Defa6 ELISA Kit for Mouse(Mus musculus) | EIAab.comDefa6 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Defa6(Gene name) > Mouse

Defa6 (Gene name),

Alpha-defensin 6/12 (Protein name ), DEFA6_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Defa6(Defcr6);

Protein name:

Alpha-defensin 6/12;

Alternative:

Defensin-related cryptdin-6/12(Cryptdin-2);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Has broad-spectrum antimicrobial properties. Has antibacterial activity against the Gram-positive bacterium L.monocytogenes EGD and the Gram-negative bacteria E.coli ML-35p and avirulent S.typhimurium 7953, but not against the mouse-virulent S.typhimurium 14028S. Probably contributes to the antimicrobial barrier function of the small bowel mucosa.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

Sequence:

50:

93:

GTSLQEESLR | DLVCYCRARG | CKGRERMNGT | CRKGHLLYML | CCR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.426552

SMR:

P50704

Pfam:

PF00323

KEGG:

mmu:13240

String:

P50704

Uniprot:

P50704

FOR

ELISA Kit for Mouse Alpha-defensin 6/12

CLIA Kit for Mouse Alpha-defensin 6/12

Polyclonal Antibody for Mouse Alpha-defensin 6/12

Monoclonal Antibody for Mouse Alpha-defensin 6/12

Protein for Mouse Alpha-defensin 6/12

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Structure and diversity of the murine cryptdin gene family."
Huttner K.M. , Selsted M.E. , Ouellette A.J.
Genomics19:448-453(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (DEFA6);NUCLEOTIDE SEQUENCE [MRNA] OF 59-93 (DEFCR12)
strain: 129.
strain: C3H/HeJ.
tissue: Intestinal epithelium.
2.

"Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms."
Ouellette A.J. , Hsieh M.M. , Nosek M.T. , Cano-Gauci D.F. , Huttner K.M. , Buick R.N. , Selsted M.E.
Infect. Immun.62:5040-5047(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (DEFA6 AND DEFA12);FUNCTION
strain: CD-1.
tissue: Intestinal crypt.
3.

"Cryptdins: antimicrobial defensins of the murine small intestine."
Eisenhauer P.B. , Harwig S.S.S.L. , Lehrer R.I.
Infect. Immun.60:3556-3565(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 59-93;FUNCTION
strain: Swiss Webster.
tissue: Small intestine.

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