van Eys J.
N. Engl. J. Med.282:892-896(1970) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POSSIBLE INVOLVEMENT IN PNTSU
10.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.

"Garrod's fourth inborn error of metabolism solved by the identification of mutations causing pentosuria."
Pierce S.B. , Spurrell C.H. , Mandell J.B. , Lee M.K. , Zeligson S. , Bereman M.S. , Stray S.M. , Fokstuen S. , MacCoss M.J. , Levy-Lahad E. , King M.C. , Motulsky A.G.
Proc. Natl. Acad. Sci. U.S.A.108:18313-18317(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN PNTSU
12.

"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
14.

"Crystallization and preliminary crystallographic analysis of human L-xylulose reductase."
El-Kabbani O. , Chung R.P.-T. , Ishikura S. , Usami N. , Nakagawa J. , Hara A.
Acta Crystallogr. D58:1379-1380(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.96 ANGSTROMS)
15.

"Crystal structure of human L-xylulose reductase holoenzyme: probing the role of Asn107 with site-directed mutagenesis."
El-Kabbani O. , Ishikura S. , Darmanin C. , Carbone V. , Chung R.P.-T. , Usami N. , Hara A.
Proteins55:724-732(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.96 ANGSTROMS) IN COMPLEX WITH NADP AND SUBSTRATE;MUTAGENESIS OF ASN-107

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