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Index > Protein center > DDX6(Gene name) > Human
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  • DDX6 (Gene name),
  • Probable ATP-dependent RNA helicase DDX6 (Protein name ),  DDX6_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    DDX6(HLR2;RCK);
    Protein name:
    Probable ATP-dependent RNA helicase DDX6;
    Alternative:
    DEAD box protein 6;ATP-dependent RNA helicase p54;Oncogene RCK;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Forms a complex with DCP1A, DCP2, EDC3 and EDC4/HEDLS.
    Function:
    In the process of mRNA degradation, may play a role in mRNA decapping.
    Subcellular Location:
    Cytoplasm P-body Processing bodies.
    Protein Attributes:
    Sequence length:
    483
    Sequence:
    50:
    MSTARTENPV | IMGLSSQNGQ | LRGPVKPTGG | PGGGGTQTQQ | QMNQLKNTNT | 
    100:
    INNGTQQQAQ | SMTTTIKPGD | DWKKTLKLPP | KDLRIKTSDV | TSTKGNEFED | 
    150:
    YCLKRELLMG | IFEMGWEKPS | PIQEESIPIA | LSGRDILARA | KNGTGKSGAY | 
    200:
    LIPLLERLDL | KKDNIQAMVI | VPTRELALQV | SQICIQVSKH | MGGAKVMATT | 
    250:
    GGTNLRDDIM | RLDDTVHVVI | ATPGRILDLI | KKGVAKVDHV | QMIVLDEADK | 
    300:
    LLSQDFVQIM | EDIILTLPKN | RQILLYSATF | PLSVQKFMNS | HLQKPYEINL | 
    350:
    MEELTLKGVT | QYYAYVTERQ | KVHCLNTLFS | RLQINQSIIF | CNSSQRVELL | 
    400:
    AKKISQLGYS | CFYIHAKMRQ | EHRNRVFHDF | RNGLCRNLVC | TDLFTRGIDI | 
    450:
    QAVNVVINFD | FPKLAETYLH | RIGRSGRFGH | LGLAINLITY | DDRFNLKSIE | 
    483:
    EQLGTEIKPI | PSNIDKSLYV | AEYHSEPVED | EKP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    SMR:
    MIM:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Probable ATP-dependent RNA helicase DDX6
    ELISA Kit for Human Probable ATP-dependent RNA helicase DDX6
    ELISA Kit for Human Probable ATP-dependent RNA helicase DDX6
    CLIA Kit for Human Probable ATP-dependent RNA helicase DDX6
    CLIA Kit for Human Probable ATP-dependent RNA helicase DDX6
    CLIA Kit for Human Probable ATP-dependent RNA helicase DDX6
    Polyclonal Antibody for Human Probable ATP-dependent RNA helicase DDX6
    Polyclonal Antibody for Human Probable ATP-dependent RNA helicase DDX6
    Polyclonal Antibody for Human Probable ATP-dependent RNA helicase DDX6
    Monoclonal Antibody for Human Probable ATP-dependent RNA helicase DDX6
    Monoclonal Antibody for Human Probable ATP-dependent RNA helicase DDX6
    Monoclonal Antibody for Human Probable ATP-dependent RNA helicase DDX6
    Protein for Human Probable ATP-dependent RNA helicase DDX6
    Protein for Human Probable ATP-dependent RNA helicase DDX6
    Protein for Human Probable ATP-dependent RNA helicase DDX6

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning, expression and localization of an RNA helicase gene from a human lymphoid cell line with chromosomal breakpoint 11q23.3."
      Lu D. , Yunis J.J.
      Nucleic Acids Res.20:1967-1972(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Skin.
    3. 3.
      "The RCK gene associated with t(11;14) translocation is distinct from the MLL/ALL-1 gene with t(4;11) and t(11;19) translocations."
      Akao Y. , Seto M. , Yamamoto K. , Iida S. , Nakazawa S. , Inazawa J. , Abe T. , Takahashi T. , Ueda R.
      Cancer Res.52:6083-6087(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 12-483
      tissue: Lung.
    4. 4.
      "Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping."
      Fenger-Groen M. , Fillman C. , Norrild B. , Lykke-Andersen J.
      Mol. Cell20:905-915(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;INTERACTION WITH DCP1A; DCP2; EDC3 AND EDC4;SUBCELLULAR LOCATION
    5. 5.
      "Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies."
      Wichroski M.J. , Robb G.B. , Rana T.M.
      PLoS Pathog.2:E41-E41(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH APOBEC3G
    6. 6.
      "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
      Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
      Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-36;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic kidney.
    7. 7.
      "LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing."
      James V. , Zhang Y. , Foxler D.E. , de Moor C.H. , Kong Y.W. , Webb T.M. , Self T.J. , Feng Y. , Lagos D. , Chu C.Y. , Rana T.M. , Morley S.J. , Longmore G.D. , Bushell M. , Sharp T.V.
      Proc. Natl. Acad. Sci. U.S.A.107:12499-12504(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH LIMD1; WTIP AND AJUBA
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      "HIV-1 replication and APOBEC3 antiviral activity are not regulated by P bodies."
      Phalora P.K. , Sherer N.M. , Wolinsky S.M. , Swanson C.M. , Malim M.H.
      J. Virol.86:11712-11724(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    10. 10.
      "Crystallization and X-ray analysis of the N-terminal core domain of a tumour-associated human DEAD-box RNA helicase, rck/p54."
      Matsui T. , Hogetsu K. , Akao Y. , Tanaka M. , Sato T. , Kumasaka T. , Tanaka N.
      Acta Crystallogr. D60:156-159(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 94-299
    11. 11.
      "Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral to the DEAD box protein DDX6/Me31B."
      Tritschler F. , Braun J.E. , Eulalio A. , Truffault V. , Izaurralde E. , Weichenrieder O.
      Mol. Cell33:661-668(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 296-483 IN COMPLEX WITH EDC3;MUTAGENESIS OF GLN-320; HIS-323; THR-327 AND ARG-331;INTERACTION WITH EDC3
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