DDB1 ELISA Kit for Chicken(Gallus gallus) | EIAab.comDDB1 ELISA Kit for Chicken(Gallus gallus) | EIAab.com

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DDB1 (Gene name),

DNA damage-binding protein 1 (Protein name ), DDB1_CHICK from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Related Databases

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Gene name:

DDB1(RCJMB04_6h2);

Protein name:

DNA damage-binding protein 1;

Alternative:

Damage-specific DNA-binding protein 1;DDB p127 subunit;UV-damaged DNA-binding factor;

Organism:

Chicken (Gallus gallus).

General Annotation

Sub Unit:

Component of the UV-DDB complex which includes DDB1 and DDB2. Component of numerous DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which consist of a core of DDB1, CUL4A or CUL4B and RBX1. DDB1 may recruit specific substrate targeting subunits to the DCX complex. These substrate targeting subunits are generally known as DCAF (DDB1- and CUL4-associated factor) or CDW (CUL4-DDB1-associated WD40-repeat) proteins.

Function:

Required for DNA repair. Binds to DDB2 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. Also appears to function as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the DCX E3 ubiquitin-protein ligase complex is determined by the variable substrate recognition component recruited by DDB1.

Subcellular Location:

Cytoplasm Nucleus

Protein Attributes:

Sequence length:

1140

Sequence:

50:

MSYNYVVTAQ | KPTAVNGCVT | GHFTSAEDLN | LLIAKNTRLE | IYVVTAEGLR |

100:

PVKEVGMYGK | TAVMELFRPK | GESKDLLFIL | TAKYNACILE | YKQNGDNIDI |

150:

ITRAHGNVQD | RIGRPSETGI | IGIIDPECRM | IGLRLYDGLF | KVIPLDRENK |

200:

ELKAFNIRLE | ELQVIDVKFL | YGCQAPTICF | VYQDPQGRHV | KTYEVSLREK |

250:

EFNKGPWKQE | NVEAEASMVI | AVPEPFGGAI | IIGQESITYH | NGDKYLAIAP |

300:

PIIKQSTIVC | HNRVDPNGSR | YLLGDMEGRL | FMLLLEKEEQ | MDGTVTLKDL |

350:

RVELLGETSI | AECLTYLDNG | VVFVGSRLGD | SQLVKLNVDS | NEQGSYVVAM |

400:

ETFTNLGPIV | DMCVVDLERQ | GQGQLVTCSG | AFKEGSLRII | RNGIGIHEHA |

450:

SIDLPGIKGL | WPLRSDSHRE | MDNMLVLSFV | GQTRVLMLNG | EEVEETELTG |

500:

FVDDQQTFFC | GNVAHQQLIQ | ITSASVRLVS | QEPKALVSEW | KEPNGKNISV |

550:

ASCNSNQVVV | AVGRALYYLE | IRPQELRQIN | CTEMEHEVAC | LDITPLGDTN |

600:

GMSPLCAIGL | WTDISARILK | LPSFELLHKE | MLGGEIIPRS | ILMTTFESSH |

650:

YLLCALGDGA | LFYFGLSLET | GLLSDRKKVT | LGTQPTVLRT | FRSLSTTNVF |

700:

ACSDRPTVIY | SSNHKLVFSN | VNLKEVNYMC | PLNSDGYPDS | LALANNSTLT |

750:

IGTIDEIQKL | HIRTVPLYES | PRKICYQEVS | QCFGVLSSRI | EVQDASGGTT |

800:

ALRPSASTQA | LSSSVSTSKL | FSSSTAPHET | SFGEEVEVHN | LLIIDQHTFE |

850:

VLHAHQFLQN | EYALSLVSCK | LGKDPNTYFI | VGTAMVYPEE | AEPKQGRIVV |

900:

FHYSDGKLQS | LAEKEVKGAV | YSMVEFNGKL | LASINSTVRL | YEWTAEKELR |

950:

TECNHYNNIM | ALYLKTKGDF | ILVGDLMRSV | LLLAYKPMEG | NFEEIARDFN |

1000:

PNWMSAVEIL | DDDNFLGAEN | AFNLFVCQKD | SAATTDEERQ | HLQEVGLSHL |

1050:

GEFVNVFCHG | SLVMQNLGET | STPTQGSVLF | GTVNGMIGLV | TSLSESWYNL |

1100:

LLDMQNRLNK | VIKSVGKIEH | SFWRSFHTER | KTEPATGFID | GDLIESFLDI |

1140:

SRPKMQEVVA | NLQIDDGSGM | KREATVDDLI | KIVEELTRIH |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

String:

UniGene:

Pfam:

STRING:

9031.ENSGALP00000039807

Uniprot:

FOR

ELISA Kit for Chicken DNA damage-binding protein 1

ELISA Kit for Chicken DNA damage-binding protein 1

ELISA Kit for Chicken DNA damage-binding protein 1

ELISA Kit for Chicken DNA damage-binding protein 1

ELISA Kit for Chicken DNA damage-binding protein 1

CLIA Kit for Chicken DNA damage-binding protein 1

CLIA Kit for Chicken DNA damage-binding protein 1

CLIA Kit for Chicken DNA damage-binding protein 1

CLIA Kit for Chicken DNA damage-binding protein 1

CLIA Kit for Chicken DNA damage-binding protein 1

Polyclonal Antibody for Chicken DNA damage-binding protein 1

Polyclonal Antibody for Chicken DNA damage-binding protein 1

Polyclonal Antibody for Chicken DNA damage-binding protein 1

Polyclonal Antibody for Chicken DNA damage-binding protein 1

Polyclonal Antibody for Chicken DNA damage-binding protein 1

Monoclonal Antibody for Chicken DNA damage-binding protein 1

Monoclonal Antibody for Chicken DNA damage-binding protein 1

Monoclonal Antibody for Chicken DNA damage-binding protein 1

Monoclonal Antibody for Chicken DNA damage-binding protein 1

Monoclonal Antibody for Chicken DNA damage-binding protein 1

Protein for Chicken DNA damage-binding protein 1

Protein for Chicken DNA damage-binding protein 1

Protein for Chicken DNA damage-binding protein 1

Protein for Chicken DNA damage-binding protein 1

Protein for Chicken DNA damage-binding protein 1

R&D Technical Data

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Precision

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Recovery

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Linearity

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References

1.

"cDNA cloning of the chicken DDB1 gene encoding the p127 subunit of damaged DNA-binding protein."
Fu D. , Wakasugi M. , Ishigaki Y. , Nikaido O. , Matsunaga T.
Genes Genet. Syst.78:169-177(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION
2.

"Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis."
Caldwell R.B. , Kierzek A.M. , Arakawa H. , Bezzubov Y. , Zaim J. , Fiedler P. , Kutter S. , Blagodatski A. , Kostovska D. , Koter M. , Plachy J. , Carninci P. , Hayashizaki Y. , Buerstedde J.-M.
Genome Biol.6:R6.1-R6.9(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: CB.
tissue: Bursa of Fabricius.
3.

"Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide."
Fischer E.S. , Bohm K. , Lydeard J.R. , Yang H. , Stadler M.B. , Cavadini S. , Nagel J. , Serluca F. , Acker V. , Lingaraju G.M. , Tichkule R.B. , Schebesta M. , Forrester W.C. , Schirle M. , Hassiepen U. , Ottl J. , Hild M. , Beckwith R.E. , more...
Nature512:49-53(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CRBN

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