Gene name:
Hsd17b11 (Dhrs8) ;
Protein name:
Estradiol 17-beta-dehydrogenase 11 ;
Alternative:
17-beta-hydroxysteroid dehydrogenase XI (17-beta-HSD XI;17betaHSDXI) ;17-beta-hydroxysteroid dehydrogenase 11 (17-beta-HSD 11;17bHSD11;17betaHSD11) ;Dehydrogenase/reductase SDR family member 8 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione.
Subcellular Location:
Secreted
Protein Attributes:
50:
MKYLLDLILL | LPLLIVFCIE | SFIKRLIPKK | KKSVAGEIVL | ITGAGHGIGR |
100:
LTAYEFAKLN | TKLVLWDINK | NGIEETAAKC | RKLGAQVHPF | VVDCSQREEI |
150:
YSAVRKVKEE | VGDVSILVNN | AGVVYTADLF | ATQDPQIEKT | FEVNVLAHFW |
200:
TTKAFLPAMM | KNNHGHVVTV | ASAAGHTVVP | FLLAYCSSKF | AAVGFHRALT |
250:
DELAALGCTG | VRTSCLCPNF | INTGFIKNPS | TNLGPTLEPE | EVVEHLMHGI |
298:
LTNQKMIFVP | GSIALLTVLE | RVFPERFLDV | LKRRINVKFD | AVVGYKDK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Human
ELISA Kit for Rat Estradiol 17-beta-dehydrogenase 11
ELISA Kit for Rat Estradiol 17-beta-dehydrogenase 11
ELISA Kit for Rat Estradiol 17-beta-dehydrogenase 11
CLIA Kit for Rat Estradiol 17-beta-dehydrogenase 11
CLIA Kit for Rat Estradiol 17-beta-dehydrogenase 11
CLIA Kit for Rat Estradiol 17-beta-dehydrogenase 11
Polyclonal Antibody for Rat Estradiol 17-beta-dehydrogenase 11
Polyclonal Antibody for Rat Estradiol 17-beta-dehydrogenase 11
Polyclonal Antibody for Rat Estradiol 17-beta-dehydrogenase 11
Monoclonal Antibody for Rat Estradiol 17-beta-dehydrogenase 11
Monoclonal Antibody for Rat Estradiol 17-beta-dehydrogenase 11
Monoclonal Antibody for Rat Estradiol 17-beta-dehydrogenase 11
Protein for Rat Estradiol 17-beta-dehydrogenase 11
Protein for Rat Estradiol 17-beta-dehydrogenase 11
Protein for Rat Estradiol 17-beta-dehydrogenase 11
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Kidney .