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Index > Protein center > DGAT1(Gene name) > Bovine
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  • DGAT1 (Gene name),
  • Diacylglycerol O-acyltransferase 1 (Protein name ),  DGAT1_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    DGAT1;
    Protein name:
    Diacylglycerol O-acyltransferase 1;
    Alternative:
    Diglyceride acyltransferase;2.3.1.76;Diglyceride acyltransferase(ARAT);
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Homodimer or homotetramer.
    Function:
    Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    489
    Sequence:
    50:
    MGDRGGAGGS | RRRRTGSRPS | IQGGSGPAAA | EEEVRDVGAG | GDAPVRDTDK | 
    100:
    DGDVDVGSGH | WDLRCHRLQD | SLFSSDSGFS | NYRGILNWCV | VMLILSNARL | 
    150:
    FLENLIKYGI | LVDPIQVVSL | FLKDPYSWPA | LCLVIVANIF | AVAAFQVEKR | 
    200:
    LAVGALTEQA | GLLLHGVNLA | TILCFPAAVA | FLLESITPVG | SVLALMVYTI | 
    250:
    LFLKLFSYRD | VNLWCRERRA | GAKAKAALAG | KKANGGAAQR | TVSYPDNLTY | 
    300:
    RDLYYFLFAP | TLCYELNFPR | SPRIRKRFLL | RRLLEMLFLT | QLQVGLIQQW | 
    350:
    MVPAIQNSMK | PFKDMDYSRI | VERLLKLAVP | NHLIWLIFFY | WLFHSCLNAV | 
    400:
    AELMQFGDRE | FYRDWWNSES | ITYFWQNWNI | PVHKWCIRHF | YKPMLRRGSS | 
    450:
    KWAARTAVFL | ASAFFHEYLV | SIPLRMFRLW | AFTGMMAQIP | LAWIVGRFFR | 
    489:
    GNYGNAAVWL | SLIIGQPVAV | LMYVHDYYVL | NREAPAAGT
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Diacylglycerol O-acyltransferase 1
    ELISA Kit for Bovine Diacylglycerol O-acyltransferase 1
    ELISA Kit for Bovine Diacylglycerol O-acyltransferase 1
    ELISA Kit for Bovine Diacylglycerol O-acyltransferase 1
    CLIA Kit for Bovine Diacylglycerol O-acyltransferase 1
    CLIA Kit for Bovine Diacylglycerol O-acyltransferase 1
    CLIA Kit for Bovine Diacylglycerol O-acyltransferase 1
    CLIA Kit for Bovine Diacylglycerol O-acyltransferase 1
    Polyclonal Antibody for Bovine Diacylglycerol O-acyltransferase 1
    Polyclonal Antibody for Bovine Diacylglycerol O-acyltransferase 1
    Polyclonal Antibody for Bovine Diacylglycerol O-acyltransferase 1
    Polyclonal Antibody for Bovine Diacylglycerol O-acyltransferase 1
    Monoclonal Antibody for Bovine Diacylglycerol O-acyltransferase 1
    Monoclonal Antibody for Bovine Diacylglycerol O-acyltransferase 1
    Monoclonal Antibody for Bovine Diacylglycerol O-acyltransferase 1
    Monoclonal Antibody for Bovine Diacylglycerol O-acyltransferase 1
    Protein for Bovine Diacylglycerol O-acyltransferase 1
    Protein for Bovine Diacylglycerol O-acyltransferase 1
    Protein for Bovine Diacylglycerol O-acyltransferase 1
    Protein for Bovine Diacylglycerol O-acyltransferase 1

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    References
    1. 1.
      "Positional candidate cloning of a QTL in dairy cattle: identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition."
      Grisart B. , Coppieters W. , Farnir F. , Karim L. , Ford C. , Berzi P. , Cambisano N. , Mni M. , Reid S. , Simon P. , Spelman R. , Georges M. , Snell R.
      Genome Res.12:222-231(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ALA-232
    2. 2.
      "Association of a lysine-232/alanine polymorphism in a bovine gene encoding acyl-CoA:diacylglycerol acyltransferase (DGAT1) with variation at a quantitative trait locus for milk fat content."
      Winter A. , Kramer W. , Werner F.A.O. , Kollers S. , Kata S. , Durstewitz G. , Buitkamp J. , Womack J.E. , Thaller G. , Fries R.
      Proc. Natl. Acad. Sci. U.S.A.99:9300-9305(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ALA-232
    3. 3.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2006-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ALA-232
      strain: Hereford.
      tissue: Ascending colon.
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