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Index > Protein center > HSD17B7(Gene name) > Human
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  • HSD17B7 (Gene name),
  • 3-keto-steroid reductase (Protein name ),  DHB7_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    HSD17B7(UNQ2563/PRO6243);
    Protein name:
    3-keto-steroid reductase;
    Alternative:
    1.1.1.62;Estradiol 17-beta-dehydrogenase 7);17-beta-hydroxysteroid dehydrogenase 7(17-beta-HSD 7);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Responsible for the reduction of the keto group on the C-3 of sterols.
    Subcellular Location:
    Cell membrane Single-pass membrane protein
    Protein Attributes:
    Sequence length:
    341
    Sequence:
    50:
    MRKVVLITGA | SSGIGLALCK | RLLAEDDELH | LCLACRNMSK | AEAVCAALLA | 
    100:
    SHPTAEVTIV | QVDVSNLQSV | FRASKELKQR | FQRLDCIYLN | AGIMPNPQLN | 
    150:
    IKALFFGLFS | RKVIHMFSTA | EGLLTQGDKI | TADGLQEVFE | TNVFGHFILI | 
    200:
    RELEPLLCHS | DNPSQLIWTS | SRSARKSNFS | LEDFQHSKGK | EPYSSSKYAT | 
    250:
    DLLSVALNRN | FNQQGLYSNV | ACPGTALTNL | TYGILPPFIW | TLLMPAILLL | 
    300:
    RFFANAFTLT | PYNGTEALVW | LFHQKPESLN | PLIKYLSATT | GFGRNYIMTQ | 
    341:
    KMDLDEDTAE | KFYQKLLELE | KHIRVTIQKT | DNQARLSGSC | L
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    SMR:
    UniGene:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human 3-keto-steroid reductase
    ELISA Kit for Human 3-keto-steroid reductase
    ELISA Kit for Human 3-keto-steroid reductase
    CLIA Kit for Human 3-keto-steroid reductase
    CLIA Kit for Human 3-keto-steroid reductase
    CLIA Kit for Human 3-keto-steroid reductase
    Polyclonal Antibody for Human 3-keto-steroid reductase
    Polyclonal Antibody for Human 3-keto-steroid reductase
    Polyclonal Antibody for Human 3-keto-steroid reductase
    Monoclonal Antibody for Human 3-keto-steroid reductase
    Monoclonal Antibody for Human 3-keto-steroid reductase
    Monoclonal Antibody for Human 3-keto-steroid reductase
    Protein for Human 3-keto-steroid reductase
    Protein for Human 3-keto-steroid reductase
    Protein for Human 3-keto-steroid reductase

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Determination of cDNA, gene structure and chromosomal localization of the novel human 17beta-hydroxysteroid dehydrogenase type 7."
      Krazeisen A. , Breitling R. , Imai K. , Fritz S. , Moeller G. , Adamski J.
      FEBS Lett.460:373-379(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1 AND 2)
    2. 2.
      Krazeisen A. , Breitling R. , Imai K. , Fritz S. , Moeller G. , Adamski J.
      Submitted (2000-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    3. 3.
      "Production, purification, and functional analysis of recombinant human and mouse 17beta-hydroxysteroid dehydrogenase type 7."
      Toern S. , Nokelainen P. , Kurkela R. , Pulkka A. , Menjivar M. , Ghosh S. , Coca-Prados M. , Peltoketo H. , Isomaa V. , Vihko P.
      Biochem. Biophys. Res. Commun.305:37-45(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1 AND 3)
      tissue: Placenta.
    4. 4.
      "Cloning of a new human cDNA homologous to Rattus norvegicus ovarian-specific protein."
      Zhou Y. , Yu L. , Zhao S.Y.
      Submitted (1999-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    5. 5.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    6. 6.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    7. 7.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    8. 8.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    10. 10.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Skin.
      tissue: Urinary bladder.
    11. 11.
      "Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis."
      Marijanovic Z. , Laubner D. , Moeller G. , Gege C. , Husen B. , Adamski J. , Breitling R.
      Mol. Endocrinol.17:1715-1725(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION;FUNCTION
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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