Protein name:
Diacylglycerol O-acyltransferase 1 ;
Alternative:
Diglyceride acyltransferase ;2.3.1.76;Diglyceride acyltransferase (ARAT) ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Homodimer or homotetramer.
Function:
Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly.
Subcellular Location:
Endoplasmic reticulum membrane
Multi-pass membrane protein
Protein Attributes:
50:
MGDRGGAGGS | RRRRTGSRPS | IQGGSGPAAA | EEEVRDVGAG | GDAPVRDTDK |
100:
DGDVDVGSGH | WDLRCHRLQD | SLFSSDSGFS | NYRGILNWCV | VMLILSNARL |
150:
FLENLIKYGI | LVDPIQVVSL | FLKDPYSWPA | LCLVIVANIF | AVAAFQVEKR |
200:
LAVGALTEQA | GLLLHGVNLA | TILCFPAAVA | FLLESITPVG | SVLALMVYTI |
250:
LFLKLFSYRD | VNLWCRERRA | GAKAKAALAG | KKANGGAAQR | TVSYPDNLTY |
300:
RDLYYFLFAP | TLCYELNFPR | SPRIRKRFLL | RRLLEMLFLT | QLQVGLIQQW |
350:
MVPAIQNSMK | PFKDMDYSRI | VERLLKLAVP | NHLIWLIFFY | WLFHSCLNAV |
400:
AELMQFGDRE | FYRDWWNSES | ITYFWQNWNI | PVHKWCIRHF | YKPMLRRGSS |
450:
KWAARTAVFL | ASAFFHEYLV | SIPLRMFRLW | AFTGMMAQIP | LAWIVGRFFR |
489:
GNYGNAAVWL | SLIIGQPVAV | LMYVHDYYVL | NREAPAAGT
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Rat
Mouse
ELISA Kit for Bovine Diacylglycerol O-acyltransferase 1
ELISA Kit for Bovine Diacylglycerol O-acyltransferase 1
ELISA Kit for Bovine Diacylglycerol O-acyltransferase 1
ELISA Kit for Bovine Diacylglycerol O-acyltransferase 1
CLIA Kit for Bovine Diacylglycerol O-acyltransferase 1
CLIA Kit for Bovine Diacylglycerol O-acyltransferase 1
CLIA Kit for Bovine Diacylglycerol O-acyltransferase 1
CLIA Kit for Bovine Diacylglycerol O-acyltransferase 1
Polyclonal Antibody for Bovine Diacylglycerol O-acyltransferase 1
Polyclonal Antibody for Bovine Diacylglycerol O-acyltransferase 1
Polyclonal Antibody for Bovine Diacylglycerol O-acyltransferase 1
Polyclonal Antibody for Bovine Diacylglycerol O-acyltransferase 1
Monoclonal Antibody for Bovine Diacylglycerol O-acyltransferase 1
Monoclonal Antibody for Bovine Diacylglycerol O-acyltransferase 1
Monoclonal Antibody for Bovine Diacylglycerol O-acyltransferase 1
Monoclonal Antibody for Bovine Diacylglycerol O-acyltransferase 1
Protein for Bovine Diacylglycerol O-acyltransferase 1
Protein for Bovine Diacylglycerol O-acyltransferase 1
Protein for Bovine Diacylglycerol O-acyltransferase 1
Protein for Bovine Diacylglycerol O-acyltransferase 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Positional candidate cloning of a QTL in dairy cattle: identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition."
Grisart B.
,
Coppieters W.
,
Farnir F.
,
Karim L.
,
Ford C.
,
Berzi P.
,
Cambisano N.
,
Mni M.
,
Reid S.
,
Simon P.
,
Spelman R.
,
Georges M.
,
Snell R.
Genome Res.12:222-231(2002)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ALA-232
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ALA-232
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ALA-232
strain :
Hereford .
tissue :
Ascending colon .