Protein name:
Diacylglycerol O-acyltransferase 1 ;
Alternative:
Diglyceride acyltransferase ;2.3.1.76;Diglyceride acyltransferase (ARAT) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homodimer or homotetramer.
Function:
Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly.
Subcellular Location:
Endoplasmic reticulum membrane
Multi-pass membrane protein
Protein Attributes:
50:
MGDRGGAGSS | RRRRTGSRVS | VQGGSGPKVE | EDEVRDAAVS | PDLGAGGDAP |
100:
APAPAPAHTR | DKDGRTSVGD | GYWDLRCHRL | QDSLFSSDSG | FSNYRGILNW |
150:
CVVMLILSNA | RLFLENLIKY | GILVDPIQVV | SLFLKDPYSW | PAPCVIIASN |
200:
IFVVAAFQIE | KRLAVGALTE | QMGLLLHVVN | LATIICFPAA | VALLVESITP |
250:
VGSVFALASY | SIMFLKLYSY | RDVNLWCRQR | RVKAKAVSTG | KKVSGAAAQQ |
300:
AVSYPDNLTY | RDLYYFIFAP | TLCYELNFPR | SPRIRKRFLL | RRVLEMLFFT |
350:
QLQVGLIQQW | MVPTIQNSMK | PFKDMDYSRI | IERLLKLAVP | NHLIWLIFFY |
400:
WFFHSCLNAV | AELLQFGDRE | FYRDWWNAES | VTYFWQNWNI | PVHKWCIRHF |
450:
YKPMLRHGSS | KWVARTGVFL | TSAFFHEYLV | SVPLRMFRLW | AFTAMMAQVP |
498:
LAWIVGRFFQ | GNYGNAAVWV | TLIIGQPVAV | LMYVHDYYVL | NYDAPVGV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Rat
Mouse
ELISA Kit for Mouse Diacylglycerol O-acyltransferase 1
ELISA Kit for Mouse Diacylglycerol O-acyltransferase 1
ELISA Kit for Mouse Diacylglycerol O-acyltransferase 1
ELISA Kit for Mouse Diacylglycerol O-acyltransferase 1
CLIA Kit for Mouse Diacylglycerol O-acyltransferase 1
CLIA Kit for Mouse Diacylglycerol O-acyltransferase 1
CLIA Kit for Mouse Diacylglycerol O-acyltransferase 1
CLIA Kit for Mouse Diacylglycerol O-acyltransferase 1
Polyclonal Antibody for Mouse Diacylglycerol O-acyltransferase 1
Polyclonal Antibody for Mouse Diacylglycerol O-acyltransferase 1
Polyclonal Antibody for Mouse Diacylglycerol O-acyltransferase 1
Polyclonal Antibody for Mouse Diacylglycerol O-acyltransferase 1
Monoclonal Antibody for Mouse Diacylglycerol O-acyltransferase 1
Monoclonal Antibody for Mouse Diacylglycerol O-acyltransferase 1
Monoclonal Antibody for Mouse Diacylglycerol O-acyltransferase 1
Monoclonal Antibody for Mouse Diacylglycerol O-acyltransferase 1
Protein for Mouse Diacylglycerol O-acyltransferase 1
Protein for Mouse Diacylglycerol O-acyltransferase 1
Protein for Mouse Diacylglycerol O-acyltransferase 1
Protein for Mouse Diacylglycerol O-acyltransferase 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis."
Cases S.
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PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
C57BL/6 .
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"The transcriptional landscape of the mammalian genome."
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Tongue .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION PHENOTYPE
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CATALYTIC ACTIVITY;FUNCTION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : MUTAGENESIS OF HIS-426;SUBUNIT;CATALYTIC ACTIVITY;SUBCELLULAR LOCATION;MEMBRANE TOPOLOGY;FUNCTION
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION