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Index > Protein center > Hsd17b12(Gene name) > Mouse
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  • Hsd17b12 (Gene name),
  • Estradiol 17-beta-dehydrogenase 12 (Protein name ),  DHB12_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Hsd17b12(Kik1);
    Protein name:
    Estradiol 17-beta-dehydrogenase 12;
    Alternative:
    1.3.1.-;3-ketoacyl-CoA reductase(KAR);17-beta-hydroxysteroid dehydrogenase 12(17-beta-HSD 12);KIK-I;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in females. Also has 3-ketoacyl-CoA reductase activity, reducing both long chain 3-ketoacyl-CoAs and long chain fatty acyl-CoAs, suggesting a role in long fatty acid elongation.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    312
    Sequence:
    50:
    MECAPPAAGF | LYWVGASTIA | YLALRASYSL | FRAFQVWCVG | NEALVGPRLG | 
    100:
    EWAVVTGGTD | GIGKAYAEEL | AKRGMKIVLI | SRSQDKLNQV | SNNIKEKFNV | 
    150:
    ETRTIAVDFS | LDDIYDKIKT | GLSGLEIGVL | VNNVGMSYEY | PEYFLEIPDL | 
    200:
    DNTIKKLINI | NVLSVCKVTR | LVLPGMVERS | KGVILNISSA | SGMLPVPLLT | 
    250:
    IYSATKAFVD | FFSQCLHEEY | KSKGIFVQSV | MPYLVATKLA | KIQKPTLDKP | 
    300:
    SAETFVKSAI | KTVGLQTRTT | GYVIHSLMGS | INSIMPRWMY | FKIIMGFSKS | 
    312:
    LRNRYLKKRK | KN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    SMR:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Estradiol 17-beta-dehydrogenase 12
    ELISA Kit for Mouse Estradiol 17-beta-dehydrogenase 12
    ELISA Kit for Mouse Estradiol 17-beta-dehydrogenase 12
    ELISA Kit for Mouse Estradiol 17-beta-dehydrogenase 12
    CLIA Kit for Mouse Estradiol 17-beta-dehydrogenase 12
    CLIA Kit for Mouse Estradiol 17-beta-dehydrogenase 12
    CLIA Kit for Mouse Estradiol 17-beta-dehydrogenase 12
    CLIA Kit for Mouse Estradiol 17-beta-dehydrogenase 12
    Polyclonal Antibody for Mouse Estradiol 17-beta-dehydrogenase 12
    Polyclonal Antibody for Mouse Estradiol 17-beta-dehydrogenase 12
    Polyclonal Antibody for Mouse Estradiol 17-beta-dehydrogenase 12
    Polyclonal Antibody for Mouse Estradiol 17-beta-dehydrogenase 12
    Monoclonal Antibody for Mouse Estradiol 17-beta-dehydrogenase 12
    Monoclonal Antibody for Mouse Estradiol 17-beta-dehydrogenase 12
    Monoclonal Antibody for Mouse Estradiol 17-beta-dehydrogenase 12
    Monoclonal Antibody for Mouse Estradiol 17-beta-dehydrogenase 12
    Protein for Mouse Estradiol 17-beta-dehydrogenase 12
    Protein for Mouse Estradiol 17-beta-dehydrogenase 12
    Protein for Mouse Estradiol 17-beta-dehydrogenase 12
    Protein for Mouse Estradiol 17-beta-dehydrogenase 12

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    Precision
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    Linearity
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    References
    1. 1.
      Gambotto A. , Pagliano O. , Robbins P. , Deleo A.
      Submitted (1998-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      strain: BALB/c.
      tissue: Liver.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: BALB/c.
      strain: C57BL/6J.
      strain: NOD.
      tissue: Bone marrow.
      tissue: Cerebellum.
      tissue: Colon.
      tissue: Head.
      tissue: Lung.
      tissue: Thymus.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: FVB/N-3.
      tissue: Mammary tumor.
    4. 4.
      "Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade."
      Moon Y.-A. , Horton J.D.
      J. Biol. Chem.278:7335-7343(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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