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Index > Protein center > Dagla(Gene name) > Mouse
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  • Dagla (Gene name),
  • Sn1-specific diacylglycerol lipase alpha (Protein name ),  DGLA_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Dagla(Kiaa0659;Nsddr);
    Protein name:
    Sn1-specific diacylglycerol lipase alpha(DGL-alpha);
    Alternative:
    Neural stem cell-derived dendrite regulator;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1044
    Sequence:
    50:
    MPGIVVFRRR | WSVGSDDLVL | PAIFLFLLHT | TWFVILSVVL | FGLVYNPHEA | 
    100:
    CSLNLVDHGR | GYLGILLSCM | IAEMAIIWLS | MRGGILYTEP | RDSMQYVLYV | 
    150:
    RLAILVIEFI | YAIVGIVWLT | QYYTSCNDLT | AKNVTLGMVV | CNWVVILSVC | 
    200:
    ITVLCVFDPT | GRTFVKLRAT | KRRQRNLRTY | NLRHRLEEGQ | ATSWSRRLKV | 
    250:
    FLCCTRTKDS | QSDAYSEIAY | LFAEFFRDLD | IVPSDIIAGL | VLLRQRQRAK | 
    300:
    RNAVLDEANN | DILAFLSGMP | VTRNTKYLDL | KNSHEMLRYK | EVCYYMLFAL | 
    350:
    AAYGWPMYLM | RKPTCGLCQL | ARSCSCCLCP | ARPRFAPGVT | IEEDNCCGCN | 
    400:
    AIAIRRHFLD | ENMTAVDIVY | TSCHDAVYET | PFYVAVDHDK | KKVVISIRGT | 
    450:
    LSPKDALTDL | TGDAERLPVE | GHRGTWLGHK | GMVLSAEYIK | KKLEQEMVLS | 
    500:
    QAFGRDLGRG | TKHYGLIVVG | HSLGAGTAAI | LSFLLRPQYP | TLKCFAYSPP | 
    550:
    GGLLSEDAME | YSKEFVTAVV | LGKDLVPRIG | LSQLEGFRRQ | LLDVLQRSTK | 
    600:
    PKWRIIVGAT | KCIPKSELPE | DQVEVTTLAS | TRLWTHPSDL | TIALSASTPL | 
    650:
    YPPGRIIHVV | HNHPAEQCCC | CEQEEPTYFA | IWGDNKAFNE | VIISPAMLHE | 
    700:
    HLPYVVMEGL | NKVLENYNKG | KTALLSAAKV | MVSPTEVDLT | PELIFQQQPL | 
    750:
    PTGPPLPTGL | ALELPATEHR | NSSVRSKSQS | EMSLEGFSEG | RLLSPVAAAS | 
    800:
    AARQDPVELL | LLSTQERLAA | ELQSRRAPLA | TMESLSDTES | LYSFDSRRSS | 
    850:
    GFRSIRGSPS | LHAVLERDEG | HLFYIDPAIP | EENPSLSSRT | ELLAADSLSK | 
    900:
    HSQDTQPLEA | ALGSGGVTPE | RPPSATIEEE | EAAGGSEGGG | VAPRGELALH | 
    950:
    NGRLGDSPSP | QVLEFAEFID | SLFNLDSKSS | SFQDLYCMMV | PESPTSDYTE | 
    1000:
    GPKSPSQQEI | LLRAQFEPNL | VPKPPRLFAG | SAEPSSGISL | SPSFPLSSSG | 
    1044:
    ELMDLTPTGL | SSQECLATDK | IRTSTPTGHG | ASPTKQDDLV | ISAR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse DGL-alpha
    ELISA Kit for Mouse DGL-alpha
    ELISA Kit for Mouse DGL-alpha
    CLIA Kit for Mouse DGL-alpha
    CLIA Kit for Mouse DGL-alpha
    CLIA Kit for Mouse DGL-alpha
    Polyclonal Antibody for Mouse DGL-alpha
    Polyclonal Antibody for Mouse DGL-alpha
    Polyclonal Antibody for Mouse DGL-alpha
    Monoclonal Antibody for Mouse DGL-alpha
    Monoclonal Antibody for Mouse DGL-alpha
    Monoclonal Antibody for Mouse DGL-alpha
    Protein for Mouse DGL-alpha
    Protein for Mouse DGL-alpha
    Protein for Mouse DGL-alpha

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "NSDDR a novel tetra-spanning transmembrane protein with a unique integration pattern to the plasma membrane regulates the extension of the dendritic trees of Purkinje cells."
      Horiguchi S. , Tashiro K. , Takahashi J. , Hashimoto N. , Nakano I. , Tsuchida Y. , Hirai H. , Honjo T.
      Submitted (2003-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6J.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Nagase T. , Ohara O. , Koga H.
      DNA Res.10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 894-1044
      tissue: Brain.
    4. 4.
      "Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain."
      Bisogno T. , Howell F. , Williams G. , Minassi A. , Cascio M.G. , Ligresti A. , Matias I. , Schiano-Moriello A. , Paul P. , Williams E.-J. , Gangadharan U. , Hobbs C. , Di Marzo V. , Doherty P.
      J. Cell Biol.163:463-468(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    5. 5.
      "Molecular composition of the endocannabinoid system at glutamatergic synapses."
      Katona I. , Urban G.M. , Wallace M. , Ledent C. , Jung K.M. , Piomelli D. , Mackie K. , Freund T.F.
      J. Neurosci.26:5628-5637(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    6. 6.
      "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
      Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
      Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-733 AND SER-744;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
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