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Index > Protein center > HSD17B2(Gene name) > Human
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  • HSD17B2 (Gene name),
  • Estradiol 17-beta-dehydrogenase 2 (Protein name ),  DHB2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    HSD17B2(EDH17B2);
    Protein name:
    Estradiol 17-beta-dehydrogenase 2;
    Alternative:
    20 alpha-hydroxysteroid dehydrogenase(20-alpha-HSD);17-beta-hydroxysteroid dehydrogenase type 2(17-beta-HSD 2);Microsomal 17-beta-hydroxysteroid dehydrogenase;E2DH;1.1.1.239;Testosterone 17-beta-dehydrogenase);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH.
    Subcellular Location:
    Membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    387
    Sequence:
    50:
    MSTFFSDTAW | ICLAVPTVLC | GTVFCKYKKS | SGQLWSWMVC | LAGLCAVCLL | 
    100:
    ILSPFWGLIL | FSVSCFLMYT | YLSGQELLPV | DQKAVLVTGG | DCGLGHALCK | 
    150:
    YLDELGFTVF | AGVLNENGPG | AEELRRTCSP | RLSVLQMDIT | KPVQIKDAYS | 
    200:
    KVAAMLQDRG | LWAVINNAGV | LGFPTDGELL | LMTDYKQCMA | VNFFGTVEVT | 
    250:
    KTFLPLLRKS | KGRLVNVSSM | GGGAPMERLA | SYGSSKAAVT | MFSSVMRLEL | 
    300:
    SKWGIKVASI | QPGGFLTNIA | GTSDKWEKLE | KDILDHLPAE | VQEDYGQDYI | 
    350:
    LAQRNFLLLI | NSLASKDFSP | VLRDIQHAIL | AKSPFAYYTP | GKGAYLWICL | 
    387:
    AHYLPIGIYD | YFAKRHFGQD | KPMPRALRMP | NYKKKAT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    Pfam:
    SMR:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Estradiol 17-beta-dehydrogenase 2
    ELISA Kit for Human Estradiol 17-beta-dehydrogenase 2
    ELISA Kit for Human Estradiol 17-beta-dehydrogenase 2
    CLIA Kit for Human Estradiol 17-beta-dehydrogenase 2
    CLIA Kit for Human Estradiol 17-beta-dehydrogenase 2
    CLIA Kit for Human Estradiol 17-beta-dehydrogenase 2
    Polyclonal Antibody for Human Estradiol 17-beta-dehydrogenase 2
    Polyclonal Antibody for Human Estradiol 17-beta-dehydrogenase 2
    Polyclonal Antibody for Human Estradiol 17-beta-dehydrogenase 2
    Monoclonal Antibody for Human Estradiol 17-beta-dehydrogenase 2
    Monoclonal Antibody for Human Estradiol 17-beta-dehydrogenase 2
    Monoclonal Antibody for Human Estradiol 17-beta-dehydrogenase 2
    Protein for Human Estradiol 17-beta-dehydrogenase 2
    Protein for Human Estradiol 17-beta-dehydrogenase 2
    Protein for Human Estradiol 17-beta-dehydrogenase 2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity."
      Wu L. , Einstein M. , Geissler W.M. , Chan H.K. , Elliston K.O. , Andersson S.
      J. Biol. Chem.268:12964-12969(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];BIOPHYSICOCHEMICAL PROPERTIES
      tissue: Prostate.
    2. 2.
      "The human type II 17 beta-hydroxysteroid dehydrogenase gene encodes two alternatively spliced mRNA species."
      Labrie Y. , Durocher F. , Lachance Y. , Turgeon C. , Simard J. , Labrie C. , Labrie F.
      DNA Cell Biol.14:849-862(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      NIEHS SNPs program
      Submitted (2003-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT THR-121
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Colon.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Bone marrow.
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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