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Index > Protein center > DDX23(Gene name) > Human
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  • DDX23 (Gene name),
  • Probable ATP-dependent RNA helicase DDX23 (Protein name ),  DDX23_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    DDX23;
    Protein name:
    Probable ATP-dependent RNA helicase DDX23;
    Alternative:
    DEAD box protein 23;100 kDa U5 snRNP-specific protein;U5-100kD;PRP28 homolog;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Component of the U5 and U5.4/6 snRNP complexes. Identified in the spliceosome C complex. Interacts with ERBB4.
    Function:
    Probably involved in pre-mRNA splicing.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    820
    Sequence:
    50:
    MAGELADKKD | RDASPSKEER | KRSRTPDRER | DRDRDRKSSP | SKDRKRHRSR | 
    100:
    DRRRGGSRSR | SRSRSKSAER | ERRHKERERD | KERDRNKKDR | DRDKDGHRRD | 
    150:
    KDRKRSSLSP | GRGKDFKSRK | DRDSKKDEED | EHGDKKPKAQ | PLSLEELLAK | 
    200:
    KKAEEEAEAK | PKFLSKAERE | AEALKRRQQE | VEERQRMLEE | ERKKRKQFQD | 
    250:
    LGRKMLEDPQ | ERERRERRER | MERETNGNED | EEGRQKIREE | KDKSKELHAI | 
    300:
    KERYLGGIKK | RRRTRHLNDR | KFVFEWDASE | DTSIDYNPLY | KERHQVQLLG | 
    350:
    RGFIAGIDLK | QQKREQSRFY | GDLMEKRRTL | EEKEQEEARL | RKLRKKEAKQ | 
    400:
    RWDDRHWSQK | KLDEMTDRDW | RIFREDYSIT | TKGGKIPNPI | RSWKDSSLPP | 
    450:
    HILEVIDKCG | YKEPTPIQRQ | AIPIGLQNRD | IIGVAETGSG | KTAAFLIPLL | 
    500:
    VWITTLPKID | RIEESDQGPY | AIILAPTREL | AQQIEEETIK | FGKPLGIRTV | 
    550:
    AVIGGISRED | QGFRLRMGCE | IVIATPGRLI | DVLENRYLVL | SRCTYVVLDE | 
    600:
    ADRMIDMGFE | PDVQKILEHM | PVSNQKPDTD | EAEDPEKMLA | NFESGKHKYR | 
    650:
    QTVMFTATMP | PAVERLARSY | LRRPAVVYIG | SAGKPHERVE | QKVFLMSESE | 
    700:
    KRKKLLAILE | QGFDPPIIIF | VNQKKGCDVL | AKSLEKMGYN | ACTLHGGKGQ | 
    750:
    EQREFALSNL | KAGAKDILVA | TDVAGRGIDI | QDVSMVVNYD | MAKNIEDYIH | 
    800:
    RIGRTGRAGK | SGVAITFLTK | EDSAVFYELK | QAILESPVSS | CPPELANHPD | 
    820:
    AQHKPGTILT | KKRREETIFA | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    SMR:
    MIM:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Probable ATP-dependent RNA helicase DDX23
    CLIA Kit for Human Probable ATP-dependent RNA helicase DDX23
    Polyclonal Antibody for Human Probable ATP-dependent RNA helicase DDX23
    Monoclonal Antibody for Human Probable ATP-dependent RNA helicase DDX23
    Protein for Human Probable ATP-dependent RNA helicase DDX23

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "The human U5 snRNP-specific 100-kD protein is an RS domain-containing, putative RNA helicase with significant homology to the yeast splicing factor Prp28p."
      Teigelkamp S. , Mundt C. , Achsel T. , Will C.L. , Luehrmann R.
      RNA3:1313-1326(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 272-290; 409-419 AND 433-441;SUBCELLULAR LOCATION;PHOSPHORYLATION;IDENTIFICATION IN U5 AND U5/4/6 SNRNP COMPLEXES
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Amygdala.
      tissue: Brain.
    3. 3.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Lung.
    6. 6.
      "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis."
      Jurica M.S. , Licklider L.J. , Gygi S.P. , Grigorieff N. , Moore M.J.
      RNA8:426-439(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE SPLICEOSOMAL C COMPLEX
    7. 7.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 8.
      "The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP."
      Liu S. , Rauhut R. , Vornlocher H.-P. , Luehrmann R.
      RNA12:1418-1430(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
    9. 9.
      "Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome."
      Mathew R. , Hartmuth K. , Moehlmann S. , Urlaub H. , Ficner R. , Luehrmann R.
      Nat. Struct. Mol. Biol.15:435-443(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PHOSPHORYLATION BY SRPK2
    10. 10.
      "Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways."
      Gilmore-Hebert M. , Ramabhadran R. , Stern D.F.
      Mol. Cancer Res.8:1388-1398(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;INTERACTION WITH ERBB4;SUBCELLULAR LOCATION
    11. 11.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-14 AND SER-16;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-14; SER-107 AND SER-109;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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